Synthesis, In Silico and In Vivo Toxicity Assessment of Functionalized Pyridophenanthridinones via Sequential MW-Assisted Intramolecular Friedel-Crafts Alkylation and Direct C-H Arylation. [PDF]
Ortiz Villamizar MC +4 more
europepmc +1 more source
Development of a New Dehydrogenative Method for the Synthesis of Polydioxythiophenes
Oxygen is used as the sole oxidant to synthesize several thiophene‐based polymers by Oxidative Direct Arylation Polymerization. Among these polymers, sulfonated PEDOT is synthesized with Mn values of 18 kDa. Conductivity values of up to 14 S/cm are measured, and show that these polymers exhibit their highest conductivity without oxidative treatment ...
Samuel Brassard +2 more
wiley +1 more source
Synthesis, Characterization, and Application of Pd(II)-NNN Pincer Complexes in Direct C-H Arylation of Heteroarenes with Aryl Bromides. [PDF]
Swami PN +5 more
europepmc +1 more source
Design and Synthesis of a Potent, Cell Active Purine‐Based Amidoxime Against the Dengue Virus
Scaffold hopping from our previous indolazepinone hit exemplifies purine SP‐835G with DENV2 EC50 0.1 µM, CC50>100 µM, clogP 3.61. Docking studies support its amidine metabolite operates as an allosteric inhibitor of DENV(pro). A flexible ether linker appears pivotal for enhancing binding and activity.
Dimitrios Kiousis +8 more
wiley +1 more source
Versatile Palladium-Catalyzed C-H Arylation of Fluoroarenes with 2-Chloropyridine Derivatives. [PDF]
Belnome F +6 more
europepmc +1 more source
Palladium-Catalyzed Ortho C-H Arylation of Unprotected Anilines: Chemo- and Regioselectivity Enabled by the Cooperating Ligand [2,2'-Bipyridin]-6(1H)-one. [PDF]
Pinilla C +3 more
europepmc +1 more source
Enantioselective β-C-H Arylation of α-Fluoroalkyl Cyclopropane and Cyclobutane Carboxylic Acids. [PDF]
Phan DQ, Yu JQ.
europepmc +1 more source
Ligand-promoted palladium-catalyzed β-methylene C-H arylation of primary aldehydes. [PDF]
Yang K +10 more
europepmc +1 more source
Palladium/norbornene-catalyzed distal alkenyl C-H arylation and alkylation of cis-olefins. [PDF]
Wu Z, Fatuzzo N, Dong G.
europepmc +1 more source
An unprecedented example of sequential pyridinyl directed C-C cleavage of secondary alcohols/oxidative arylation with arylsilanes via Rh(III) catalysis is reported.
Lei, Zhi-Quan +6 more
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