Results 61 to 70 of about 19,520 (191)

Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives

Chemistry – A European Journal, EarlyView.
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome, Péter P. Fehér, András Stirling, Csongor G. Németh, Tamás Hergert, György M. Keserű, Péter Ábrányi‐Balogh   +6 more
wiley   +1 more source

Gold-Catalyzed Direct Arylation [PDF]

, 2012
Gently Coupled Linked aryl rings are found in a broad range of commercial chemical products. Currently, the most versatile synthetic route to this motif involves cross-coupling of one ring with a halide substituent to another ring ...
Ball, L. T., Lloyd-jones, G. C., Russell, C. A.   +2 more
core   +1 more source

Pd‐Catalyzed C─C Bond Borylation of Biphenylenes Leading to Tri‐Ortho‐Substituted Biaryls

Chemistry – A European Journal, EarlyView.
Palladium‐catalyzed ring‐opening C─C borylation of 1‐substituted biphenylenes yields a range of o,o,o′‐trisubstituted biaryls with two ortho‐boryl groups via selective cleavage of the least hindered C─C bond. The resulting diborylated products are readily amenable to sequential, site‐selective postfunctionalization.
Robyn V. Presland, Konstantin V. Luzyanin, Luke A. Wilkinson, Oliver L. Jacobs, Nathan R. Halcovitch, Alexey G. Sergeev   +5 more
wiley   +1 more source

Palladium-Catalyzed Oxidation of β-C(sp3)-H Bonds of Primary Alkylamines through a Rare Four-Membered Palladacycle Intermediate. [PDF]

, 2020
Site-selective functionalizations of C-H bonds are often achieved with a directing group that leads to five- or six-membered metallacyclic intermediates. Analogous reactions that occur through four-membered metallacycles are rare. We report a challenging
Bunescu, Ala, Ernst, Martin, Hartwig, John F, Qiu, Yehao, Su, Bo, Zuend, Stephan J   +5 more
core   +1 more source

G-arylated hydrogen-bonded cyclic tetramer assemblies with remarkable thermodynamic and kinetic stability [PDF]

, 2015
The preparation and self-assembly of novel G-C dinucleoside monomers that are equipped with electron-poor aryl groups at the G-N2 amino group have been studied.
Alfredo Sanz, Amenta V., Ana M. López-Pérez, Blight B. A., Camacho-García J., Carlos Montoro-García, David González-Rodríguez, Davis J. T., Diederich F., Dong Z., Ercolani G., Gloe K., Gokel G. W., Gong B., González-Rodríguez D., González-Rodríguez D., Hartwig J. F., Hunter C. A., Hwang I.-W., Höger S., Iyoda M., Jorge Camacho-García, Kudernac T., María José Mayoral, Newmark R. A., Nuckolls C., Ohkawa H., Orentas E., Sessler J. L., Shimizu L. S., Sivakova S., Sonia Romero-Pérez, Western E. C., Würthner F., Yang B. H., Yang Y., Zerdan R. B.   +36 more
core   +3 more sources

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, EarlyView.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

Remote-carbonyl-directed sequential Heck/isomerization/C(sp2)–H arylation of alkenes for modular synthesis of stereodefined tetrasubstituted olefins

Nature Communications
Modular and regio-/stereoselective syntheses of all-carbon tetrasubstituted olefins from simple alkene materials remain a challenging project. Here, we demonstrate that a remote-carbonyl-directed palladium-catalyzed Heck/isomerization/C(sp2)–H arylation ...
Runze Luan, Ping Lin, Kun Li, Yu Du, Weiping Su   +4 more
doaj   +1 more source

Enantioselective benzylic C–H arylation via photoredox and nickel dual catalysis

Nature Communications, 2019
Chiral 1,1-diaryl alkanes are important targets in pharmaceutical industry. Here, the authors report report a redox-neutral enantioselective benzylic C−H bond arylation via photoredox/nickel dual catalysis accessing chiral 1,1-diarylalkane compounds ...
Xiaokai Cheng, Huangzhe Lu, Zhan Lu
doaj   +1 more source

Design and synthesis of palladium (II) OCO pincer type complexes and their catalytic role towards the α-arylation of ketones

Journal of Saudi Chemical Society, 2019
Twelve OCO bisacetamide ligands 4aa-4dc were synthesized after condensation of isophenylenediamines 1a-1d and anhydride/acyl chlorides. The corresponding Pd(II)–OCO–H(5aa-5ac), Pd(II)–OCO–Me(5ba-5bc), Pd(II)–OCO–OMe(5ca-5 cc), Pd(II)–OCO–NO2(5da-5dc ...
Wang Kai, Hua Qian, Dabin Liu, Zhiwen Ye
doaj   +1 more source

Synthesis of quaternary aryl phosphonium salts: photoredox-mediated phosphine arylation [PDF]

, 2016
We report a synthesis method for the construction of quaternary aryl phoshonium salts at ambient temperature. The regiospecific reaction invovles the coupling of phosphines with aryl radicals derived from diaryliodonium salts under photoredox ...
A. F. Fearnley, Bayne, Bayne, Bentrude, Cano-yelo, Cano-yelo, Caputo, Cassity, Coa, Dunn, Enders, Fañanás-Mastral, Fumagalli, Gerritsma, He, He, Heng, Hoffman, Horner, Hounjet, Hwang, J. An, Kalyani, Kampmeier, Liu, M. Jackson, Malmgren, Manabe, Marcoux, Marcoux, McNulty, McNulty, McNulty, McNulty, McNulty, McNulty, Merritt, Merzougui, Muneer, Neufeldt, P. Lindovska, Perez, Prier, Ptitsyna, Pérez, Pérez, R. M. Denton, Redmund, Reichl, Rideout, Rideout, Shirakawa, Shirakawa, Smith, Sundalam, Tappe, Tobisu, Tucker, vom Stein, Wang, Werner, Xi, Xiong, Xu, Yusubov, Zhdankin, Zhu   +66 more
core   +2 more sources