Results 51 to 60 of about 24,734 (337)

Identification of the YfgF MASE1 domain as a modulator of bacterial responses to aspartate [PDF]

open access: yes, 2013
Complex 3'-5'-cyclic diguanylic acid (c-di-GMP) responsive regulatory networks that are modulated by the action of multiple diguanylate cyclases (DGC; GGDEF domain proteins) and phosphodiesterases (PDE; EAL domain proteins) have evolved in many bacteria.
Agasing, A.   +3 more
core   +1 more source

Evolution of a σ–(c-di-GMP)–anti-σ switch [PDF]

open access: yesProceedings of the National Academy of Sciences, 2021
SignificanceDiverse bacterial lifestyle transitions are controlled by the nucleotide second messenger c-di-GMP, including virulence, motility, and biofilm formation. To control such fundamentally distinct processes, the set of genes under c-di-GMP control must have gone through several shifts during bacterial evolution.
Maria A. Schumacher   +7 more
openaire   +2 more sources

Functional diversity of c-di-GMP receptors in prokaryotic and eukaryotic systems

open access: yesCell Communication and Signaling, 2023
Cyclic bis-(3', 5')-dimeric guanosine monophosphate (c-di-GMP) is ubiquitous in many bacterial species, where it functions as a nucleotide-based secondary messenger and is a vital regulator of numerous biological processes.
Fazlurrahman Khan   +3 more
doaj   +1 more source

Analysis of Pseudomonas aeruginosa c-di-GMP High and Low Subpopulations Using Flow-assisted Cell Sorting (FACS) and Quantitative Reverse Transcriptase PCR (qRT-PCR)

open access: yesBio-Protocol, 2021
Cyclic diguanylate monophosphate (c-di-GMP) is a second messenger signaling molecule that drives the transition from planktonic to the biofilm mode of growth in many bacterial species.
Catherine Armbruster, Matthew Parsek
doaj   +1 more source

Responses to elevated c-di-GMP levels in mutualistic and pathogenic plant-interacting bacteria. [PDF]

open access: yesPLoS ONE, 2014
Despite a recent burst of research, knowledge on c-di-GMP signaling pathways remains largely fragmentary and molecular mechanisms of regulation and even c-di-GMP targets are yet unknown for most bacteria.
Daniel Pérez-Mendoza   +6 more
doaj   +1 more source

Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer [PDF]

open access: yes, 2017
Coordination of cell movement with cell differentiation is a major feat of embryonic development. The Dictyostelium stalk always forms at the organizing tip, by a mechanism that is not understood. We previously reported that cyclic diguanylate (c-di-GMP),
Chen   +15 more
core   +3 more sources

Pleiotropic Effects of c-di-GMP Content in Pseudomonas syringae [PDF]

open access: yesApplied and Environmental Microbiology, 2019
The present work comprehensively analyzed the transcriptome and phenotypes that were regulated by c-di-GMP in P. syringae . Given that the majority of diguanylate cyclases and phosphodiesterases have not been characterized in P.
Tingting Wang   +9 more
openaire   +3 more sources

Occurrence of Cyclic di-GMP-Modulating Output Domains in Cyanobacteria: an Illuminating Perspective

open access: yesmBio, 2013
Microorganisms use a variety of metabolites to respond to external stimuli, including second messengers that amplify primary signals and elicit biochemical changes in a cell. Levels of the second messenger cyclic dimeric GMP (c-di-GMP) are regulated by a
Marco Agostoni   +4 more
doaj   +1 more source

Cyclic di-GMP regulates bacterial colonization and further biocontrol efficacy of Bacillus velezensis against apple ring rot disease via its potential receptor YdaK

open access: yesFrontiers in Microbiology, 2022
Bacillus species are among the most investigated beneficial bacteria and widely used in agricultural systems as biological control agents. Its biocontrol efficacy is controlled by diverse regulators.
Huiling Gong   +9 more
doaj   +1 more source

Flagellar stators stimulate c-di-GMP production by Pseudomonas aeruginosa [PDF]

open access: yesJournal of Bacteriology, 2018
AbstractFlagellar motility is critical for surface attachment and biofilm formation in many bacteria. A key regulator of flagellar motility in Pseudomonas aeruginosa and other microbes is cyclic diguanylate (c-di-GMP). High levels of this second messenger repress motility and stimulate biofilm formation.
Baker, A   +6 more
openaire   +3 more sources

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