Results 181 to 190 of about 279,069 (213)

NIBAN2 Stimulates Glioma Growth by Regulating the JAK2/STAT3/c-Myc Pathway. [PDF]

Cancer Med
Chen ZM, Mou L, Pan YH, Feng C, Liu J, Zhang JJ, Yan CX.   +6 more
europepmc   +1 more source

SIZ1‐Mediated SUMOylation of LBD29 Recruits ARF7 to Fine‐Tune Auxin Signaling in Lateral Root Development

Advanced Science, EarlyView.
Our findings establish SUMOylation as a key post‐translational control layer in auxin signaling. We show that SIZ1‐mediated SUMOylation of LBD29 promotes its association with ARF7, stabilizing a transcriptional hub that governs lateral root development.
Jiaxuan Sui, Qianlan Yin, Yiying Chen, Liping Zhang, Xiuyuan Yu, Qianqian Yu, Zhaojun Ding, Xiangpei Kong   +7 more
wiley   +1 more source

c-Myc Inhibits Macrophage Antimycobacterial Response in Mycobacterium tuberculosis Infection. [PDF]

J Infect Dis
Sarti E, Dollé C, Wolfensberger R, Kusejko K, Russenberger D, Bredl S, Speck RF, Greter M, Rueschoff JH, Boeck L, Mai D, Jahn AN, Gold ES, Liu D, Diercks AH, Sander P, Olson GS, Nemeth J.   +17 more
europepmc   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Triglyceride lipase PNPLA2-independent suppression of c-MYC signaling by the metabolic coactivator ABHD5 in prostate cancer. [PDF]

J Biol Chem
Lotvola A, Chen G, Zhou G, Granneman JG, Wang J.   +4 more
europepmc   +1 more source

Programmable Nanobody‐Targeting Chimeras Enable Intracellular Viral Protein Degradation

Advanced Science, EarlyView.
Nab‐TAC enables targeted degradation of HBV surface antigen (HBsAg) in vivo. By fusing nanobody‐based recognition domains with programmable proteasome‐recruiting degradation signals, Nab‐TAC reduces HBsAg levels in a hydrodynamic HBV mouse model. ABSTRACT Chronic hepatitis B virus (HBV) infection remains a major global health challenge, largely because
Max Yu‐Chen Pan, Ting‐Hui Lee, Tzu‐Ning Peng, Eva Yi‐Hsuan Wu, Yu‐Ting Chiu, Chih‐Chien Chiu, Hong Vinh Nguyen, Yuan‐Shao Pao, Ming‐Hong Chao, Richard Kuan‐Lin Lee, Han‐Chung Wu, Lily Hui‐Ching Wang   +11 more
wiley   +1 more source

KAT3B acts as an oncogene in PCa by mediating the succinylation of c-Myc and promoting its stability. [PDF]

World J Surg Oncol
Nie W, Cha S, Fu Q.
europepmc   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

c-Myc transactivates CFL1 to induce senescence-like phenotype and potentiate the bystander effects for the migration and proliferation in lung cancer cells. [PDF]

Cell Death Discov
Chou YT, Leu JD, Yang WY, Li CH, Lin MY, Kao CW, Chang YC, Hsiao M, Lee YJ.   +8 more
europepmc   +1 more source

Epithelial AhR Suppresses Allergen-Induced Oxidative Stress and Senescence via c-Myc Regulation. [PDF]

Antioxidants (Basel)
Chen Z, Gu W, Wan R, Zeng Y, Xiang X, Ouyang R, Gao P.   +6 more
europepmc   +1 more source