Results 81 to 90 of about 18,358 (184)

Hematopoietic stem cells transplantation and acute myeloid leukemia: Brazilian guidelines [PDF]

, 2010
The objective of this work was to define guidelines for the indication of hematopoietic stem cells transplantation (HSCT) in the treatment of acute myeloid leukemia (AML) in Brazil.
Arantes, Adriano de Moraes [UNIFESP], Dulley, Frederico, Hamerschlak, Nelson, Kerbauy, Fábio Rodrigues [UNIFESP], Paton, Eduardo, Saboya, Rosaura, Silla, Lucia Mariano R.   +6 more
core   +2 more sources

Differential methylation in blood pressure control genes is associated to essential hypertension in African Brazilian populations

Epigenetics
While genetic studies have provided insights into essential hypertension (EH, defined by high blood pressure ≥140/90 mmHg), investigation through epigenetics may address gaps in understanding its heritability.
Camila Cristina Avila Martins, Mariana Maschietto, Lilian Kimura, Lucas Alvizi, Kelly Nunes, Vinícius Magalhães Borges, Ana Cristina Victorino Krepischi, Regina Célia Mingroni-Netto   +7 more
doaj   +1 more source

Inhibition of Lysyl Oxidases Impairs Migration and Angiogenic Properties of Tumor-Associated Pericytes

Stem Cells International, 2017
Pericytes are important cellular components of the tumor microenviroment with established roles in angiogenesis and metastasis. These two cancer hallmarks are modulated by enzymes of the LOX family, but thus far, information about LOX relevance in tumor ...
Aline Lopes Ribeiro, Carolini Kaid, Patrícia B. G. Silva, Beatriz A. Cortez, Oswaldo Keith Okamoto   +4 more
doaj   +1 more source

Characterization of ibrutinib's effects on the morphology, proliferation, phenotype, viability, and anti-inflammatory potential of adipose-derived mesenchymal stromal cells

Scientific Reports
Ibrutinib (IB) is a tyrosine kinase inhibitor (TKI) that has immunomodulatory action and can be used as second-line therapy for steroid-refractory or steroid-resistant chronic Graft versus Host Disease (cGVHD).
Amandda Évelin Silva-Carvalho, Elizabete Cristina Iseke Bispo, Ingrid Gracielle Martins da Silva, José Raimundo Correa, Juliana Lott Carvalho, Guilherme Martins Gelfuso, Felipe Saldanha-Araujo   +6 more
doaj   +1 more source

Altered Oxygen Metabolism Associated to Neurogenesis of Induced Pluripotent Stem Cells Derived from a Schizophrenic Patient

Cell Transplantation, 2012
Schizophrenia has been defined as a neurodevelopmental disease that causes changes in the process of thoughts, perceptions, and emotions, usually leading to a mental deterioration and affective blunting.
Bruna Da Silveira Paulsen, Renata De Moraes Maciel, Antonio Galina, Mariana Souza Da Silveira, Cleide Dos Santos Souza, Hannah Drummond, Ernesto Nascimento Pozzatto, Hamilton Silva Junior, Leonardo Chicaybam, Raffael Massuda, Pedro Setti-Perdigão, Martin Bonamino, Paulo Silva Belmonte-De-Abreu, Newton Gonçalves Castro, Helena Brentani, Stevens Kastrup Rehen   +15 more
doaj   +1 more source

Genetic heterogeneity in autosomal recessive hearing loss: a survey of Brazilian families

Frontiers in Genetics
IntroductionHearing loss is a frequent sensory impairment type in humans, with about 50% of prelingual cases being attributed to genetic factors. Autosomal recessive hearing loss (ARHL) exhibits great locus heterogeneity and is responsible for 70%–80% of
Larissa Nascimento Antunes, Alex Marcel Moreira Dias, Beatriz Cetalle Schiavo, Beatriz C. A. Mendes, Debora Romeo Bertola, Debora Romeo Bertola, Karina Lezirovitz, Regina Célia Mingroni-Netto   +7 more
doaj   +1 more source

Importância das Células Tronco Mesenquimais no desenvolvimento do câncer de mama [PDF]

, 2011
La mayoría de las pacientes con cáncer de mama (PCM) avanzado desarrollan metástasis óseas, de tipo osteolíticas, como resultado de un desbalance entre los procesos de os-teogénesis, osteoclastogénesis y resorción ósea.
Chasseing, Norma Alejandra, Fernández Vallone, Valeria Beatriz, Labovsky, Vivian, Martinez, Leandro Marcelo   +3 more
core   +1 more source

iNOS Activity Modulates Inflammation, Angiogenesis, and Tissue Fibrosis in Polyether-Polyurethane Synthetic Implants

Mediators of Inflammation, 2015
There is considerable interest in implantation techniques and scaffolds for tissue engineering and, for safety and biocompatibility reasons, inflammation, angiogenesis, and fibrosis need to be determined.
Puebla Cassini-Vieira, Fernanda Assis Araújo, Filipi Leles da Costa Dias, Remo Castro Russo, Silvia Passos Andrade, Mauro Martins Teixeira, Luciola Silva Barcelos   +6 more
doaj   +1 more source

Combined Effects of Pericytes in the Tumor Microenvironment

Stem Cells International, 2015
Pericytes are multipotent perivascular cells whose involvement in vasculature development is well established. Evidences in the literature also suggest that pericytes display immune properties and that these cells may serve as an in vivo reservoir of ...
Aline Lopes Ribeiro, Oswaldo Keith Okamoto   +1 more
doaj   +1 more source

Isolation, expansion, and characterization of equine adipose-derived stem cells [PDF]

, 2012
Devido aos excelentes resultados obtidos em pesquisas com células-tronco e suas aplicabilidades promissoras, a terapia com estas células encontra-se em momento de máxima ascensão, estimulando assim, inúmeras pesquisas.
Bravo, Martha de Oliveira, Dumont, Cinthia Beatriz da Silva, Filgueiras, Richard Rocha, Godoy, Roberta Ferro de, Hashimoto, Hetielle Harumi, Moraes, Júlia Miranda de   +5 more
core