Results 101 to 110 of about 14,314 (224)

Butyrylcholinesterase, variants and metabolic syndrome

, 2018
Butyrylcholinesterase, a hepatic enzyme has a primarily pharmacological role in hydrolyzing esters. Variant forms of the enzymes exist. A hypothesis is presented for their continuing presence over evolution, and suggest a possible modulatory effect on ...
Sridhar, Gumpeny R.; Endocrine and Diabetes Centre, Krishnanagar, Visakhapatnam
core   +1 more source

Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study

Molecules, 2017
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) hydrolyze the neurotransmitter acetylcholine and, thereby, function as coregulators of cholinergic neurotransmission.
Terrone L. Rosenberry, Xavier Brazzolotto, Ian R. Macdonald, Marielle Wandhammer, Marie Trovaslet-Leroy, Sultan Darvesh, Florian Nachon   +6 more
doaj   +1 more source

Synthesis, Analysis, Cholinesterase-Inhibiting Activity and Molecular Modelling Studies of 3-(Dialkylamino)-2-hydroxypropyl 4-[(Alkoxy-carbonyl)amino]benzoates and Their Quaternary Ammonium Salts

Molecules, 2017
Tertiary amines 3-(dialkylamino)-2-hydroxypropyl 4-[(alkoxycarbonyl)amino]benzoates and their quaternary ammonium salts were synthesized. The final step of synthesis of quaternary ammonium salts was carried out by microwave-assisted synthesis.
Tereza Padrtova, Pavlina Marvanova, Klara Odehnalova, Renata Kubinova, Oscar Parravicini, Adriana Garro, Ricardo D. Enriz, Otakar Humpa, Michal Oravec, Petr Mokry   +9 more
doaj   +1 more source

Kinetics and mechanisms of acetylcholinesterase and butyrylcholinesterase inhibition by cardiovascular drugs and, benzodiazepines

, 2014
The goal of this work is to determine enzyme kinetics and mechanisms of acetylcholinesterase and butyrylcholinesterase inhibition by five cardiovascular drugs, lovastatin, simvastatin, amlodipine besylate, nifedipine, and hydralazine hydrochloride, and ...
Chiou, S.Y., Lin, L.Y., Lin, G.L., Lin, G., Tsai, Y.H., Lee, Y.R., Lai, G.W.   +6 more
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Obesity and variants of the GHRL (ghrelin) and BCHE (butyrylcholinesterase) genes

Genetics and Molecular Biology, 2011
Ghrelin coded by the GHRL gene is related to weight-gain, its deactivation possibly depending on its hydrolyzation by butyrylcholinesterase (BChE) encoded by the BCHE gene, an enzyme already associated with the body mass index (BMI).
Vitor G.L. Dantas, Lupe Furtado-Alle, Ricardo L.R. Souza, Eleidi A. Chautard-Freire-Maia   +3 more
doaj   +1 more source

Butyrylcholinesterase as a prognostic marker

, 2018
Tato bakalářská práce se zabývá butyrylcholinesterázou jako jednou z hlavních lidských cholinesteráz. Podrobně popisuje jednotlivé cholinesterázy, jejich odlišnosti a mechanizmy účinku.
Šepsová, Klára
core  

Acetylcholinesterase and Butyrylcholinesterase – Important Enzymes of Human Body

, 2004
The serine hydrolases and proteases are a ubiquitous group of enzymes that is fundamental to many critical lifefunctions. Human tissues have two distinct cholinesterase activities: acetylcholinesterase and butyrylcholinesterase.
Kamil Kuča, Jiří Patočka, Daniel Jun
core   +1 more source

Regulation of attention and response to therapy in dementia by butyrylcholinesterase

, 2003
Objectives: To determine the response of patients with different butyrylcholinesterase genotypes to therapy, and the influence of butyrylcholinesterase on cognition.
Ballard CG, Saxby BK, Grace J, Swan AG, Fairbairn AF, Edwardson JA, McKeith IG, Ford GA, O'Brien KK, Wesnes K, O'Brien JT, Morris CM, Harrington F, Del Ser T   +13 more
core  

Comparison of Active Sites of Butyrylcholinesterase and Acetylcholinesterase Based on Inhibition by Geometric Isomers of Benzene-di-N-Substituted Carbamates

, 2014
We have reported that benzene-1,2-,1,3-, and 1,4-di-N-substituted carbamates (1-15) are characterized as the conformationally constrained inhibitors of acetylcholinesterase and mimic gauche, eclipsed, and anti-conformations of acetylcholine, respectively
Chiou, S.Y., Huang, C.F., Hwang, M.T., Lin, G., 林家立   +4 more
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Changes in Anticholinesterase and Antioxidant Activities of Fruit Products during Storage

Applied Sciences
In this work, compotes, juices, and jams were produced using chokeberry, cherry, apricot, peach, apple (Idared and Champion), wild strawberry, or raspberry fruits.
Dorota Gajowniczek-Ałasa, Ewa Baranowska-Wójcik, Dominik Szwajgier   +2 more
doaj   +1 more source