Results 91 to 100 of about 14,314 (224)
Triterpene-Based Carboxamides Act as Good Inhibitors of Butyrylcholinesterase
A set of overall 40 carboxamides was prepared from five different natural occurring triterpenoids including oleanolic, ursolic, maslinic, betulinic, and platanic acid.
Anne Loesche +4 more
doaj +1 more source
Correlation of butyrylcholinesterase activity within young patients and remaining age strata.
Continuous data are presented as median (interquartile range) and their association with butyrylcholinesterase was assessed using Spearman–Rho correlation coefficient.
Stefan Forster (5663299) +8 more
core +1 more source
Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos +3 more
wiley +1 more source
The Proline-Rich Tetramerization Peptides In Equine Serum Butyrylcholinesterase
Soluble, tetrameric, plasma butyrylcholinesterase from horse has previously been shown to include a non-covalently attached polyproline peptide in its structure. The polyproline peptide matched the polyproline-rich region of human lamellipodin.
Biberoglu, Kevser +3 more
core +1 more source
Late-onset Alzheimer’s disease (AD) is clinically characterized by a progressive decline of memory and other cognitive functions leading to the loss of the ability to perform everyday activities.
Jacek Jasiecki, Bartosz Wasąg
doaj +1 more source
Rivastigmine–Bambuterol Hybrids as Selective Butyrylcholinesterase Inhibitors
Selective butyrylcholinesterase inhibitors are considered promising drug candidates for the treatment of Alzheimer’s disease. In this work, one rivastigmine–bambuterol hybrid (MTR-1) and fourteen of its analogues were synthesized, purified ...
Jie Wu +3 more
core +1 more source
Steady-State Kinetics of Rat Intestinal Butyrylcholinesterase
Objectives: Butyrylcholinesterase is a major detoxification enzyme found in many tissues and body fluids of different organisms. Here, we investigated the steady state kinetics and the effects of heat on soluble butyrylcholinesterase purified from rat ...
BODUR, EBRU +3 more
core
Nowadays extensive volumes of pesticides are employed for agricultural and environmental practices, but they have negative effects on human health. The levels of pesticides are necessarily restricted by international regulatory agencies, thus rapid ...
Fabiana Arduini +5 more
doaj +1 more source
Localization of the peptidase activity of human serum butyrylcholinesterase in a – 50-kDa fragment obtained by limited α-chymotrypsin digestion [PDF]
Purified human serum butyrylcholinesterase (∼90-kDa subunit) is known to exhibit aryl acylamidase and peptidase activity. Limited α-chymotrypsin digestion of the purified butyrylcholinesterase gave three major protein fragments of ∼ 50 kDa, ∼21 kDa and ∼
Rao, Rammohan V. +3 more
core +1 more source
Butyrylcholinesterase K variant and Alzheimer's disease
This study attempted to corroborate findings on the association between butyrylcholinesterase K variant and Alzheimer’s disease. This was performed on an autopsy-confirmed series of patients with Alzheimer’s disease and controls.
Kakulas, B.A. +5 more
core

