Results 51 to 60 of about 31,009,639 (254)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Frontiers in Microbiology, 2018 C-di-GMP has been well investigated to play significant roles in the physiology of many Gram-negative bacteria. However, its effect on Gram-positive bacteria is less known.
Yang Fu +7 more
doaj +1 more source
mBio, 2022 Myxococcus xanthus has a nutrient-regulated biphasic life cycle forming predatory swarms in the presence of nutrients and spore-filled fruiting bodies in the absence of nutrients.
Sofya Kuzmich +6 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur +10 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
mBio, 2017 The bacterial second messenger bis-(3′-5′)-cyclic diguanosine monophosphate (c-di-GMP) ubiquitously promotes bacterial biofilm formation. Intracellular pools of c-di-GMP seem to be dynamically negotiated by diguanylate cyclases (DGCs, with GGDEF domains)
Olga Sarenko +7 more
doaj +1 more source
The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways [PDF]
, 2012 The genetic adaptation of pathogens in host tissue plays a key role in the establishment of chronic infections. While whole genome sequencing has opened up the analysis of genetic changes occurring during long-term infections, the identification and ...
Tina Jaeger (158216) +57 more
core +1 more source
Biomass DNA: An Emerging Building Block for Advanced Materials
Advanced Materials, EarlyView.Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
Cell ReportsSummary: Cyclic di-guanosine monophosphate (c-di-GMP) is a bacterial second messenger that governs the lifestyle switch between planktonic and biofilm states.
Corey Kennelly +2 more
doaj +1 more source
c-di-GMP specifically and significantly enhances RavS-RavR phosphotransfer.
, 2019 (a) c-di-GMP enhances RavS-RavR phosphotransfer in vitro. A total of 5 μM RavSΔN was autophosphorylated for 15 min by the addition of 10 μCi [γ-32P]ATP. A total of 15 μM RavRΔEAL or RavRΔEAL(D496A) was added and incubated for 30 min at 25°C.
Shou-Ting Cheng (7225043) +2 more
core +1 more source