Results 11 to 20 of about 292,332 (117)

Radical Mediated Rapid In Vitro Formation of c-Type Cytochrome [PDF]

Biomolecules, 2022
A cytochrome c552 mutant from Thermus thermophilus HB8 (rC552 C14A) was reported, where the polypeptide with replaced Cys14 by alanine, overexpressed in the cytosol of E. coli.
Sheikh Muhammad Ibrahim, Sami Ben Aoun, Hiroshi Nakajima, Fethi Kooli, Yoshihito Watanabe   +4 more
doaj   +2 more sources

c-Type Cytochrome Assembly Is a Key Target of Copper Toxicity within the Bacterial Periplasm [PDF]

mBio, 2015
In the absence of a tight control of copper entrance into cells, bacteria have evolved different systems to control copper concentration within the cytoplasm and the periplasm.
Anne Durand, Asma Azzouzi, Marie-Line Bourbon, Anne-Soisig Steunou, Sylviane Liotenberg, Akinori Maeshima, Chantal Astier, Manuela Argentini, Shingo Saito, Soufian Ouchane   +9 more
doaj   +2 more sources

Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease. [PDF]

PLoS ONE, 2016
Niemann-Pick type C (NPC) disease is a neurodegenerative lysosomal storage disease caused by mutations in either the NPC1 or NPC2 gene. NPC is characterised by storage of multiple lipids in the late endosomal/lysosomal compartment, resulting in cellular ...
Elena-Raluca Nicoli, Nada Al Eisa, Celine V M Cluzeau, Christopher A Wassif, James Gray, Kathryn R Burkert, David A Smith, Lauren Morris, Stephanie M Cologna, Cody J Peer, Tristan M Sissung, Constantin-Daniel Uscatu, William D Figg, William J Pavan, Charles H Vite, Forbes D Porter, Frances M Platt   +16 more
doaj   +1 more source

Comparative insights into genome signatures of ferric iron oxide- and anode-stimulated Desulfuromonas spp. strains

BMC Genomics, 2021
Background Halotolerant Fe (III) oxide reducers affiliated in the family Desulfuromonadaceae are ubiquitous and drive the carbon, nitrogen, sulfur and metal cycles in marine subsurface sediment.
Yong Guo, Tomo Aoyagi, Tomoyuki Hori
doaj   +1 more source

New insight into the mechanism of mitochondrial cytochrome c function. [PDF]

PLoS ONE, 2017
We investigate functional role of the P76GTKMIFA83 fragment of the primary structure of cytochrome c. Based on the data obtained by the analysis of informational structure (ANIS), we propose a model of functioning of cytochrome c. According to this model,
Rita V Chertkova, Nadezda A Brazhe, Tatiana V Bryantseva, Alexey N Nekrasov, Dmitry A Dolgikh, Alexander I Yusipovich, Olga Sosnovtseva, Georgy V Maksimov, Andrei B Rubin, Mikhail P Kirpichnikov   +9 more
doaj   +1 more source

A biochemical approach to study the role of the terminal oxidases in aerobic respiration in Shewanella oneidensis MR-1. [PDF]

PLoS ONE, 2014
The genome of the facultative anaerobic γ-proteobacterium Shewanella oneidensis MR-1 encodes for three terminal oxidases: a bd-type quinol oxidase and two heme-copper oxidases, a A-type cytochrome c oxidase and a cbb 3-type oxidase.
Sébastien Le Laz, Arlette Kpebe, Marielle Bauzan, Sabrina Lignon, Marc Rousset, Myriam Brugna   +5 more
doaj   +1 more source

Multi-heme cytochrome-mediated extracellular electron transfer by the anaerobic methanotroph ‘Candidatus Methanoperedens nitroreducens’

Nature Communications, 2023
Anaerobic methanotrophic archaea (ANME) carry out anaerobic oxidation of methane, thus playing a crucial role in the methane cycle. Previous genomic evidence indicates that multi-heme c-type cytochromes (MHCs) may facilitate the extracellular electron ...
Xueqin Zhang, Georgina H. Joyce, Andy O. Leu, Jing Zhao, Hesamoddin Rabiee, Bernardino Virdis, Gene W. Tyson, Zhiguo Yuan, Simon J. McIlroy, Shihu Hu   +9 more
doaj   +1 more source

Unique organizational and functional features of the cytochrome c maturation system in Shewanella oneidensis. [PDF]

PLoS ONE, 2013
Shewanella are renowned for their ability to respire on a wide range of electron acceptors, which has been partially accredited to the presence of a large number of the c-type cytochromes. In the model species S. oneidensis MR-1, at least 41 genes encode
Miao Jin, Yaoming Jiang, Linlin Sun, Jianhua Yin, Huihui Fu, Genfu Wu, Haichun Gao   +6 more
doaj   +1 more source

Multiple Mutations in the Non-Ordered Red Ω-Loop Enhance the Membrane-Permeabilizing and Peroxidase-like Activity of Cytochrome c

Biomolecules, 2022
A key event in the cytochrome c-dependent apoptotic pathway is the permeabilization of the outer mitochondrial membrane, resulting in the release of various apoptogenic factors, including cytochrome c, into the cytosol.
Rita V. Chertkova, Alexander M. Firsov, Nadezda A. Brazhe, Evelina I. Nikelshparg, Zhanna V. Bochkova, Tatyana V. Bryantseva, Marina A. Semenova, Adil A. Baizhumanov, Elena A. Kotova, Mikhail P. Kirpichnikov, Georgy V. Maksimov, Yuriy N. Antonenko, Dmitry A. Dolgikh   +12 more
doaj   +1 more source

PINK1 mutants associated with recessive Parkinson’s disease are defective in inhibiting mitochondrial release of cytochrome c

Neurobiology of Disease, 2007
Mutations in PTEN-induced kinase 1 (PINK1) gene cause recessive familial type 6 of Parkinson’s disease (PARK6). We investigated molecular mechanisms underlying PINK1 neuroprotective function and PARK6 mutation-induced loss of PINK1 function ...
Hung-Li Wang, An-Hsun Chou, Tu-Hsueh Yeh, Allen H. Li, Ying-Ling Chen, Yu-Li Kuo, Shu-Ru Tsai, Szu-Tzu Yu   +7 more
doaj   +1 more source