Results 181 to 190 of about 195,376 (282)

The Roles of c-Jun N-Terminal Kinase (JNK) in Infectious Diseases. [PDF]

open access: yesInt J Mol Sci, 2021
Chen J   +6 more
europepmc   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet   +8 more
wiley   +1 more source

Correction: Inhibition of c-Jun N-Terminal kinase attenuates low shear stress-induced atherogenesis in apolipoprotein E-deficient mice. [PDF]

open access: yesMol Med, 2022
Wang J   +10 more
europepmc   +1 more source

MITOGEN‐ACTIVATED PROTEIN KINASE9 fine‐tunes hypoxia signaling by phosphorylating ERF‐VII transcription factors in Arabidopsis

open access: yesNew Phytologist, EarlyView.
Summary In plants, hypoxia sensing is controlled by the stabilization of group VII ethylene response factors (ERF‐VIIs), which are post‐translationally activated by the mitogen‐activated protein kinases (MAPKs) MPK3 and MPK6. However, how plants fine‐tune the MPK3/MPK6‐mediated phosphorylation of ERF‐VIIs to maintain cellular homeostasis remains ...
De‐Mian Zhou   +9 more
wiley   +1 more source

Lily Transcription Factors LlPLATZ1 and LlMYB4 Orchestrate the Homeostasis of Heat Stress Responses via Antagonistic Regulation of LlHSF24

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Heat stress significantly damages crop yield and quality. PLATZ (PLANT A/T‐RICH SEQUENCE‐AND ZINC‐BINDING PROTEIN) transcription factors play pivotal roles in plant growth, development, and environmental stress responses. While the functions of PLATZ members in response to drought and salt stress are well characterised, their roles in heat ...
Xue Gong   +7 more
wiley   +1 more source

Safety, Pharmacokinetics, and Pharmacodynamics of CC-90001 (BMS-986360), a c-Jun N-terminal Kinase Inhibitor, in Phase 1 Studies in Healthy Participants. [PDF]

open access: yesClin Pharmacol Drug Dev, 2022
Ye Y   +11 more
europepmc   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

open access: yesPhotochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal   +3 more
wiley   +1 more source

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