Results 41 to 50 of about 31,009,639 (254)

Analysis of Pseudomonas aeruginosa c-di-GMP High and Low Subpopulations Using Flow-assisted Cell Sorting (FACS) and Quantitative Reverse Transcriptase PCR (qRT-PCR)

open access: yesBio-Protocol, 2021
Cyclic diguanylate monophosphate (c-di-GMP) is a second messenger signaling molecule that drives the transition from planktonic to the biofilm mode of growth in many bacterial species.
Catherine Armbruster, Matthew Parsek
doaj   +1 more source

Formation and dimerization of the phosphodiesterase active site of the Pseudomonas aeruginosa MorA, a bi-functional c-di-GMP regulator

open access: yes, 2014
Diguanylate cyclases (DGC) and phosphodiesterases (PDE) respectively synthesise and hydrolyse the secondary messenger cyclic dimeric GMP (c-di-GMP), and both activities are often found in a single protein.
Mikolajek, Halina   +5 more
core   +1 more source

Outer membrane vesicles induce the mussel plantigrade settlement via regulation of c-di-GMP

open access: yes, 2023
Despite the importance of outer membrane vesicles (OMVs) in benthic animal settlement, the underlying molecular mechanism remains elusive. Here, the impact of OMVs and OMVs synthesis-related tolB gene in Mytilus coruscus plantigrade settlement was tested.
Guanju Wu (16248608)   +6 more
core   +1 more source

Responses to elevated c-di-GMP levels in mutualistic and pathogenic plant-interacting bacteria. [PDF]

open access: yesPLoS ONE, 2014
Despite a recent burst of research, knowledge on c-di-GMP signaling pathways remains largely fragmentary and molecular mechanisms of regulation and even c-di-GMP targets are yet unknown for most bacteria.
Daniel Pérez-Mendoza   +6 more
doaj   +1 more source

Image1_FleQ, FleN and c-di-GMP coordinately regulate cellulose production in Pseudomonas syringae pv. tomato DC3000.TIF

open access: yes, 2023
The second messenger cyclic di-GMP (c-di-GMP) controls the transition between motility and sessility in many bacterial species by a variety of mechanisms, including the production of multiple exopolysaccharides. Pseudomonas syringae pv.
María-Trinidad Gallegos (535322)   +9 more
core   +1 more source

DataSheet1_Visualization of c-di-GMP in multicellular Dictyostelium stages.pdf

open access: yes, 2023
The bacterial signaling molecule cyclic diguanosine monophosphate (c-di-GMP) is only synthesized and utilized by the cellular slime mold Dictyostelium discoideum among eukaryotes.
Yusuke V. Morimoto (11527207)   +2 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Cyclic di-GMP regulates bacterial colonization and further biocontrol efficacy of Bacillus velezensis against apple ring rot disease via its potential receptor YdaK

open access: yesFrontiers in Microbiology, 2022
Bacillus species are among the most investigated beneficial bacteria and widely used in agricultural systems as biological control agents. Its biocontrol efficacy is controlled by diverse regulators.
Huiling Gong   +9 more
doaj   +1 more source

Changes in c-di-GMP riboswitch-controlled gene expression resulting from increased intracellular c-di-GMP in Clostridioides difficile strain 630Δerm.

open access: yes, 2021
Changes in c-di-GMP riboswitch-controlled gene expression resulting from increased intracellular c-di-GMP in Clostridioides difficile strain 630Δerm.
Roberto M. La Ragione (8733108)   +5 more
core   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

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