Results 101 to 110 of about 7,841,789 (286)
An atom-efficient and convergent approach to the preparation of NS5A inhibitors by C-H activation [PDF]
, 2016 A novel approach of the convergent functionalisation of aryl dibromides to form NS5A type inhibitors using C–H activation is reported. The focus of investigation was to reduce the formation of homodimeric side product, as well as to investigate the scope
Moore, Thomas O. +2 more
core +1 more source
Enantioselective remote C–H activation directed by a chiral cation
Science, 2020 Asymmetry on the plus side Numerous positively charged metal catalysts have been paired with chiral negative ions to select for just one of two mirror-image products. Genov et al.
Georgi R. Genov +4 more
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Probing the C-H Activation of Linear and Cyclic Ethers at (PNP)Ir [PDF]
, 2009 Interaction of the amido/bis(phosphine)-supported (PNP)Ir fragment with a series of linear and cyclic ethers is shown to afford, depending on substrate, products of α,α-dehydrogenation (carbenes), α,β-dehydrogenation (vinyl ethers), or decarbonylation ...
Chen, Chun-Hsing +6 more
core +1 more source
Chiral Catalysts for Pd0-Catalyzed Enantioselective C-H Activation.
Chemistry, 2020 In the past decades, processes that involve transition-metal catalysis have represented a major part of synthetic tools. Recently, the interest shifted from the well-established cross-coupling reactions to C-H bond functionalization, thus making it a ...
Oleksandr Vyhivskyi +3 more
semanticscholar +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
ChemistryEuropeHighly selective catalytic C(sp3)−H borylation of methoxy groups has been achieved using newly synthesized iron complexes bearing benzene‐based PCP‐type pincer ligands as catalysts. Reactions of various aryl and alkyl methyl ethers as substrates with bis(
Shogo Kuriyama +3 more
doaj +1 more source
Iron-Catalyzed C–H Functionalizations under Triazole-Assistance
Molecules, 2020 3d transition metals-catalyzed C–H bond functionalizations represent nowadays an important tool in organic synthesis, appearing as the most promising alternative to cross-coupling reactions.
Matteo Lanzi, Gianpiero Cera
doaj +1 more source
Angewandte Chemie, 2019 Ruthenium-catalyzed meta-C-H activation of arenes at room temperature is reported to proceed under blue-light irradiation. A variety of heteroarenes are compatible with this photochemical process, which leads to the corresponding meta C-C coupling ...
Arunachalam Sagadevan, M. Greaney
semanticscholar +1 more source
Chemistry, 2020 Polycycles are abundantly present in numerous advanced chemicals, functional materials, bioactive molecules and natural products. However, the strategies for the synthesis of polycycles are limited to classical reactions and transition metal-catalyzed ...
Liangliang Song, E. V. Van der Eycken
semanticscholar +1 more source