Results 101 to 110 of about 467,569 (310)

The role of a disulfide bridge in the stability and folding kinetics of Arabidopsis thaliana cytochrome c6A [PDF]

, 2011
Cytochrome c 6A is a eukaryotic member of the Class I cytochrome c family possessing a high structural homology with photosynthetic cytochrome c 6 from cyanobacteria, but structurally and functionally distinct through the presence of a disulfide bond and
Arslan, Babul, Barker, Bartalesi, Beasty, Bertini, Betz, Bialek, Borgia, Brems, Carter, Chen, Chida, Christopher J. Howe, Cohen, Colon, Colon, Derek S. Bendall, Ellman, Elove, Feige, Gianni, Guidry, Gupta, Hogg, Howe, Jody M. Mason, Jonathan A.R. Worrall, Lange, Lange, Marcaida, Mason, Mason, Merchant, Mines, Molina-Heredia, Moore, Myers, Ogawa, Pace, Pace, Parrini, Pascher, Ptitsyn, Roder, Russell, Russell, Santoro, Satoh, Sauder, Schlarb-Ridley, Schmidt, Sosnick, Tezcan, Travaglini-Allocatelli, Travaglini-Allocatelli, Travaglini-Allocatelli, Ullah, Ullah, Wastl, Wastl, Wastl, Williams, Worrall, Worrall   +64 more
core   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, EarlyView.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space [PDF]

, 1992
Cytochrome b2 reaches the intermembrane space of mitochondria by transport into the matrix followed by export across the inner membrane. While in the matrix, the protein interacts with hsp60, which arrests its folding prior to export.
Guiard, Bernard, Hartl, Franz-Ulrich, Horwich, Arthur, Koll, Hans, Neupert, Walter, Ostermann, Joachim, Rassow, Joachim   +6 more
core   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB [PDF]

, 2018
With the emergence of multidrug-resistant strains of Mycobacterium tuberculosis there is a pressing need for new oral drugs with novel mechanisms of action.
Cleghorn, Laura, Davis, Susan, Epemolu, Rafiu, Ferguson, Liam, Green, Simon, Guijarro, Laura, Hipskind, Phil, Huggett, Margaret, Korkegian, Aaron, Kumar, Anuradha, Lopez Moure, Abraham, Masquelin, Thierry, Odingo, Joshua, Parish, Tanya, Ray, Peter, Read, Kevin, Riley, Jennifer, Rullas, Joaquin, Scullion, Stanley, Shishikura, Yoko, Smith, Alasdair, Turner, Penelope, Wescott, Heather, Wilson, Caroline, Wyatt, Paul, Zuccotto, Fabio   +25 more
core   +4 more sources

Engineered Heparinized GQDS/HPEI–Polyamide Membrane for Bilirubin Removal via One Step Anti Coagulation

Advanced Materials Interfaces, EarlyView.
A multifunctional heparinized polyamide membrane embedded with graphene quantum dots (GQDs) and hyperbranched polyethyleneimine (HPEI) is engineered for efficient bilirubin removal via a one‐step anticoagulation–adsorption process. The membrane demonstrates enhanced hemocompatibility, prolonged clotting times, and high bilirubin adsorption capacity ...
Abdur Rehman Mushtaq Ahmad, Maria Wasim, Aneela Sabir, Muhammad Shafiq, Syed Abdul Basit Shah, Maoz Maoz, Vanni Lughi   +6 more
wiley   +1 more source

C-type cytochrome-initiated reduction of bacterial lytic polysaccharide monooxygenases. [PDF]

Biochem J, 2021
Branch J, Rajagopal BS, Paradisi A, Yates N, Lindley PJ, Smith J, Hollingsworth K, Turnbull WB, Henrissat B, Parkin A, Berry A, Hemsworth GR.   +11 more
europepmc   +1 more source

Mutational Analysis of the QRRQ Motif in the Yeast Hig1 Type 2 Protein Rcf1 Reveals a Regulatory Role for the Cytochrome \u3cem\u3ec\u3c/em\u3e Oxidase Complex [PDF]

, 2017
The yeast Rcf1 protein is a member of the conserved family of proteins termed the hypoxia-induced gene (domain) 1 (Hig1 or HIGD1) family. Rcf1 interacts with components of the mitochondrial oxidative phosphorylation system, in particular the cytochrome ...
Garlich, Joshua, Strecker, Valentina, Stuart, Rosemary A., Wittig, Ilka   +3 more
core   +1 more source

Molecular Basis and Consequences of the Cytochrome c-tRNA Interaction. [PDF]

, 2016
The intrinsic apoptosis pathway occurs through the release of mitochondrial cytochrome c to the cytosol, where it promotes activation of the caspase family of proteases.
Christian, Thomas, Hou, Ya-Ming, Liu, Cuiping, Stonestrom, Aaron J, Takase, Ryuichi, Yang, Xiaolu, Yong, Jeongsik   +6 more
core   +2 more sources

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

Advanced Materials Interfaces, EarlyView.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido, Aída Jimena Velarde‐Salcedo, Alejandro López‐Amador, Noé Arjona, Citlali Uitz Toalá, Carmen Gonzalez, Beatriz Liliana España‐Sánchez   +6 more
wiley   +1 more source