Results 21 to 30 of about 21,599 (233)

Mutation analysis of SLC26A4 (Pendrin) gene in a Brazilian sample of hearing-impaired subjects

BMC Medical Genetics, 2018
Background Mutations in the SLC26A4 gene are associated with Pendred syndrome and autosomal recessive non-syndromic deafness (DFNB4). Both disorders have similar audiologic characteristics: bilateral hearing loss, often severe or profound, which may be ...
Renata Watanabe Nonose, Karina Lezirovitz, Maria Teresa Balester de Mello Auricchio, Ana Carla Batissoco, Guilherme Lopes Yamamoto, Regina Célia Mingroni-Netto   +5 more
doaj   +1 more source

Biological Synthesis of Low Cytotoxicity Silver Nanoparticles (AgNPs) by the Fungus Chaetomium thermophilum—Sustainable Nanotechnology

Journal of Fungi, 2022
Fungal biotechnology research has rapidly increased as a result of the growing awareness of sustainable development and the pressing need to explore eco-friendly options.
Mariana Fuinhas Alves, Ariane Caroline Campos Paschoal, Tabata D’Maiella Freitas Klimeck, Crisciele Kuligovski, Bruna Hilzendeger Marcon, Alessandra Melo de Aguiar, Patrick G. Murray   +6 more
doaj   +1 more source

Hematopoietic stem cell transplantation in childhood: current status and perspectives [PDF]

, 2009
Hematopoietic stem cell transplantation is a treatment option for a large number of children with malignant and non-malignant diseases. The objective of this article is to present the current status of hematopoietic stem cell transplantation in the ...
Seber, Adriana
core   +1 more source

The Inflammatory Status of Soluble Microenvironment Influences the Capacity of Melanoma Cells to Control T-Cell Responses

Frontiers in Oncology, 2022
The development of immunotherapeutic approaches for the treatment of melanoma requires a better understanding of immunoescape mechanisms of tumor cells and how they interact with other tumor-resident cell types.
Gabriela Muller Reche Bogéa, Gabriela Muller Reche Bogéa, Amandda Évelin Silva-Carvalho, Amandda Évelin Silva-Carvalho, Luma Dayane de Carvalho Filiú-Braga, Luma Dayane de Carvalho Filiú-Braga, Francisco de Assis Rocha Neves, Felipe Saldanha-Araujo   +7 more
doaj   +1 more source

Skin Wound Healing Model - Excisional Wounding and Assessment of Lesion Area

Bio-Protocol, 2015
This protocol focus on the most common surgical mouse model of cutaneous excisional wound healing used to study the cellular and molecular pathways involved in wound repair and regeneration as well as in translational applications such as the evaluation ...
Camila Moreira, Puebla Cassini-Vieira, Mariana da Silva, Lucíola Barcelos   +3 more
doaj   +1 more source

3D Poly(Lactic Acid) Scaffolds Promote Different Behaviors on Endothelial Progenitors and Adipose-Derived Stromal Cells in Comparison With Standard 2D Cultures

Frontiers in Bioengineering and Biotechnology, 2021
Tissue engineering is a branch of regenerative medicine, which comprises the combination of biomaterials, cells and other bioactive molecules to regenerate tissues.
Giuliana Biagini, Alexandra Cristina Senegaglia, Tarciso Pereira, Lucas Freitas Berti, Bruna Hilzendeger Marcon, Marco Augusto Stimamiglio   +5 more
doaj   +1 more source

DONOR SCREENING AS AN ESSENTIAL FACTOR IN THE EFFICIENCY OF DOUBLE PLATELET COLLECTION BY APHERESIS

Hematology, Transfusion and Cell Therapy
Background/case studies: The need for platelets collected by apheresis in Brazil has been gradually increasing. Blood banks that seek quality and transfusion safety choose to use it whenever available.
CRA Silva, A Crispim, G Dourado, F Pimenta, B Menezes, A Silva, F Teixeira, E Bariani, C Bariani   +8 more
doaj   +1 more source

Infection with multidrug‐resistant gram‐negative bacteria in a pediatric oncology intensive care unit: risk factors and outcomes

Jornal de Pediatria (Versão em Português), 2015
Objective: This study aimed at evaluating the predictors and outcomes associated with multidrug‐resistant gram‐negative bacterial (MDR‐GNB) infections in an oncology pediatric intensive care unit (PICU).
Patrícia de Oliveira Costa, Elias Hallack Atta, André Ricardo Araújo da Silva   +2 more
doaj   +1 more source

Using inhibition of the adipogenesis of adipose-derived stem cells in vitro for toxicity prediction

MethodsX, 2021
In vitro stem cell models are used as alternatives to animal models and are important tools for cytotoxicity studies. Researchers can determine the effects of test substances on human cells by evaluating cell viability and differentiation.
Ana Paula Ressetti Abud, Ariane Caroline Campos Paschoal, Crisciele Kuligovski, Rodrigo Rêgo Barros Caruso, Bruno Dallagiovanna, Alessandra Melo de Aguiar   +5 more
doaj   +1 more source

Estimation of Wound Tissue Neutrophil and Macrophage Accumulation by Measuring Myeloperoxidase (MPO) and N-Acetyl-β-D-glucosaminidase (NAG) Activities

Bio-Protocol, 2015
The inflammatory response is essential to the reestablishment of cutaneous homeostasis following injury. In this context, leukocytes arrive at the wound site and orchestrate essential events in the wound healing process.
Puebla Cassini-Vieira, Camila Moreira, Mariana da Silva, Lucíola Barcelos   +3 more
doaj   +1 more source