Results 31 to 40 of about 17,904 (252)

Systematic Analysis of c-di-GMP Signaling Mechanisms and Biological Functions in Dickeya zeae EC1

mBio, 2020
Dickeya zeae is an important and aggressive bacterial phytopathogen that can cause substantial economic losses in banana and rice plantations. We previously showed that c-di-GMP signaling proteins (cyclases/phosphodiesterases) in D.
Yufan Chen, Jianuan Zhou, Mingfa Lv, Zhibin Liang, Matthew R. Parsek, Lian-hui Zhang   +5 more
doaj   +1 more source

Dissecting the molecular dance: c-di-GMP, cAMP-CRP, and VfmH collaboration in pectate lyase regulation for Dickeya dadantii—unveiling the soft rot pathogen’s strategy

Microbiology Spectrum, 2023
Dickeya dadantii is a Gram-negative bacterium that causes soft rot diseases in a variety of plants. This pathogen secretes pectate lyase (Pel) enzymes to degrade the plant cell wall, a process controlled by the bacterial second messenger cyclic ...
Biswarup Banerjee, Xiaochen Yuan, Ching-Hong Yang   +2 more
doaj   +1 more source

C-di-GMP Pathway in Biomining Bacteria

Advanced Materials Research, 2009
Acidithiobacillus ferrooxidans, A. thiooxidans, and A. caldus are acidophilic Gram-negative -proteobacteria involved in the bioleaching of metal sulfides. Bacterial attachment to mineral surface and biofilm development play a pivotal role in this process.
Castro, M., Ruiz, L. M., Barriga, A., Jerez, C. A., Holmes, D., Guiliani, N.   +5 more
openaire   +5 more sources

Reciprocal c-di-GMP signaling: Incomplete flagellum biogenesis triggers c-di-GMP signaling pathways that promote biofilm formation [PDF]

PLOS Genetics, 2020
The assembly status of the V. cholerae flagellum regulates biofilm formation, suggesting that the bacterium senses a lack of movement to commit to a sessile lifestyle. Motility and biofilm formation are inversely regulated by the second messenger molecule cyclic dimeric guanosine monophosphate (c-di-GMP).
Daniel C. Wu, David Zamorano-Sánchez, Fernando A. Pagliai, Jin Hwan Park, Kyle A. Floyd, Calvin K. Lee, Giordan Kitts, Christopher B. Rose, Eric M. Bilotta, Gerard C. L. Wong, Fitnat H. Yildiz   +10 more
openaire   +5 more sources

Endo-S-c-di-GMP Analogues-Polymorphism and Binding Studies with Class I Riboswitch

Molecules, 2012
C-di-GMP, a cyclic guanine dinucleotide, has been shown to regulate biofilm formation as well as virulence gene expression in a variety of bacteria. Analogues of c-di-GMP have the potential to be used as chemical probes to study c-di-GMP signaling and ...
Herman O. Sintim, Nirmal Pahadi, Jingxin Wang, David A. Sayre, Jie Zhou   +4 more
doaj   +1 more source

Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa: a connection between quorum sensing and c-di-GMP [PDF]

Scientific Reports, 2018
AbstractTo address the drug-resistance of bacterial pathogens without imposing a selective survival pressure, virulence and biofilms are highly attractive targets. Here, we show that terrein, which was isolated from Aspergillus terreus, reduced virulence factors (elastase, pyocyanin, and rhamnolipid) and biofilm formation via antagonizing quorum ...
Kim, Bomin, Park, Ji-Su, Choi, Ha-Young, Yoon, Sang Sun, Kim, Won-Gon   +4 more
openaire   +3 more sources

A Multimodal Strategy Used By A Large c-di-GMP Network [PDF]

Journal of Bacteriology, 2017
Abstract The Pseudomonas fluorescens genome encodes for 50+ proteins involved in -di-GMP signaling. Here, we demonstrate that when tested across 188 nutrients, these enzymes and effectors appear capable of impacting biofilm formation.
Dahlstrom, Kurt M., Collins, Alan J., Doing, Georgia, Taroni, Jacyln N, Gauvin, Timothy J., Greene, Casey S., Hogan, Deborah A., O’Toole, George A.   +7 more
openaire   +2 more sources

Dual Regulatory Role Exerted by Cyclic Dimeric GMP To Control FsnR-Mediated Bacterial Swimming

mBio, 2022
Bacterial motility has great medical and ecological significance because of its essential role in bacterial survival and pathogenesis. Cyclic dimeric GMP (c-di-GMP), a second messenger in bacteria, is the predominant regulator of flagellar synthesis and ...
Xin Zhang, Yan Wang, Yao Wu, Zhi-Hui Yuan, Zhen Cai, Wei Qian, Xin Ge, Fang-Fang Wang   +7 more
doaj   +1 more source

OpaR Controls the Metabolism of c-di-GMP in Vibrio parahaemolyticus [PDF]

Frontiers in Microbiology, 2021
Vibrio parahaemolyticus, the leading cause of seafood-associated gastroenteritis worldwide, has a strong ability to form biofilms on surfaces. Quorum sensing (QS) is a process widely used by bacteria to communicate with each other and control gene expression via the secretion and detection of autoinducers.
Yiquan Zhang, Yiquan Zhang, Yue Qiu, He Gao, Junfang Sun, Xue Li, Miaomiao Zhang, Xingfan Xue, Wenhui Yang, Bin Ni, Lingfei Hu, Zhe Yin, Renfei Lu, Dongsheng Zhou   +13 more
openaire   +3 more sources

Fluorescent Detection of the Ubiquitous Bacterial Messenger 3′,5′ Cyclic Diguanylic Acid by Using a Small Aromatic Molecule

Frontiers in Microbiology, 2020
3′,5′ Cyclic diguanylic acid (c-di-GMP) has been shown to play a central role in the regulation of bacterial physiological processes such as biofilm formation and virulence production, and is regarded as a potential target for the development of anti ...
Teng-Fei Xuan, Jun Liu, Zi-Qiang Wang, Wei-Min Chen, Jing Lin   +4 more
doaj   +1 more source