Results 31 to 40 of about 24,065 (296)
Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking [PDF]
, 2016 Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch ...
Dubey, Badri N. +6 more
core +2 more sources
C-di-GMP Pathway in Biomining Bacteria
Advanced Materials Research, 2009 Acidithiobacillus ferrooxidans, A. thiooxidans, and A. caldus are acidophilic Gram-negative -proteobacteria involved in the bioleaching of metal sulfides. Bacterial attachment to mineral surface and biofilm development play a pivotal role in this process.
Castro, M. +5 more
openaire +5 more sources
mSphere, 2018 The intracellular signaling molecule cyclic diguanylate (c-di-GMP) regulates many processes in bacteria, with a central role in controlling the switch between motile and nonmotile lifestyles.
Robert W. McKee +2 more
doaj +1 more source
Systematic Analysis of c-di-GMP Signaling Mechanisms and Biological Functions in
mBio, 2020 Dickeya zeae is an important and aggressive bacterial phytopathogen that can cause substantial economic losses in banana and rice plantations. We previously showed that c-di-GMP signaling proteins (cyclases/phosphodiesterases) in D.
Yufan Chen +5 more
doaj +1 more source
Roles of the second messenger cyclic di-GMP in environmental adaptation of Sinorhizobium meliloti [PDF]
, 2017 Bacteria have evolved various systems for the integration of environmental signals to rapidly coordinate cellular pathways and adapt to changes in their environment.
Schäper, Simon
core +1 more source
Thiophosphate Analogs of c-di-GMP: Impact on Polymorphism [PDF]
Nucleosides, Nucleotides & Nucleic Acids, 2009 Seven phosphorothioate analogs of c-di-GMP (all diastereomers of mono-, di-, and trithiophosphates) were prepared to assess the impact of the thioate substitutions on c-di-GMP polymorphism using 1D (1)H and (31)P NMR, along with 2D NOESY and DOSY, for both the Na(+) and K(+) salts.
Jianwei, Zhao +4 more
openaire +2 more sources
Visualization of c-di-GMP in multicellular Dictyostelium stages
Frontiers in Cell and Developmental Biology, 2023 The bacterial signaling molecule cyclic diguanosine monophosphate (c-di-GMP) is only synthesized and utilized by the cellular slime mold Dictyostelium discoideum among eukaryotes. Dictyostelium cells undergo a transition from a unicellular to a multicellular state, ultimately forming a stalk and spores.
Hayato Ide +3 more
openaire +3 more sources
Endo-S-c-di-GMP Analogues-Polymorphism and Binding Studies with Class I Riboswitch
Molecules, 2012 C-di-GMP, a cyclic guanine dinucleotide, has been shown to regulate biofilm formation as well as virulence gene expression in a variety of bacteria. Analogues of c-di-GMP have the potential to be used as chemical probes to study c-di-GMP signaling and ...
Herman O. Sintim +4 more
doaj +1 more source
Multiple activities of c-di-GMP in Pseudomonas aeruginosa [PDF]
Nucleic Acids Symposium Series, 2009 Survival strategies of many bacterial pathogens, including Pseudomonas aeruginosa, are linked to their ability to form surface associated communities called biofilms. The biofilm life style allows these organisms to persist in various tissues, avoid clearance by innate host defences and significantly enhanced their resistance to antibiotics.
Stephen, Lory +2 more
openaire +2 more sources
Dual Regulatory Role Exerted by Cyclic Dimeric GMP To Control FsnR-Mediated Bacterial Swimming
mBio, 2022 Bacterial motility has great medical and ecological significance because of its essential role in bacterial survival and pathogenesis. Cyclic dimeric GMP (c-di-GMP), a second messenger in bacteria, is the predominant regulator of flagellar synthesis and ...
Xin Zhang +7 more
doaj +1 more source