Results 21 to 30 of about 81,063 (242)

Differentiation of IL-17-Producing Invariant Natural Killer T Cells Requires Expression of the Transcription Factor c-Maf

open access: yesFrontiers in Immunology, 2017
c-Maf belongs to the large Maf family of transcription factors and plays a key role in the regulation of cytokine production and differentiation of TH2, TH17, TFH, and Tr1 cells.
Jhang-Sian Yu   +5 more
doaj   +1 more source

The ubiquitin-conjugating enzyme UBE2O modulates c-Maf stability and induces myeloma cell apoptosis

open access: yesJournal of Hematology & Oncology, 2017
Background UBE2O is proposed as a ubiquitin-conjugating enzyme, but its function was largely unknown. Methods Mass spectrometry was applied to identify c-Maf ubiquitination-associated proteins.
Yujia Xu   +10 more
doaj   +1 more source

Multiple Environmental Signaling Pathways Control the Differentiation of RORγt-Expressing Regulatory T Cells

open access: yesFrontiers in Immunology, 2020
RORγt-expressing Tregs form a specialized subset of intestinal CD4+ Foxp3+ cells which is essential to maintain gut homeostasis and tolerance to commensal microbiota.
Hind Hussein   +9 more
doaj   +1 more source

Carbon Isotopic Signature and Organic Matter Composition of Cenomanian High-Latitude Paleosols of Southern Patagonia

open access: yesGeosciences, 2021
The Cenomanian Mata Amarilla Formation (MAF) in southern Patagonia (~55° S paleolatitude, Austral-Magallanes Basin, Argentina) is composed mainly of stacked fluvial deposits with intercalated paleosols, which document Cenomanian environments at high ...
Augusto Nicolás Varela   +5 more
doaj   +1 more source

The transcription factor c-Maf in sensory neuron development [PDF]

open access: yesTranscription, 2012
The proto-oncogene c-Maf has been shown to be an important transcriptional regulator in the differentiation of a number of cellular contexts, like the eye and hematopoietic system. Here we discuss the recent progress made in understanding c-Maf function in the nervous system.
Hagen, Wende   +2 more
openaire   +2 more sources

c-Maf and you won’t see fat [PDF]

open access: yesJournal of Clinical Investigation, 2010
Osteoporosis is a common, age-related bone disease that results from an imbalance between the processes of bone formation and bone resorption, resulting in reduced bone mass and increased risk of fracture. Mesenchymal stem cells have the capacity to differentiate into osteoblastic and adipogenic lineages; recent research suggests that the switch ...
openaire   +2 more sources

Evolution of microstructure and mechanical properties of Ti-based metal-matrix composites during hot deformation [PDF]

open access: yesMATEC Web of Conferences, 2020
Two Ti-based composites, viz. Ti/TiB and Ti-15Mo/TiB were produced by spark plasma sintering using a Ti-10wt.%TiB2 powder mixture at 1000°C or Ti-14.25(wt.)%Mo-5(wt.)%TiB2 powder mixture at 1400°C, respectively.
Zherebtsov S.   +5 more
doaj   +1 more source

TACI expression is associated with a mature bone marrow plasma cell signature and C-MAF overexpression in human myeloma cell lines

open access: yesHaematologica, 2007
Background and Objectives BAFF and APRIL stimulate the growth of multiple myeloma (MM) cells. BAFF and APRIL share two receptors – TACI and BCMA – and BAFF binds to a third receptor, BAFF-R.
Jérôme Moreaux   +10 more
doaj   +1 more source

Clinical implications of c-maf expression in plasma cells from patients with multiple myeloma

open access: yesExperimental Hematology & Oncology, 2017
Background Multiple myeloma (MM) is a type of hematological malignancy with significant heterogeneity in clinical features and prognosis. Cytogenetic abnormalities are the major factors affecting patient outcomes.
GuoQing Wei   +13 more
doaj   +1 more source

Regulation of c-maf gene expression by Pax6 in cultured cells [PDF]

open access: yesNucleic Acids Research, 2001
c-Maf is a bZip transcription factor expressed in developmental and cellular differentiation processes. Recently, a c-maf knockout mouse model, showing abnormal lens development, has been reported. In order to study the regulation mechanisms of c-maf gene expression during the differentiation process we have cloned and functionally characterized the ...
M, Sakai   +5 more
openaire   +2 more sources

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