Results 81 to 90 of about 120,336 (337)
Advanced Science, EarlyView.Histone lysine crotonylation (Kcr) is a highly conserved posttranslational modification implicated with crucial biological processes. This study reveals that ACSS2‐mediated H4K12cr upregulated CLDN7 transcription to strengthen intestinal epithelial barrier.
Ming Yuan +14 more
wiley +1 more source
Microbial metabolite butyrate promotes induction of IL-10+IgM+ plasma cells.
PLoS ONE, 2022 The microbially-derived short-chain fatty acid butyrate is a central inhibitor of inflammatory innate and adaptive immune responses. Emerging evidence suggests that butyrate induces differentiation of IL-10-producing (IL-10+) regulatory B cells. However,
Bandik Föh +7 more
doaj +1 more source
Therapeutic Potential of Butyrate for Treatment of Type 2 Diabetes
Frontiers in Endocrinology, 2021 Metagenomics studies have shown that type 2 diabetes (T2D) is associated with an altered gut microbiota. Whereas different microbiota patterns have been observed in independent human cohorts, reduction of butyrate-producing bacteria has consistently been
T. Arora, V. Tremaroli
semanticscholar +1 more source
Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells
Redox Biology, 2017 Butyrate is one of the short chain fatty acids, produced by the gut microbiota during anaerobic fermentation of dietary fibres. It has been shown that it can inhibit tumor progression via suppressing histone deacetylase and can induce apoptosis in cancer
Kishor Pant +5 more
doaj
Induction of porcine host defense peptide gene expression by short-chain fatty acids and their analogs. [PDF]
PLoS ONE, 2013 Dietary modulation of the synthesis of endogenous host defense peptides (HDPs) represents a novel antimicrobial approach for disease control and prevention, particularly against antibiotic-resistant infections.
Xiangfang Zeng +7 more
doaj +1 more source
Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis
Advanced Science, EarlyView.Weight cycling in Humans is suspected to dysregulate eating behavior. Mice submitted to body weight cycling by alternating western‐type and regular chow diets display increased hedonic appetite when exposed to a palatable diet, reminiscent of binge‐eating episodes.
Mélanie Fouesnard +13 more
wiley +1 more source
Butyric acid in functional constipation
Gastroenterology Review, 2013 Butyric acid, a short-chain fatty acid, is a major energy source for colonocytes. It occurs in small quantities in some foods, and in the human body, it is produced in the large intestine by intestinalkacteria. This production can be reduced in some cases, for which butyric acid supplementation may be useful.
Jarosław Walkowiak +2 more
openaire +3 more sources
Analysis of microbiota-host communication mediated by butyrate in Atlantic salmon
Computational and Structural Biotechnology Journal, 2023 Butyrate is a microbiota-produced metabolite, sensed by host short-chain fatty acid receptors FFAR2 (Gpr43), FFAR3 (Gpr41), HCAR2 (Gpr109A), and Histone deacetylase (HDAC) that promotes microbiota-host crosstalk.
Rodrigo A. Vargas +15 more
doaj
Frontiers in Cellular and Infection Microbiology, 2022 Introduction and objectiveCholesterol homeostasis is a culmination of cellular synthesis, efflux, and catabolism to important physiological entities where short chain fatty acid, butyrate embodied as a key player.
Oishika Das +14 more
doaj +1 more source
Impact of Diet-Modulated Butyrate Production on Intestinal Barrier Function and Inflammation
Nutrients, 2018 A major challenge in affluent societies is the increase in disorders related to gut and metabolic health. Chronic over nutrition by unhealthy foods high in energy, fat, and sugar, and low in dietary fibre is a key environmental factor responsible for ...
K. B. Bach Knudsen +12 more
semanticscholar +1 more source