Results 201 to 210 of about 195,376 (282)

Astragaloside IV ameliorates insulin induced insulin resistance in HepG2 cells through reactive oxygen species mediated c-Jun N-terminal kinase pathway. [PDF]

J Tradit Chin Med, 2023
Xiaomei YE, Xiaowei X, Kangrui Y, Dongming W, Dudu WU, Zhi C, Zhiqiang YU.   +6 more
europepmc   +1 more source

Cardioprotection via vagus nerve stimulation preconditioning: Reducing ischaemia–reperfusion injury and arrhythmic risk

Experimental Physiology, EarlyView.
Abstract Acute myocardial infarction is a leading cause of morbidity and mortality, with ischaemia–reperfusion (I/R) injury exacerbating myocardial damage. Vagus nerve stimulation (VNS) has been reported to exert cardioprotective effects, but its efficacy in preconditioning against I/R injury requires further investigation.
Feng Hu, Yali Wang, Guangyu Li, Guangyu Wang, Qi Zhuang, Jinyao Jiang, Danfeng Hu, Lihui Zheng, Yan Yao, Minhua Zang, Jun Pu   +10 more
wiley   +1 more source

"A Mighty Flame Can Follow a Tiny Spark": Is This the Case of c-Jun N-Terminal Kinase 1 Inhibitors in Idiopathic Pulmonary Fibrosis? [PDF]

Am J Respir Crit Care Med
Luppi F, Ferrara G.
europepmc   +1 more source

Reduction of sporadic and neurofibromatosis type 2-associated vestibular schwannoma growth in vitro and in vivo after treatment with the c-Jun N-terminal kinase inhibitor AS602801. [PDF]

J Neurosurg, 2023
Dougherty MC, Shibata SB, Clark JJ, Canady FJ, Yates CW, Hansen MR.   +5 more
europepmc   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Editorial expression of concern: Withanolide D induces apoptosis in leukemia by targeting the activation of neutral sphingomyelinase-ceramide cascade mediated by synergistic activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase. [PDF]

Mol Cancer
Mondal S, Mandal C, Sangwan R, Chandra S, Mandal C.   +4 more
europepmc   +1 more source

Retracted: Activation of CD137 Signaling Enhances Vascular Calcification through c-Jun N-Terminal Kinase-Dependent Disruption of Autophagic Flux. [PDF]

Mediators Inflamm, 2022
Inflammation MO.
europepmc   +1 more source

Impact of combined ginsenoside‐MC1 and irisin on mitochondrial apoptosis in diabetic rats with hepatic reperfusion injury: Role of AMPK/JNK signalling

Experimental Physiology, EarlyView.
Abstract Hepatic ischaemia–reperfusion (IR) injury is a serious clinical issue, especially in patients with type 2 diabetes mellitus (T2DM). As mitochondria play a critical role in the regulation of IR‐induced liver damage, mitochondria‐targeted treatment is of the utmost significance for improving outcomes.
Jie Lin, Lei Han, Zhigang Ma, Bo Yuan, Yabin Yu   +4 more
wiley   +1 more source

Probenecid Inhibits Extracellular Signal-Regulated Kinase and c-Jun N-Terminal Kinase Mitogen-Activated Protein Kinase Pathways in Regulating Respiratory Syncytial Virus Response. [PDF]

Int J Mol Sci
Jones LP, Bergeron HC, Martin DE, Murray J, Sancilio FD, Tripp RA.   +5 more
europepmc   +1 more source

Induction of Antimicrobial Protein S100A15 Expression by Oral Microbial Pathogens Is Toll-like Receptors-Dependent Activation of c-Jun-N-Terminal Kinase (JNK), p38, and NF-κB Pathways. [PDF]

Int J Mol Sci, 2023
Selimovic D, Kharouf N, Carrouel F, Hassan SY, Flanagan TW, Hassan SL, Megahed M, Haikel Y, Santourlidis S, Hassan M.   +9 more
europepmc   +1 more source