Results 91 to 100 of about 3,837,372 (238)

Variable coordination of amine functionalised N-heterocyclic carbene ligands to Ru, Rh and Rr: C-H and N-H activation and catalytic transfer hydrogenation [PDF]

, 2011
Chelating amine and amido complexes of late transition metals are highly valuable bifunctional catalysts in organic synthesis, but complexes of bidentate amine–NHC and amido–NHC ligands are scarce.
Arita, Blake, Boutadla, Boutadla, Brewster, Cariou, Christopher G. Daly, Corberan, Corberan, Corberan, Corberan, Cross, Davies, Grützmacher, Gürbü, Haack, Hanasaka, Hanasaka, Hanasaka, Ikariya, Ikariya, Ikariya, Ito, Ito, Ito, Ito, Ito, Jong, Kuldip Singh, Kuwata, Lalrempuia, Li, Murata, Noyori, O, O, O, Poyatos, Prades, Prades, Sandoval, Shannon, Spek, Tanabe, Viciano, Warren B. Cross, White, Youcef Boutadla, Zanardi, Özdemir   +49 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Selective Borylation of C(sp3)−H Bond of Methyl Ethers Catalyzed by Iron Complexes Bearing Anionic Benzene‐Based PCP‐Pincer Ligands

ChemistryEurope
Highly selective catalytic C(sp3)−H borylation of methoxy groups has been achieved using newly synthesized iron complexes bearing benzene‐based PCP‐type pincer ligands as catalysts. Reactions of various aryl and alkyl methyl ethers as substrates with bis(
Shogo Kuriyama, Yuto Suga, Ken Sakata, Yoshiaki Nishibayashi   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Vanadium(V) tetra-phenolate complexes: synthesis, structural studies and ethylene homo-(co-)polymerization capability [PDF]

, 2015
Reaction of α,α,α′,α′-tetrakis(3,5-di-tert-butyl-2-hydroxyphenyl)-p-xylene (p-L¹H₄) with two equivalents of [VO(OR)₃] (R = nPr, tBu) in refluxing toluene afforded, after work-up, the complexes {[VO(OnPr)(THF)]₂ (μ-p-L¹)}·2(THF) (1·2(THF)) or {[VO(OtBu)]₂
Elsegood, Mark R. J., Michiue, K., Michiue, Kenji, Prior, Timothy J., Redshaw, Carl, Walton, Mark J.   +5 more
core   +2 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

A Generalized Approach for Distal C–H Arylation of Organic Building Blocks: Unveiling the Role of Counter Anion

Advanced Science
Aryl–aryl coupling at remote C–H sites remain a formidable challenge in organic synthesis, particularly for electronically biased arenes and heteroarenes.
Jagrit Grover, Gaurav Prakash, Astam Mandal, Devika Ghosh, Siddhartha Maiti, Claire Empel, Debabrata Maiti   +6 more
doaj   +1 more source

Small-polaron hopping conductivity in bilayer manganite La$_{1.2}$Sr$_{1.8}$Mn$_{2}$O$_{7}$

, 2003
We report anisotropic resistivity measurements on a La$_{1.2}$Sr$_{1.8}$Mn$_{2}$O$_{7}$ single crystal over a temperature $T$ range from 2 to 400 K and in magnetic fields $H$ up to 14 T.
C. C. Almasan, C. L. Zhang, C.D. Potter, C.L. Zhang, C.N. Jiang, D. Emin, D.B. Romero, D.C. Worledge, G. Jakob, G.F. Dionne, H.J. Lee, J. L. Sarrao, J. S. Gardner, J.-S. Zhou, J.F. Mitchell, J.M. De Teresa, J.M. De Teresa, J.Z. Sun, K. Hirota, K. Kubo, L. Vasiliu-Doloc, M. Oretzki, M. Viret, N.O. Moreno, P. Wagner, R. Raffaelle, S. Nakamae, T. Ishikawa, T. Kimura, T.G. Perring, X. J. Chen, Y. Moritomo   +31 more
core   +1 more source

C-Jun N-terminal kinase 2 promotes liver injury via the mitochondrial permeability transition after hemorrhage and resuscitation [PDF]

, 2012
Hemorrhagic shock leads to hepatic hypoperfusion and activation of mitogen-activated stress kinases (MAPK) like c-Jun N-terminal kinase (JNK) 1 and 2. Our aim was to determine whether mitochondrial dysfunction leading to hepatic necrosis and apoptosis ...
Czerny, Christoph, Lehnert, Mark, Lemasters, John J., Maldonado, Eduardo N., Marzi, Ingo, Theruvath, Tom Prakash, Zhong, Zhi   +6 more
core   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source