Results 31 to 40 of about 459,122 (273)

C-di-GMP Pathway in Biomining Bacteria

Advanced Materials Research, 2009
Acidithiobacillus ferrooxidans, A. thiooxidans, and A. caldus are acidophilic Gram-negative -proteobacteria involved in the bioleaching of metal sulfides. Bacterial attachment to mineral surface and biofilm development play a pivotal role in this process.
Castro, M., Ruiz, L. M., Barriga, A., Jerez, C. A., Holmes, D., Guiliani, N.   +5 more
openaire   +6 more sources

Autoinducer-2 and bile salts induce c-di-GMP synthesis to repress the T3SS via a T3SS chaperone

Nature Communications, 2022
Cyclic di-GMP (c-di-GMP) transduces extracellular stimuli into intracellular responses, coordinating a plethora of important biological processes. Low levels of c-di-GMP are often associated with highly virulent behavior that depends on the type III ...
Shuyu Li, Hengxi Sun, Jianghan Li, Yujiao Zhao, Ruiying Wang, Lei Xu, Chongyi Duan, Jialin Li, Zhuo Wang, Qinmeng Liu, Yao Wang, S. Ouyang, Xihui Shen, Lei Zhang   +13 more
semanticscholar   +1 more source

Single Molecule Studies of the c-di-GMP Riboswitch [PDF]

Biophysical Journal, 2011
Cyclic diguanylate (c-di-GMP) is a second messenger signaling molecule important for the regulation of many bacterial processes, including virulence, motility, and biofilm formation. Recent developments have shown that c-di-GMP is recognized by a riboswitch, an mRNA domain that controls gene expression in response to varying concentrations of a target ...
Sharla Wood, Adrian R. Ferré-D'Amaré, Adrian R. Ferré-D'Amaré, David Rueda, Nadia Kulshina   +4 more
openaire   +2 more sources

Impact of c-di-GMP on the Extracellular Proteome of Rhizobium etli

Biology, 2022
Extracellular matrix components of bacterial biofilms include biopolymers such as polysaccharides, nucleic acids and proteins. Similar to polysaccharides, the secretion of adhesins and other matrix proteins can be regulated by the second messenger cyclic diguanylate (cdG). We have performed quantitative proteomics to determine the extracellular protein
María J. Lorite, Ariana Casas-Román, Lourdes Girard, Sergio Encarnación, Natalia Díaz-Garrido, Josefa Badía, Laura Baldomá, Daniel Pérez-Mendoza, Juan Sanjuán   +8 more
openaire   +5 more sources

Evolution of a σ–(c-di-GMP)–anti-σ switch [PDF]

Proceedings of the National Academy of Sciences, 2021
SignificanceDiverse bacterial lifestyle transitions are controlled by the nucleotide second messenger c-di-GMP, including virulence, motility, and biofilm formation. To control such fundamentally distinct processes, the set of genes under c-di-GMP control must have gone through several shifts during bacterial evolution.
Maria A. Schumacher, Kelley A. Gallagher, Neil A. Holmes, Govind Chandra, Max Henderson, David T. Kysela, Richard G. Brennan, Mark J. Buttner   +7 more
openaire   +3 more sources

Interaction between the type 4 pili machinery and a diguanylate cyclase fine-tune c-di-GMP levels during early biofilm formation

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Type 4 pili (T4P) of Pseudomonas aeruginosa are important for surface sensing and regulating intracellular c-di-GMP levels during biofilm formation.
Shanice S. Webster, Calvin K. Lee, William C. Schmidt, G. Wong, G. O’Toole   +4 more
semanticscholar   +1 more source

Identification and Characterization of c-di-GMP Metabolic Enzymes of Leptospira interrogans and c-di-GMP Fluctuations After Thermal Shift and Infection [PDF]

Frontiers in Microbiology, 2018
Leptospirosis is a widespread zoonotic disease caused by pathogenic Leptospira species. The most common species, Leptospira interrogans, can transfer from contaminated soil or water to the human body. It is able to survive these changing environments through sensing and responding to the changes of environmental cues.
Guohui Xiao, Liangliang Kong, Liangliang Kong, Rongbo Che, Yusi Yi, Qinchao Zhang, Jie Yan, Jie Yan, Xu'ai Lin, Xu'ai Lin   +9 more
openaire   +4 more sources

Role of the Transcriptional Regulator ArgR in the Connection between Arginine Metabolism and c-di-GMP Signaling in Pseudomonas putida

Applied and Environmental Microbiology, 2022
Identifying the molecular mechanisms by which metabolic and environmental signals influence the turnover of the second messenger c-di-GMP is key to understanding the regulation of bacterial lifestyles.
Laura Barrientos-Moreno, M. A. Molina-Henares, M. Ramos-González, M. Espinosa-Urgel   +3 more
semanticscholar   +1 more source

c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae

Nature Communications, 2020
Biofilm formation by Vibrio cholerae facilitates environmental persistence, and hyperinfectivity within the host. Biofilm formation is regulated by 3’,5’-cyclic diguanylate (c-di-GMP) and requires production of the type IV mannose-sensitive hemagglutinin
K. A. Floyd, Calvin K. Lee, W. Xian, Mahmoud Nametalla, A. Valentine, Benjamin Crair, Shiwei Zhu, Hannah Q. Hughes, J. Chlebek, Daniel C Wu, Jin Hwan Park, Ali M. Farhat, Charles J. Lomba, Courtney K. Ellison, Y. Brun, J. Campos-Gómez, A. Dalia, Jun Liu, N. Biais, G. Wong, F. Yildiz   +20 more
semanticscholar   +1 more source

The Wsp chemosensory system modulates c-di-GMP-dependent biofilm formation by integrating DSF quorum sensing through the WspR-RpfG complex in Lysobacter

npj Biofilms and Microbiomes, 2022
The ubiquitous Wsp (wrinkly spreader phenotype) chemosensory system and DSF (diffusible signal factor) quorum sensing are two important chemically associated signaling systems that mediate bacterial communications between the host and environment ...
Kangwen Xu, Limin Wang, Dan Xiong, Hongjun Chen, Xinru Tong, Xiaolong Shao, Tao Li, Guoliang Qian   +7 more
semanticscholar   +1 more source