Results 61 to 70 of about 31,009,639 (254)

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

The Multiple Regulatory Relationship Between RNA-Chaperone Hfq and the Second Messenger c-di-GMP

Frontiers in Microbiology, 2021
RNA chaperone protein Hfq is an important post-transcriptional regulator in bacteria, while c-di-GMP is a second messenger signaling molecule widely distributed in bacteria.
Yang Fu, Yang Fu, Zhaoqing Yu, Li Zhu, Zhou Li, Wen Yin, Xiaodong Shang, Shan-Ho Chou, Qi Tan, Jin He   +9 more
doaj   +1 more source

Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges

Advanced Robotics Research, EarlyView.
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley   +1 more source

Image3_Identification and Characterization of c-di-GMP Metabolic Enzymes of Leptospira interrogans and c-di-GMP Fluctuations After Thermal Shift and Infection.TIF

, 2018
Leptospirosis is a widespread zoonotic disease caused by pathogenic Leptospira species. The most common species, Leptospira interrogans, can transfer from contaminated soil or water to the human body.
Xu'ai Lin (5124974), Qinchao Zhang (5124971), Liangliang Kong (478500), Jie Yan (119530), Guohui Xiao (3529880), Rongbo Che (518169), Yusi Yi (5124977)   +6 more
core   +1 more source

The PilZ_Δ107-117-FimX_GGDEF-EAL-c-di-GMP complex.

, 2021
A and B) Ribbon representations of the two main modes of contact observed in the crystal lattice of the PilZΔ107-117-FimXGGDEF-EAL-c-di-GMP complex. PilZΔ107–117 is colored blue and FimXGGDEF-EAL colored magenta. A: PilZ-FimX interface 1.
Chuck S. Farah (6716723), Cristiane R. Guzzo (11278921), William Cenens (282027), Denize C. Favaro (1975516), Germán G. Sgro (6716702), Edgar E. Llontop (7252868), Roberto K. Salinas (221476)   +6 more
core   +1 more source

UC Food Waste: A Multimodal Robotic Perception Dataset for Robust Contaminant Detection in Complex Biowaste Scenes

Advanced Robotics Research, EarlyView.
A balanced multimodal food‐waste dataset and a novel Split Spatial‐Spectral Attention fusion framework are presented for robotic contaminant detection. Separate processing of RGB, thermal, and multispectral inputs preserves subtle material signatures before feature integration, reducing modality interference and improving classification and ...
Matthew Vestal, James Ireland, David Hinwood, Xing Wang, Min Wang, Damith Herath   +5 more
wiley   +1 more source

Image4_Identification and Characterization of c-di-GMP Metabolic Enzymes of Leptospira interrogans and c-di-GMP Fluctuations After Thermal Shift and Infection.TIF

, 2018
Leptospirosis is a widespread zoonotic disease caused by pathogenic Leptospira species. The most common species, Leptospira interrogans, can transfer from contaminated soil or water to the human body.
Xu'ai Lin (5124974), Qinchao Zhang (5124971), Liangliang Kong (478500), Jie Yan (119530), Guohui Xiao (3529880), Rongbo Che (518169), Yusi Yi (5124977)   +6 more
core   +1 more source

DataSheet_1_Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model.pdf

, 2022
Pertussis, caused by the gram-negative bacterium Bordetella pertussis, is a highly contagious respiratory disease. Intranasal vaccination is an ideal strategy to prevent pertussis, as the nasal mucosa represents the first-line barrier to B.
Yuhao Su (12409693), Mingbo Sun (6437429), Jiangli Liang (10741002), Wenwen Jiang (1758571), Qin Gu (499256), Li Shi (174141), Lukui Cai (11602006), Xiaoyu Wang (182979), Jingyan Li (1955116)   +8 more
core   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Image5_Identification and Characterization of c-di-GMP Metabolic Enzymes of Leptospira interrogans and c-di-GMP Fluctuations After Thermal Shift and Infection.TIF

, 2018
Leptospirosis is a widespread zoonotic disease caused by pathogenic Leptospira species. The most common species, Leptospira interrogans, can transfer from contaminated soil or water to the human body.
Xu'ai Lin (5124974), Qinchao Zhang (5124971), Liangliang Kong (478500), Jie Yan (119530), Guohui Xiao (3529880), Rongbo Che (518169), Yusi Yi (5124977)   +6 more
core   +1 more source