Results 1 to 10 of about 36,580 (117)
Medicina, 2023 Different cancers have multiple genetic mutations, which vary depending on the affected tumour tissue. Small biopsies may not always represent all the genetic landscape of the tumour.
Veronica Aran +7 more
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The genotypic and phenotypic impact of hypoxia microenvironment on glioblastoma cell lines
BMC Cancer, 2021 Background Glioblastoma is a fatal brain tumour with a poor patient survival outcome. Hypoxia has been shown to reprogram cells towards a stem cell phenotype associated with self-renewal and drug resistance properties.
Lucy Wanjiku Macharia +9 more
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Recent advances in the use of liquid biopsy to fight central nervous system tumors
Cancer Treatment and Research Communications, 2023 Brain tumors are considered one of the deadliest types of cancer, being challenging to treat, especially due to the blood-brain barrier, which has been linked to treatment resistance.
Carlos Pilotto Heming +3 more
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Case Report: Anomalous Experience in a Dissociative Identity and Borderline Personality Disorder
Frontiers in Psychiatry, 2022 IntroductionDissociative identity disorder, formerly called multiple personality disorder, is a rupture of identity characterized by the presence of two or more distinct personality states, described in some cultures as an experience of possession ...
Hugo André de Lima Martins +4 more
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P-glycoprotein and cancer: what do we currently know?
Heliyon, 2022 Acquired resistance during cancer treatment is unfortunately a frequent event. There are several reasons for this, including the ability of the ATP-binding cassette transporters (ABC transporters), which are integral membrane proteins, to export ...
Carlos Pilotto Heming +5 more
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Psychosocial approach of epilepctic patients
Arquivos de Neuro-Psiquiatria, 1992 Psychosocial aspects of patient's life were analysed in 30 patients with epilepsy aged over 18 years old. At this age people usually are apt by themselves to exert several psychosocial activities.
N. O. Facure, C.m.b. Toniolo, M. Maeda
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Gliomas and the vascular fragility of the blood brain barrier
Frontiers in Cellular Neuroscience, 2014 Astrocytes, members of the glial family, interact through the exchange of soluble factors or by directly contacting neurons and other brain cells, such as microglia and endothelial cells. Astrocytic projections interact with vessels and act as additional
Luiz Gustavo eDubois +15 more
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Doença de Alzheimer: relação entre o tempo de doença e seu estadiamento
Arquivos de Neuro-Psiquiatria, 1993 São analisados 49 pacientes com diagnóstico clínico de doença de Alzheimer, submetidos a avaliação neuropsicológica para estadiamento dia doença segundo a escala de Reisberg.
Nubor O. Facure +2 more
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Annals of Intensive Care, 2019 Background Aneurysmal subarachnoid hemorrhage (SAH) is an acute cerebrovascular disease associated with high mortality and long-term functional impairment among survivors.
Bruno Gonçalves +6 more
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A highlight on Sonic hedgehog pathway
Cell Communication and Signaling, 2018 Hedgehog (Hh) signaling pathway plays an essential role during vertebrate embryonic development and tumorigenesis. It is already known that Sonic hedgehog (Shh) pathway is important for the evolution of radio and chemo-resistance of several types of ...
Gabriela Basile Carballo +3 more
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