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para-Selective C–H bond functionalization of iodobenzenes
Chemical Communications, 2016An oxidation-induced strategy forpara-C–H functionalization of iodobenzenes was demonstrated, which provides a general idea for the development of new, highly selectivepara-C–H functionalization reactions.
Ying, Zhao +4 more
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Ag-catalyzed C–H/C–C bond functionalization
Chemical Society Reviews, 2016In this review, we focus on the developments of Ag-catalyzed C–H/C–C bond functionalization and the corresponding mechanism.
Qing-Zhong, Zheng, Ning, Jiao
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Journal of the American Chemical Society, 2010
The ubiquitous Stille coupling reaction utilizes Sn-C bonds and is of great utility to organic chemists. Unlike the B-C bonds used in the Miyaura-Suzuki coupling reaction, which are readily obtained via direct borylation of C-H bonds, routes to organotin compounds via direct C-H bond functionalization are lacking.
Meghan E, Doster +4 more
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The ubiquitous Stille coupling reaction utilizes Sn-C bonds and is of great utility to organic chemists. Unlike the B-C bonds used in the Miyaura-Suzuki coupling reaction, which are readily obtained via direct borylation of C-H bonds, routes to organotin compounds via direct C-H bond functionalization are lacking.
Meghan E, Doster +4 more
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Rhodium-Catalyzed C–H Bond Functionalization with Amides by Double C–H/C–N Bond Activation
Organic Letters, 2016The first C-H bond functionalization with amides as the coupling partners via selective activation of the amide N-C bond using rhodium(I) catalysts under highly chemoselective conditions is reported. Notably, this report constitutes the first catalytic activation of the amide N-C(O) bond by rhodium.
Guangrong, Meng, Michal, Szostak
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Borylation and Silylation of C–H Bonds: A Platform for Diverse C–H Bond Functionalizations
Accounts of Chemical Research, 2011Methods that functionalize C-H bonds can lead to new approaches for the synthesis of organic molecules, but to achieve this goal, researchers must develop site-selective reactions that override the inherent reactivity of the substrates. Moreover, reactions are needed that occur with high turnover numbers and with high tolerance for functional groups if
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Flow Chemistry Perspective for C H Bond Functionalization
2017In this chapter, we give an overview of the use of continuous-flow reactors for C. H activation chemistry.
Laudadio, G., Noël, T.
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Precise Functionalization of Remote C-H Bonds
Chemical Research in Chinese Universities, 2020Remote C-H bond functionalization of arenes with precise control is a recognized extraordinary challenge in organic synthesis. Recently, Yu and Houk et al. developed an elegant strategy to distinguish and functionalize remote Csp2-H bonds of (hetero)arenes within one-bond distance by the interplay of a remote directing template and a transient ...
Zeshui Liu +2 more
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Nickel complexes for catalytic C–H bond functionalization
Dalton Transactions, 2015A search for fundamental understanding of how Ni complexes can be designed to undergo challenging C–H activation reactions provides an entry into unprecedented C–H functionalization reactions.
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Asymmetric Functionalization of C–H Bonds
2015Asymmetric C-H direct functionalization reactions are one of the most active and fascinating areas of research in organic chemistry due to their significance in the construction of molecular complexity without pre-activation, and the step economy and atom economy features in potential synthetic application.
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Selective Functionalization of C–H Bonds
2017Jianhui Huang and Kang Zhao of Tianjin University devised (Chem. Commun. 2013, 49, 1211) a protocol for the oxidation of a terminal alkene 1 to the valuable four-carbon synthon 2. M. Christina White of the University of Illinois effected (J. Am. Chem. Soc. 2013, 135, 7831) the oxidation of the terminal alkene 3 to the enone 4.
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