Results 51 to 60 of about 1,911 (134)

Fast dehydration reduces bundle sheath conductance in C4 maize and sorghum

open access: yesNew Phytologist, Volume 244, Issue 6, Page 2197-2209, December 2024.
Summary In the face of anthropogenic warming, drought poses an escalating threat to food production. C4 plants offer promise in addressing this threat. C4 leaves operate a biochemical CO2 concentrating mechanism that exchanges metabolites between two partially isolated compartments (mesophyll and bundle sheath), which confers high‐productivity ...
Chandra Bellasio   +3 more
wiley   +1 more source

H218O vapour labelling reveals evidence of radial Péclet effects, but in not all leaves

open access: yesNew Phytologist, Volume 244, Issue 4, Page 1263-1274, November 2024.
Summary Contradictory evidence exists regarding the relevance of Péclet‐like gradients in leaf water isotopes, making it difficult to accurately predict variation in isotope composition. Here, we use H218O vapour labelling to directly test whether leaf water isotopes diffuse back into the xylem to be carried forward to more distal leaf portions ...
Margaret M. Barbour   +2 more
wiley   +1 more source

Understanding rare variant contributions to autism: lessons from dystrophin-deficient model

open access: yesnpj Genomic Medicine
Duchenne and Becker Muscular Dystrophy are dystrophinopathies with a prevalence of 1:5000–6000 males, caused by pathogenic variants in DMD. These conditions are often accompanied by neurodevelopmental disorders (NDDs) like autism (ASD; ~20%) and ...
Claudia Ismania Samogy Costa   +15 more
doaj   +1 more source

Plasmodesmata and intercellular molecular traffic control

open access: yesNew Phytologist, Volume 243, Issue 1, Page 32-47, July 2024.
Summary Plasmodesmata are plasma membrane‐lined connections that join plant cells to their neighbours, establishing an intercellular cytoplasmic continuum through which molecules can travel between cells, tissues, and organs. As plasmodesmata connect almost all cells in plants, their molecular traffic carries information and resources across a range of
Estee E. Tee, Christine Faulkner
wiley   +1 more source

Molecular and functional anticancer effects of GLP/G9a inhibition by UNC0646 in MeWo melanoma cells

open access: yesHeliyon
In recent years, histone methyltransferases (HMTs) have emerged as important therapeutic targets in cancer due to their oncogenic role. Herein, we used the GLP/G9a inhibitor UNC0646 to assess whether the inhibition of such HMTs could induce cell death in
Luma Dayane de Carvalho Filiú-Braga   +4 more
doaj   +1 more source

Rare CACNA1H and RELN variants interact through mTORC1 pathway in oligogenic autism spectrum disorder

open access: yesTranslational Psychiatry, 2022
Oligogenic inheritance of autism spectrum disorder (ASD) has been supported by several studies. However, little is known about how the risk variants interact and converge on causative neurobiological pathways.
André Luíz Teles e Silva   +12 more
doaj   +1 more source

A pilot study of antimicrobial effects and ototoxicity of a Norway spruce (Picea abies) resin‐based canine otic rinse product

open access: yesVeterinary Dermatology, Volume 35, Issue 3, Page 325-336, June 2024.
Background – Norway spruce (Picea abies) resin‐based products are used in human medicine. A resin‐based otic rinse also could be useful in supportive care of canine otitis externa (COE), yet information on its antimicrobial effect against canine pathogens or ototoxicity is lacking.
Elina Aimo‐Koivisto   +5 more
wiley   +1 more source

Differential methylation is associated with non-syndromic cleft lip and palate and contributes to penetrance effects

open access: yesScientific Reports, 2017
Non-syndromic cleft lip and/or palate (NSCLP) is a common congenital malformation with a multifactorial model of inheritance. Although several at-risk alleles have been identified, they do not completely explain the high heritability.
Lucas Alvizi   +6 more
doaj   +1 more source

Functional traits of fossil plants

open access: yesNew Phytologist, Volume 242, Issue 2, Page 392-423, April 2024.
Summary A minuscule fraction of the Earth's paleobiological diversity is preserved in the geological record as fossils. What plant remnants have withstood taphonomic filtering, fragmentation, and alteration in their journey to become part of the fossil record provide unique information on how plants functioned in paleo‐ecosystems through their traits ...
Jennifer C. McElwain   +14 more
wiley   +1 more source

IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS‐associated amyotrophic lateral sclerosis

open access: yesBrain Pathology, Volume 34, Issue 1, January 2024.
FUS R521H motor neurons derived from IPSCs exhibit reduced viability, decreased protein synthesis, and diminished cytokine production when exposed to oxidative stress. Treatment with IFNy improves translation rates and mitigates apoptosis caused by oxidative injury.
Amanda Faria Assoni   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy