Results 151 to 160 of about 28,217,704 (208)

Regenerable Heterogeneous Palladium Single-Atom Catalysts for Direct C-H Arylation. [PDF]

J Am Chem Soc
Olikauskas V, Usteri ME, Bugaev A, Plodinec M, Mitchell S, Waser J, Pérez-Ramírez J.   +6 more
europepmc   +1 more source

S,O-Ligand Promoted meta-C-H Arylation of Anisole Derivatives via Palladium/Norbornene Catalysis. [PDF]

Angew Chem Int Ed Engl, 2022
Sukowski V, van Borselen M, Mathew S, Fernández-Ibáñez MÁ.   +3 more
europepmc   +1 more source

Hydride Relay Exchange Mechanism for the Heterocyclic C–H Arylation of Benzofuran and Benzothiophene Catalyzed by Pd Complexes

The mechanism and regioselectivity of the heterocyclic C–H arylation of benzofuran and benzothiophene catalyzed by Pd­(OAc)2 complexes were investigated using the density functional theory (DFT) method. The Pd(0)­L2(PhI) complex (L = HOAc) is proposed to
Zhewei Li (8928272), Luocong Wang (13870639), Yangqiu Liu (8928269), Min Pu (443095), Fuxing Shi (9095410), Ming Lei (161082), Peihuan Zhang (13870636)   +6 more
core   +1 more source

Scaffold Hopping Provides Liver X Receptor Agonist With Preference for the β Subtype

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
A scaffold hopping strategy was pursued to enhance the binding pocket engagement and β‐subtype selectivity of liver X receptor agonist 2. The resulting spirocyclic lead compound, (S)‐7, demonstrates superior potency, enhanced potency‐based selectivity for LXRβ, and improved microsomal stability over the existing scaffold.
Annette Kärcher, Fiona L. Motel, Felix F. Lillich, Astrid Kaiser, Ewgenij Proschak, Pascal Heitel   +5 more
wiley   +1 more source

Deprotonation and Alkylation of Weakly Acidic C(sp3)─H Bonds Through In Situ Generation of a Strong Hydride Base From 1,1,3,3‐Tetramethyldisiloxane and Potassium tert‐Butoxide

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
The use of 1,1,3,3‐tetramethyldisiloxane (TMDSO) and potassium tert‐butoxide enables direct alkylation of weakly acidic carbon–hydrogen bonds with alkyl halides. Experimental and computational studies support the formation of a substrate‐associated hydride‐like base, providing a single‐step alternative to the classical deprotonation and electrophile ...
Piers St. Onge, Brandon White, Han Yao, Travis Dudding, Stephen G. Newman   +4 more
wiley   +2 more sources

Enabling Base-Free Direct C-H Arylation of Thiophene Derivatives: Glycerol-Derived Solvents as Active Reaction Media. [PDF]

ChemSusChem
Gracia-Barberán S, Nejrotti S, Leal-Duaso A, Centrella B, Sanson A, Mayoral JA, Barolo C, Pires E, Bonomo M.   +8 more
europepmc   +1 more source

Catalytic Photoredox C-H Arylation of 4-Oxo-4<i>H</i>-pyrido[1,2-<i>a</i>]pyrimidine-3-diazonium Tetrafluoroborates and Related Heteroaryl Diazonium Salts. [PDF]

J Org Chem, 2023
Antolinc K, Brodnik H, Grošelj U, Štefane B, Petek N, Svete J.   +5 more
europepmc   +1 more source

Photosensitizing Au(I) Catalysis With Coumarins

Chemistry – A European Journal, Volume 32, Issue 38, 13 October 2026.
A Au(I) complex with a tethered coumarin fragment was synthesized and characterized by UV‐vis and emission spectroscopy. Its ability to facilitate photo‐driven cross‐coupling reactions through single‐electron and energy transfer events was evaluated. ABSTRACT Gold catalysis shows versatility in a wide range of challenging transformations, wherein light‐
Liliana Capulín Flores, Jacob J. van der Wal, Johannes E. M. N. Klein   +2 more
wiley   +1 more source

Synthesis of S‐Arylthioxanthonium Trifluoromethanesulfonates From Thioxanthones and Diaryliodonium Salts by Copper(II) Catalysis and Application to Aryl–Heteroaryl Bond Formation by Direct LED Irradiation

European Journal of Organic Chemistry, Volume 29, Issue 38, 13 October 2026.
A straightforward Cu(II)‐catalyzed synthesis of S‐arylthioxanthonium trifluoromethanesulfonates from readily available thioxanthones and diaryliodonium salts is described. A broad range of salts is obtained in moderate to good yields. It is further demonstrated that S‐arylthioxanthonium trifluoromethanesulfonates act as aryl radical precursors under ...
Pierre Boulay, Fabrice Morlet‐Savary, Jean‐Michel Becht   +2 more
wiley   +1 more source

Carbazole and Diketopyrrolopyrrole-Based D-A π-Conjugated Oligomers Accessed via Direct C-H Arylation for Opto-Electronic Property and Performance Study. [PDF]

Molecules, 2022
Zhang X, Feng L, Zhang K, Liu SY.
europepmc   +1 more source