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Selectivity enhancement in functionalization of C–H bonds: A review

Organic & Biomolecular Chemistry, 2010
The selectivity is an extremely important characteristic of a chemical reaction. This review deals mainly with supramolecular and nano-chemical approaches to the problem of selectivity enhancement in various functionalizations of C-H compounds. Enzyme mimics is a very fruitful method to achieve the predominant formation of desirable products and ...
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Precise Functionalization of Remote C-H Bonds

Chemical Research in Chinese Universities, 2020
Remote C-H bond functionalization of arenes with precise control is a recognized extraordinary challenge in organic synthesis. Recently, Yu and Houk et al. developed an elegant strategy to distinguish and functionalize remote Csp2-H bonds of (hetero)arenes within one-bond distance by the interplay of a remote directing template and a transient ...
Zeshui Liu   +2 more
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Functionalization and Homologation of C-H Bonds

2013
Justin Du Bois of Stanford University developed (J. Am. Chem. Soc. 2010, 132, 10202) a Ru catalyst for the stereoretentive hydroxylation of 1 to 2. John T. Groves of Princeton University effected (J. Am. Chem. Soc. 2010, 132, 12847) equatorial chlorination of the test substrate 3. Kenneth M. Nicholas of the University of Oklahoma found (J. Org.
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Metal-catalyzed C–H bond functionalization of phenol derivatives

, 2020
Phenols and phenol derivatives constitute important starting materials, synthetic intermediates, and functional moieties of a broad range of chemicals and materials. They represent large production products of benzene and benzene derivative oxidation and
Hamad H. Al Mamari   +2 more
semanticscholar   +1 more source

Selective Functionalization of C–H Bonds

2017
Jianhui Huang and Kang Zhao of Tianjin University devised (Chem. Commun. 2013, 49, 1211) a protocol for the oxidation of a terminal alkene 1 to the valuable four-carbon synthon 2. M. Christina White of the University of Illinois effected (J. Am. Chem. Soc. 2013, 135, 7831) the oxidation of the terminal alkene 3 to the enone 4.
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Recent advances and perspectives on the synthesis and C–H bond functionalization of quinoxalin-2(1H)-one

, 2020
Over the past few decades, quinoxalin-2(1H)-one derivatives are serving as active components in diverse families of drugs such as antimicrobial, anticancer, antithrombotic agents and protein kinase inhibitor.
P. Ghosh, S. Das
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Activation and Functionalization of C—H Bonds

2004
Activation and Functionalization of C-H Bonds explores recent developments in the reaction chemistry of solution-phase transition-metal based systems with simple hydrocarbons and with more complex organic molecules. More than 20 internationally leading research groups contributed to this volume, and their chapters cover such topics as fundamental ...
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Recent advances in alkoxy radical-promoted C-C and C-H bond functionalization starting from free alcohols.

Chemical Communications, 2019
Direct functionalization of inert C(sp3)-C(sp3) and C(sp3)-H bonds represents one of the most valuable synthetic tactics, yet large obstacles remain in terms of reactivity and selectivity.
Xin-Xin Wu, Chen Zhu
semanticscholar   +1 more source

Asymmetric Functionalization of C–H Bonds

2015
Asymmetric C-H direct functionalization reactions are one of the most active and fascinating areas of research in organic chemistry due to their significance in the construction of molecular complexity without pre-activation, and the step economy and atom economy features in potential synthetic application.
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Cobalt-Catalyzed C-H Bond Functionalization

The ultimate goal of organic synthetic chemistry is to design and synthesize more complex structures from simple molecules. Classic organic synthesis often relies on the manipulations of functional groups. In organic chemistry, the term 'C-H bond functionalization' is used to describe a chemical reaction, in which a C-H bond of a substrate is cleaved ...
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