Results 81 to 90 of about 133,313 (256)

Beyond Probiotics: Postbiotics for Healthy Aquaculture

Advanced Science, EarlyView.
This critical review assesses limitations of probiotics and proposes postbiotics, preparations of inanimate microorganisms and their metabolites, as a more stable, controlled, and biosafe formulation. Postbiotics offer significant advantages during industrial aquafeed production and storage. However, their practical implementation is currently hindered
Michael Leonidas Chikindas, Delin Xu, Igor V. Popov, Kayque Ordonho Carneiro, Nilufar Arashovna Elova, Gullola Amirovna Bekmurodova, Dildora Amindjanovna Amirsaidova, Astghik Pepoyan, Shakhlo Mirjamalovna Miralimova, Oleg V. Mitrokhin, Liubov S. Sichel, John Tagg, Svetoslav Dimitrov Todorov   +12 more
wiley   +1 more source

A tailored series of engineered yeasts for the cell-dependent treatment of inflammatory bowel disease by rational butyrate supplementation

Gut Microbes
Intestinal microbiota dysbiosis and metabolic disruption are considered essential characteristics in inflammatory bowel disorders (IBD). Reasonable butyrate supplementation can help patients regulate intestinal flora structure and promote mucosal repair.
Jiahao Wu, He Huang, Lina Wang, Mengxue Gao, Shuxian Meng, Shaolan Zou, Yuanhang Feng, Zeling Feng, Zhixin Zhu, Xiaocang Cao, Bingzhi Li, Guangbo Kang   +11 more
doaj   +1 more source

Butyrate production in patients with end-stage renal disease

, 2019
Matty L Terpstra,1–3 Marjan J Sinnige,1,3 Floor Hugenholtz,4 Hessel Peters-Sengers,4 Ester BM Remmerswaal,1,3 Suzanne E Geerlings,2 Frederike J Bemelman11Department of Internal Medicine, Division of Nephrology, Renal Transplant Unit, Amsterdam UMC,
Terpstra ML, Geerlings SE, Peters-Sengers H, Sinnige MJ, Hugenholtz F, Remmerswaal EBM, Bemelman FJ   +6 more
core  

Butyrate, A Major Bacterial-derived Metabolite: Understanding of Butyrate Metabolism in Cancerous Colonocytes [PDF]

, 2017
The prohibitory effects of dietary fiber in colorectal cancer have been identified, although the detailed mechanism of this beneficial effect remain unclear.
Han, Anna
core  

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Sodium butyrate improved intestinal barrier in rabbits

, 2020
The purpose of this study was to investigate the effects of sodium butyrate as a substitute for antibiotics on the production performance and intestinal barrier of meat rabbits.
Lei Liu, Chenyang Li, Xiaoyang Chen, Fuchang Li, Bin Zhang   +4 more
core   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Ammonification Process Is Limited by Transformation of Medium Molecular Weight Nitrogenous Organics but Not Hydrolysis of Proteins

Advanced Science, EarlyView.
A multi‐level analytical framework, integrating protein‐level persistence analysis, nontargeted HRMS formula tracking, peptide‐level proteomics, and targeted monomer quantification under varying redox conditions, together with FMO calculations reveal that ammonification is limited by medium molecular weight nitrogenous multimers.
Jing Li, Junjie Qiu, Fan Lü, Hua Zhang, Pinjing He   +4 more
wiley   +1 more source

Butyrate blocks cell cycle progression in colorectal cancer organoids partially through HDAC2 inhibition

Frontiers in Immunology
IntroductionButyric acid is a major gut microbiota metabolite that exhibits many biological functions, including the suppression of colorectal cancer (CRC) growth.
Banghui Liu, Yujun Huang, Xi Wang, Xiangjun Liu, Yikun Luo, Nan Wang, Hefei Tian, Hefei Tian, Lingxiao Huang, Zhenni Xu, Jinyi Lang, Xudan Lei, Dengqun Liu   +12 more
doaj   +1 more source

Butyrivibrio strains – important butyrate producing bacteria from animal gastro-intestinal tract and current taxonomic status of strains in this genus

Acta Agriculturae Slovenica, 2002
Bacteria belonging to or resembling the genus Butyrivibrio represent a significant proportion of bacterial isolates from different mammalian gastro-intestinal tracts from all over the world.
Tadej ČEPELJNIK, Romana MARINŠEK-LOGAR
doaj   +1 more source