Results 51 to 60 of about 311,495 (219)

2-Amino-4,6-dimethoxypyrimidin-1-ium p-toluenesulfonate

Acta Crystallographica Section E, 2011
In the title salt, C6H10N3O2+·C7H7O3S−, the 2-amino-4,6-dimethoxypyrimidinium cation interacts with the sulfonate group of the p-toluenesulfonate anion via a pair of N—H...O hydrogen bonds, forming a cyclic hydrogen-bonded ...
Packianathan Thomas Muthiah, Sundaramoorthy Gomathi   +1 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Crystal structure of 2-methyl-N-[(4-methylpyridin-2-yl)carbamothioyl]benzamide

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C15H15N3OS, there is an intramolecular N—H...O hydrogen bond and an intramolecular C—H...S hydrogen bond involving the C=O and C=S bonds which lie on opposite sides of the molecule.
Nadiah Ameram, Farook Adam, Nur Nadia Fatihah, Salih Al-Juaid   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

2-(3-Benzoylthioureido)-3-phenylpropanoic acid

IUCrData, 2016
In the title compound, C17H16N2O3S, the phenylpropanoic acid and the benzoyl moieties adopt a cis–trans conformation, respectively, with respect to the thiono S atom across the C—N bonds.
Yan Yi Chong, Mohamed Ibrahim Mohamed Tahir, Mohammad B. Kassim   +2 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

1-(2-Chlorobenzoyl)-3-(3-methoxyphenyl)thiourea

Acta Crystallographica Section E, 2013
The title compound, C15H13ClN2O2S, exists in the solid state in its thione form with typical thiourea C—S and C—O bonds lengths as well as shortened C—N bonds.
Amin Badshah, Masahiro Ebihara, M. Khawar Rauf   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Methyl 2-{[3-(4,6-dimethoxypyrimidin-2-yl)ureido]sulfonylmethyl}benzoate

Acta Crystallographica Section E, 2008
In the title compound, C16H18N4O7S, a synthetic sulfonylurea herbicide, there are intramolecular N—H...N and C—H...O hydrogen bonds. Intermolecular N—H...O and C—H...O hydrogen bonds form centrosymmetric dimers. The dihedral angle
Deng-yu Wu, Da-sheng Yu, Li-he Yin, Fang-shi Li, Jin-yun Xia   +4 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source