Results 51 to 60 of about 24,065 (296)

Functional diversity of c-di-GMP receptors in prokaryotic and eukaryotic systems

Cell Communication and Signaling, 2023
Cyclic bis-(3', 5')-dimeric guanosine monophosphate (c-di-GMP) is ubiquitous in many bacterial species, where it functions as a nucleotide-based secondary messenger and is a vital regulator of numerous biological processes.
Fazlurrahman Khan, Geum-Jae Jeong, Nazia Tabassum, Young-Mog Kim   +3 more
doaj   +1 more source

Occurrence of Cyclic di-GMP-Modulating Output Domains in Cyanobacteria: an Illuminating Perspective

mBio, 2013
Microorganisms use a variety of metabolites to respond to external stimuli, including second messengers that amplify primary signals and elicit biochemical changes in a cell. Levels of the second messenger cyclic dimeric GMP (c-di-GMP) are regulated by a
Marco Agostoni, Benjamin J. Koestler, Christopher M. Waters, Barry L. Williams, Beronda L. Montgomery   +4 more
doaj   +1 more source

Analysis of Pseudomonas aeruginosa c-di-GMP High and Low Subpopulations Using Flow-assisted Cell Sorting (FACS) and Quantitative Reverse Transcriptase PCR (qRT-PCR)

Bio-Protocol, 2021
Cyclic diguanylate monophosphate (c-di-GMP) is a second messenger signaling molecule that drives the transition from planktonic to the biofilm mode of growth in many bacterial species.
Catherine Armbruster, Matthew Parsek
doaj   +1 more source

c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae. [PDF]

, 2020
Biofilm formation by Vibrio cholerae facilitates environmental persistence, and hyperinfectivity within the host. Biofilm formation is regulated by 3',5'-cyclic diguanylate (c-di-GMP) and requires production of the type IV mannose-sensitive hemagglutinin
Biais, Nicolas, Brun, Yves V, Campos-Gomez, Javier, Chlebek, Jennifer L, Crair, Benjamin, Dalia, Ankur B, Ellison, Courtney K, Farhat, Ali M, Floyd, Kyle A, Hughes, Hannah Q, Hwan Park, Jin, Lee, Calvin K, Liu, Jun, Lomba, Charles J, Nametalla, Mahmoud, Valentine, Aneesa, Wong, Gerard CL, Wu, Daniel C, Xian, Wujing, Yildiz, Fitnat H, Zhu, Shiwei   +20 more
core   +2 more sources

Pleiotropic Effects of c-di-GMP Content in Pseudomonas syringae [PDF]

Applied and Environmental Microbiology, 2019
The present work comprehensively analyzed the transcriptome and phenotypes that were regulated by c-di-GMP in P. syringae . Given that the majority of diguanylate cyclases and phosphodiesterases have not been characterized in P.
Tingting Wang, Zhao Cai, Xiaolong Shao, Weitong Zhang, Yingpeng Xie, Yingchao Zhang, Canfeng Hua, Stephan C. Schuster, Liang Yang, Xin Deng   +9 more
openaire   +3 more sources

Responses to elevated c-di-GMP levels in mutualistic and pathogenic plant-interacting bacteria. [PDF]

PLoS ONE, 2014
Despite a recent burst of research, knowledge on c-di-GMP signaling pathways remains largely fragmentary and molecular mechanisms of regulation and even c-di-GMP targets are yet unknown for most bacteria.
Daniel Pérez-Mendoza, Isabel M Aragón, Harold A Prada-Ramírez, Lorena Romero-Jiménez, Cayo Ramos, María-Trinidad Gallegos, Juan Sanjuán   +6 more
doaj   +1 more source

Flagellar stators stimulate c-di-GMP production by Pseudomonas aeruginosa [PDF]

Journal of Bacteriology, 2018
AbstractFlagellar motility is critical for surface attachment and biofilm formation in many bacteria. A key regulator of flagellar motility in Pseudomonas aeruginosa and other microbes is cyclic diguanylate (c-di-GMP). High levels of this second messenger repress motility and stimulate biofilm formation.
Baker, A, Webster, S, Diepold, A, Kuchma, S, Bordeleau, E, Armitage, J, O'Toole, G   +6 more
openaire   +3 more sources

Cyclic di-GMP regulates bacterial colonization and further biocontrol efficacy of Bacillus velezensis against apple ring rot disease via its potential receptor YdaK

Frontiers in Microbiology, 2022
Bacillus species are among the most investigated beneficial bacteria and widely used in agricultural systems as biological control agents. Its biocontrol efficacy is controlled by diverse regulators.
Huiling Gong, Wenxiao Jiang, Yang Yang, Yue Zhang, Xufei Chen, Wei Li, Panlei Yang, Zhenshuo Wang, Qi Wang, Yan Li   +9 more
doaj   +1 more source

Gas and light: triggers of c-di-GMP-mediated regulation

FEMS Microbiology Reviews, 2023
AbstractThe widespread bacterial second messenger c-di-GMP is responsible for regulating many important physiological functions such as biofilm formation, motility, cell differentiation, and virulence. The synthesis and degradation of c-di-GMP in bacterial cells depend, respectively, on diguanylate cyclases and c-di-GMP-specific phosphodiesterases ...
Zhaoqing Yu, Wei Zhang, He Yang, Shan-Ho Chou, Michael Y Galperin, Jin He   +5 more
openaire   +2 more sources

The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex

Nucleic Acids Research, 2017
Streptomyces are ubiquitous soil bacteria that undergo a complex developmental transition coinciding with their production of antibiotics. This transition is controlled by binding of a novel tetrameric form of the second messenger, 3΄-5΄ cyclic diguanylic acid (c-di-GMP) to the master repressor, BldD.
Schumacher, Maria A., Zeng, Wenjie, Findlay, Kim C., Buttner, Mark J., Brennan, Richard G., Tschowri, Natalia   +5 more
openaire   +2 more sources