Results 91 to 100 of about 24,444 (255)
ChemistryOpen, Volume 15, Issue 4, April 2026.This study optimized solvent‐free geranyl benzoate production using Lipozyme 435, achieving 72% conversion in 6 hours. Open reactors improved yields (>99% in 48 hours) by removing inhibitorymethanol. Methyl benzoate reduced enzyme activity by 54%, though Lipura Flex showed better resistance. Human cell tests confirmed no cytotoxicity.
Domenico Meola +9 more
wiley +1 more source
Chemical Biology &Drug Design, Volume 107, Issue 4, April 2026.Compounds 1j, 1l, 2b, 2j, 3g, and 3l were found to have potent anti‐Alzheimer agents for AChE, BChE inhibitions, neuroprotective effects in the presence of H2O2 and GSK3β inhibitions. ABSTRACT A series of benzimidazoles and its analogs (benzoxazoles and benzothiazoles) bearing a benzohydrazide‐hydrazones moiety at the 2‐position were designed and ...
Gözde Sayar +5 more
wiley +1 more source
Metabolism of profenofos to 4-bromo-2-chlorophenol, a specific and sensitive exposure biomarker. [PDF]
, 2013 Profenofos is a direct acting phosphorothioate organophosphorus (OP) pesticide capable of inhibiting β-esterases such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase.
Chi, Lai-Har +8 more
core +1 more source
Equine Veterinary Education, Volume 38, Issue 4, Page 206-219, April 2026.Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley +1 more source
Triterpene-Based Carboxamides Act as Good Inhibitors of Butyrylcholinesterase
Molecules, 2019 A set of overall 40 carboxamides was prepared from five different natural occurring triterpenoids including oleanolic, ursolic, maslinic, betulinic, and platanic acid.
Anne Loesche +4 more
doaj +1 more source
Effect of stereochemistry on ester hydrolysis by cholinesterases: Implications for radiotracer design [PDF]
, 2001 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91202/1/2580440138_ftp ...
Butch, Elizabeth R. +5 more
core +1 more source
Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase [PDF]
, 2021 Jakub Jończyk +6 more
openalex +1 more source
Assessment of enzyme inhibition : a review with examples from the development of monoamine oxidase and cholinesterase inhibitory drugs [PDF]
, 2017 Both authors are grateful for the collaborations on multi-target drugs facilitated by COST Action CM1103 (2011-2015).The actions of many drugs involve enzyme inhibition.
Ramsay, Rona R., Tipton, Keith F.
core +1 more source
Effects of motor patterns on water-soluble and membrane proteins and cholinesterase activity in subcellular fractions of rat brain tissue [PDF]
Albino rats were kept for a year under conditions of daily motor load or constant hypokinesia. An increase in motor activity results in a rise in the acetylcholinesterase activity determined in the synaptosomal and purified mitochondrial fractions while ...
Cheresharov, L. +2 more
core +1 more source