Tumor Biology, 2017 Periostin (POSTN) is an extracellular matrix protein which is overexpressed in a variety of cancers and has been related to tumorigenesis of renal cell carcinoma.
Sun Chuanyu +4 more
doaj +1 more source
Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]
, 2015 A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding +8 more
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Journal of Pharmacological Sciences, 2009 The organotin trimethyltin (TMT) is known to cause neuronal degeneration in the central nervous system. A systemic injection of TMT produced neuronal damage in the cerebral frontal cortex of mice.
Makoto Shuto +7 more
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Toll pathway modulates TNF-induced JNK-dependent cell death in Drosophila [PDF]
Open Biology, 2015 Signalling networks that control the life or death of a cell are of central interest in modern biology. While the defined roles of the c-Jun N-terminal kinase (JNK) pathway in regulating cell death have been well-established, additional factors that ...
Chenxi Wu +7 more
doaj +1 more source
Spinal release of tumour necrosis factor activates c-Jun N-terminal kinase and mediates inflammation-induced hypersensitivity. [PDF]
, 2014 BackgroundMounting evidence points to individual contributions of tumour necrosis factor-alpha (TNF) and the c-Jun N-terminal kinase (JNK) pathway to the induction and maintenance of various pain states.
Abdelmoaty, S +8 more
core +2 more sources
KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS [PDF]
, 2017 Neurons in the adult mammalian CNS decrease in intrinsic axon growth capacity during development in concert with changes in Krüppel-like transcription factors (KLFs). KLFs regulate axon growth in CNS neurons including retinal ganglion cells (RGCs). Here,
Apara, Akintomide +16 more
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Anticancer Activities of Meroterpenoids Isolated from the Brown Alga Cystoseira usneoides against the Human Colon Cancer Cells HT-29 [PDF]
, 2020 Colorectal cancer (CRC) is one of the most common types of cancers and a leading cause of cancer death worldwide. The current treatment for CRC mainly involves surgery, radiotherapy, and chemotherapy. However, due to the side effects and the emergence of
Calderón-Montaño, Jose M. +4 more
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Inhibition of c-Jun N-terminal kinase (JNK) suppresses porcine oocyte ageing in vitro
Czech Journal of Animal Science, 2013 Oocyte ageing is a complex of processes that occur when matured in vitro oocytes are, after reaching the metaphase II stage, exposed to further in vitro culture.
M. Sedmíková +7 more
doaj +1 more source
c-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo. [PDF]
, 2014 Altered synaptic function is considered one of the first features of Alzheimer disease (AD). Currently, no treatment is available to prevent the dysfunction of excitatory synapses in AD.
Abaza, A. +8 more
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Anti-inflammatory effect of supercritical extract and its constituents from Ishige okamurae [PDF]
, 2016 The anti-inflammatory properties of the supercritical fluid extract of Ishige okamurae (SFEIO) on lipopolysaccharide (LPS)-stimulated murine RAW 264.7 macrophages.
Ahn, Ginnae +12 more
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