Scientific Reports, 2023 Bacterial second messengers c-di-GMP and (p)ppGpp have broad functional repertoires ranging from growth and cell cycle control to the regulation of biofilm formation and virulence.
Badri Nath Dubey +5 more
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Principles of c-di-GMP signaling : characterization of a second messenger system orchestrating bacterial life style [PDF]
, 2007 Bacteria are able to switch between two mutually exclusive lifestyles, motile single cells and sedentary multicellular communities, known as biofilms, that colonize surfaces.
Christen, Beat
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Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking [PDF]
, 2016 Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch ...
Fucile, Geoffrey +20 more
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mSphere, 2018 The intracellular signaling molecule cyclic diguanylate (c-di-GMP) regulates many processes in bacteria, with a central role in controlling the switch between motile and nonmotile lifestyles.
Robert W. McKee +2 more
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Systematic Analysis of c-di-GMP Signaling Mechanisms and Biological Functions in
mBio, 2020 Dickeya zeae is an important and aggressive bacterial phytopathogen that can cause substantial economic losses in banana and rice plantations. We previously showed that c-di-GMP signaling proteins (cyclases/phosphodiesterases) in D.
Yufan Chen +5 more
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Microbiology Spectrum, 2023 Dickeya dadantii is a Gram-negative bacterium that causes soft rot diseases in a variety of plants. This pathogen secretes pectate lyase (Pel) enzymes to degrade the plant cell wall, a process controlled by the bacterial second messenger cyclic ...
Biswarup Banerjee +2 more
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Analysis of cyclic di-GMP signaling components in "caulobacter crescentus" behavior and cell cycle control [PDF]
, 2013 Cell cycle progression and polar morphogenesis in Caulobacter crescentus are coordinated by the interplay of multiple proteins in time and space. One major regulatory factor is the second messenger cyclic di-GMP (c-di-GMP) therefore especially the ...
Friedrich, Elvira
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Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence [PDF]
, 2014 Bis-(3',5') cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence. Cyclic di-GMP influences diverse functions through
Caly, Delphine L. +32 more
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Insights into the activation mechanism of PopA, a cyclic di-GMP effector protein involved in cell cycle and development of "Caulobacter Crescentus" [PDF]
, 2012 In Caulobacter crescentus, a complex network integrating cyclic di-GMP and Phosphorylation-dependent signals controls the proteolysis of key regulatory proteins to drive cell cycle and polar morphogenesis.
Schalch-Moser, Annina Larissa
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Endo-S-c-di-GMP Analogues-Polymorphism and Binding Studies with Class I Riboswitch
Molecules, 2012 C-di-GMP, a cyclic guanine dinucleotide, has been shown to regulate biofilm formation as well as virulence gene expression in a variety of bacteria. Analogues of c-di-GMP have the potential to be used as chemical probes to study c-di-GMP signaling and ...
Herman O. Sintim +4 more
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