Results 41 to 50 of about 24,065 (296)
Frontiers in Cellular and Infection Microbiology, 2017 Cyclic-di-GMP (c-di-GMP) is an intracellular secondary messenger which controls the biofilm life cycle in many bacterial species. High intracellular c-di-GMP content enhances biofilm formation via the reduction of motility and production of biofilm ...
Song Lin Chua +13 more
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Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer [PDF]
, 2017 Coordination of cell movement with cell differentiation is a major feat of embryonic development. The Dictyostelium stalk always forms at the organizing tip, by a mechanism that is not understood. We previously reported that cyclic diguanylate (c-di-GMP),
Chen +15 more
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Detection of c-di-GMP-Responsive DNA Binding [PDF]
, 2017 Modulation of signal transduction via binding of the secondary messenger molecule cyclic di-GMP to effector proteins is a near universal regulatory schema in bacteria. In particular, direct binding of c-di-GMP to transcriptional regulators has been shown to alter gene expression of a variety of processes.
Jacob R, Chambers, Karin, Sauer
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You’ve come a long way: c-di-GMP signaling [PDF]
Current Opinion in Microbiology, 2012 Cyclic dimeric guanosine monophosphate (c-di-GMP) is a common, bacterial second messenger that regulates diverse cellular processes in bacteria. Opposing activities of diguanylate cyclases (DGCs) and phosphodiesterases (PDEs) control c-di-GMP homeostasis in the cell.
Holger, Sondermann +2 more
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New insights into Legionella pneumophila biofilm regulation by c-di-GMP signaling [PDF]
, 2016 The waterborne pathogen Legionella pneumophila grows as a biofilm, freely or inside amoebae. Cyclic-di-GMP (c-di-GMP), a bacterial second messenger frequently implicated in biofilm formation, is synthesized and degraded by diguanylate cyclases (DGCs) and
Allombert, Julie +5 more
core +3 more sources
Frontiers in Microbiology, 2020 3′,5′ Cyclic diguanylic acid (c-di-GMP) has been shown to play a central role in the regulation of bacterial physiological processes such as biofilm formation and virulence production, and is regarded as a potential target for the development of anti ...
Teng-Fei Xuan +4 more
doaj +1 more source
Identification of the YfgF MASE1 domain as a modulator of bacterial responses to aspartate [PDF]
, 2013 Complex 3'-5'-cyclic diguanylic acid (c-di-GMP) responsive regulatory networks that are modulated by the action of multiple diguanylate cyclases (DGC; GGDEF domain proteins) and phosphodiesterases (PDE; EAL domain proteins) have evolved in many bacteria.
Agasing, A. +3 more
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A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa [PDF]
, 2018 Nutrients such as amino acids play key roles in shaping the metabolism of microorganisms in natural environments and in host–pathogen interactions.
Cutruzzolà, F. +8 more
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Evolution of a σ–(c-di-GMP)–anti-σ switch [PDF]
Proceedings of the National Academy of Sciences, 2021 SignificanceDiverse bacterial lifestyle transitions are controlled by the nucleotide second messenger c-di-GMP, including virulence, motility, and biofilm formation. To control such fundamentally distinct processes, the set of genes under c-di-GMP control must have gone through several shifts during bacterial evolution.
Maria A. Schumacher +7 more
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One‐Flask Synthesis of Cyclic Diguanosine Monophosphate (c‐di‐GMP) [PDF]
Current Protocols in Nucleic Acid Chemistry, 2012 AbstractThe bacterial signaling molecule, cyclic diguanosine monophosphate (c‐di‐GMP), plays a key role in controlling biofilm formation and pathogenic virulence, among many other functions. It has widespread consequences for human health, and current research is actively exploring its molecular mechanisms.
Barbara L, Gaffney, Roger A, Jones
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