Results 61 to 70 of about 104,308 (265)

Butyrate attenuates house dust mite-induced activation of 16HBE bronchial epithelial cells in association with modulation of gene expression

Respiratory Research
Introduction The airway epithelial barrier is the primary defense line of the lungs against allergens, such as house dust mite (HDM). A disrupted airway epithelial barrier plays a major role in asthma development.
Roos E. M. Verstegen, Jennifer Hotie, Margarita Bikineeva, Suze van Brummelen, Johan Garssen, Gert Folkerts, Linette E.M. Willemsen   +6 more
doaj   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Uncovering a novel mechanism: Butyrate induces estrogen receptor alpha activation independent of estrogen stimulation in MCF-7 breast cancer cells

Genetics and Molecular Biology
Butyrate is a promising candidate for an antitumoral drug, as it promotes cancer cell apoptosis and reduces hormone receptor activity, while promoting differentiation and proliferation in normal cells.
Veronica Dayali Gutierrez-Martinez, Alfonso León-Del-Río, Abelardo Camacho-Luis, Victor Manuel Ayala-Garcia, Angélica María Lopez-Rodriguez, Estela Ruiz-Baca, Ivan Meneses-Morales   +6 more
doaj   +1 more source

Mutual Metabolic Interactions in Co-cultures of the Intestinal Anaerostipes rhamnosivorans With an Acetogen, Methanogen, or Pectin-Degrader Affecting Butyrate Production

Frontiers in Microbiology, 2019
The human intestinal tract harbors diverse and complex microbial communities that have a vast metabolic capacity including the breakdown of complex carbohydrates into short chain fatty acids, acetate, propionate, and butyrate.
Thi Phuong Nam Bui, Henk A. Schols, Melliana Jonathan, Alfons J. M. Stams, Willem M. de Vos, Willem M. de Vos, Caroline M. Plugge   +6 more
doaj   +1 more source

Butyration of Lignosulfonate with Butyric Anhydride in the Presence of Choline Chloride

BioResources, 2015
A novel process was developed for the butyration of lignosulfonate (LS) with butyric anhydride in the presence of choline chloride at elevated temperatures. The degree of substitution (DS) was qualitatively and quantitatively determined by Fourier transform infrared spectroscopy using the baseline method.
Lifen Li, Yingcheng Hu, Fangchao Cheng
openaire   +3 more sources

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

Decoupling Chemical and Mechanical Contributions to Capacity Fading in Ni‐Rich Cathodes for Sulfide‐Based All‐Solid‐State Batteries

Advanced Energy Materials, EarlyView.
Ni‐rich cathodes in sulfide‐based ASSBs undergo intertwined (electro)chemical and mechanical degradation. Here, a new diagnostic framework is presented to decouple each contribution by partitioning capacity fading into charge and discharge fading.
Jangwhan Seok, Chanyou Chung, Hyunbeom Lee, Subin Ahn, Seongeun Lee, Sangbin Park, Sunhyun Hwang, Jaeyoung Kim, Jeonghyun Seo, Sungwoo Noh, Juyeong Seong, Sangheon Lee, Won‐Sub Yoon   +12 more
wiley   +1 more source

Exosome‐mediated gut–brain axis signaling in neurodegenerative diseases: Mechanisms, experimental evidence, and therapeutic perspectives—A narrative review

Animal Models and Experimental Medicine, EarlyView.
The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad, Rakesh Ghosh, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Fayez M. Saleh, Amany I. Almars, S. Renuka Jyothi, Rajashree Panigrahi, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

A tailored series of engineered yeasts for the cell-dependent treatment of inflammatory bowel disease by rational butyrate supplementation

Gut Microbes
Intestinal microbiota dysbiosis and metabolic disruption are considered essential characteristics in inflammatory bowel disorders (IBD). Reasonable butyrate supplementation can help patients regulate intestinal flora structure and promote mucosal repair.
Jiahao Wu, He Huang, Lina Wang, Mengxue Gao, Shuxian Meng, Shaolan Zou, Yuanhang Feng, Zeling Feng, Zhixin Zhu, Xiaocang Cao, Bingzhi Li, Guangbo Kang   +11 more
doaj   +1 more source

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

Annals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera, Rossella Di Sapia, Greta Volpedo, Sneha Anand, Eray Sahin, Pasquale Baldassarre, Francesca Buffelli, Andrea Petretto, Chiara Lavarello, James D. Mills, Gabriele Cattaneo, Ilaria Craparotta, Eleonora Aronica, Antonella Riva, Pasquale Striano, Annamaria Vezzani, Teresa Ravizza   +16 more
wiley   +1 more source