Results 21 to 30 of about 17,994 (250)

Systematic Identification of Cyclic-di-GMP Binding Proteins in Vibrio cholerae Reveals a Novel Class of Cyclic-di-GMP-Binding ATPases Associated with Type II Secretion Systems. [PDF]

open access: yesPLoS Pathogens, 2015
Cyclic-di-GMP (c-di-GMP) is a ubiquitous bacterial signaling molecule that regulates a variety of complex processes through a diverse set of c-di-GMP receptor proteins.
Kevin G Roelofs   +8 more
doaj   +1 more source

Quorum-Sensing Master Regulator VfmE Is a c-di-GMP Effector That Controls Pectate Lyase Production in the Phytopathogen Dickeya dadantii

open access: yesMicrobiology Spectrum, 2022
Dickeya dadantii is a phytopathogenic bacterium that causes diseases on a wide range of host plants. The pathogen secretes pectate lyases (Pel) through the type II secretion system (T2SS) that degrades the cell wall in host plants.
Biswarup Banerjee   +5 more
doaj   +1 more source

Identification of Cyclic-di-GMP-Modulating Protein Residues by Bidirectionally Evolving a Social Behavior in Pseudomonas fluorescens

open access: yesmSystems, 2022
Modulation of the intracellular cyclic di-GMP (c-di-GMP) pool is central to the formation of structured bacterial communities. Genome annotations predict the presence of dozens of conserved c-di-GMP catalytic enzymes in many bacterial species, but the ...
Collin Kessler, Wook Kim
doaj   +1 more source

Visualization of c-di-GMP in multicellular Dictyostelium stages

open access: yesFrontiers in Cell and Developmental Biology, 2023
The bacterial signaling molecule cyclic diguanosine monophosphate (c-di-GMP) is only synthesized and utilized by the cellular slime mold Dictyostelium discoideum among eukaryotes. Dictyostelium cells undergo a transition from a unicellular to a multicellular state, ultimately forming a stalk and spores.
Hayato Ide   +3 more
openaire   +3 more sources

Thiophosphate Analogs of c-di-GMP: Impact on Polymorphism [PDF]

open access: yesNucleosides, Nucleotides & Nucleic Acids, 2009
Seven phosphorothioate analogs of c-di-GMP (all diastereomers of mono-, di-, and trithiophosphates) were prepared to assess the impact of the thioate substitutions on c-di-GMP polymorphism using 1D (1)H and (31)P NMR, along with 2D NOESY and DOSY, for both the Na(+) and K(+) salts.
Jianwei, Zhao   +4 more
openaire   +2 more sources

Multiple activities of c-di-GMP in Pseudomonas aeruginosa [PDF]

open access: yesNucleic Acids Symposium Series, 2009
Survival strategies of many bacterial pathogens, including Pseudomonas aeruginosa, are linked to their ability to form surface associated communities called biofilms. The biofilm life style allows these organisms to persist in various tissues, avoid clearance by innate host defences and significantly enhanced their resistance to antibiotics.
Stephen, Lory   +2 more
openaire   +2 more sources

A Filter Binding Assay to Quantify the Association of Cyclic di-GMP to Proteins

open access: yesBio-Protocol, 2015
Cyclic di-GMP (c-di-GMP) is a ubiquitous second messenger that regulates many processes in bacteria including biofilm formation, motility, and virulence (Hengge, 2009). Analysis of c-di-GMP binding properties of bacterial proteins is an important step to
Disha Srivastava, Christopher Waters
doaj   +1 more source

Mutant structure of metabolic switch protein in complex with monomeric c-di-GMP reveals a potential mechanism of protein-mediated ligand dimerization

open access: yesScientific Reports, 2023
Bacterial second messengers c-di-GMP and (p)ppGpp have broad functional repertoires ranging from growth and cell cycle control to the regulation of biofilm formation and virulence.
Badri Nath Dubey   +5 more
doaj   +1 more source

Protein Deacetylase CobB Interplays with c-di-GMP [PDF]

open access: yesSSRN Electronic Journal, 2018
Abstract As a ubiquitous bacterial secondary messenger, c-di-GMP plays key regulatory roles in processes such as bacterial motility and transcription regulation. CobB is the Sir2 family protein deacetylase that controls energy metabolism, chemotaxis and DNA supercoiling in many bacteria.
Xu, Zhaowei   +15 more
openaire   +1 more source

Evolution of a σ–(c-di-GMP)–anti-σ switch [PDF]

open access: yesProceedings of the National Academy of Sciences, 2021
Significance Diverse bacterial lifestyle transitions are controlled by the nucleotide second messenger c-di-GMP, including virulence, motility, and biofilm formation. To control such fundamentally distinct processes, the set of genes under c-di-GMP control must have gone through several shifts during bacterial ...
Maria A. Schumacher   +7 more
openaire   +2 more sources

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