Results 111 to 120 of about 28,074,578 (229)

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Research progress on the pattern recognition receptors involved in porcine reproductive and respiratory syndrome virus infection

Frontiers in Cellular and Infection Microbiology
Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically devastating infectious diseases of pigs globally. The pathogen, porcine reproductive and respiratory syndrome virus (PRRSV), is an enveloped positive-stranded RNA virus,
Yulin Xu, Yulin Xu, Luogang Ding, Luogang Ding, Yuyu Zhang, Yuyu Zhang, Sufang Ren, Sufang Ren, Jianda Li, Jianda Li, Fei Liu, Fei Liu, Wenbo Sun, Wenbo Sun, Zhi Chen, Zhi Chen, Jiang Yu, Jiang Yu, Jiaqiang Wu, Jiaqiang Wu   +19 more
doaj   +1 more source

VML, uma lectina com afinidade por galactose isolada das sementes de vatairea macrocarpa, pode induzir resposta neurotóxicas [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Bioquímica, Florianópolis, 2013Lectinas são proteínas que se ligam a carboidratos presentes em glicoconjugados podendo regular ...
Gonçalves, Filipe Marques
core  

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Ly49 receptors: Innate and adaptive immune paradigms

Frontiers in Immunology, 2014
The Ly49 receptors are type II C-type lectin-like membrane glycoproteins encoded by a family of highly polymorphic and polygenic genes within the mouse natural killer gene complex (NKC). This gene family is designated Klra, and includes genes that encode
Mir Munir A Rahim, Megan M Tu, Ahmad Bakur Mahmoud, Andrew eWight, Elias eAbou-Samra, Patricia D. A. Lima, Andrew P Makrigiannis   +6 more
doaj   +1 more source

Ratiometric pH‐Responsive and Biomimetic Microparticles for Quantitative Monitoring of Phagosomal Acidification

Chemistry – A European Journal, EarlyView.
A series of hydrosoluble BODIPY pH probes allows building biomimetic pH sensors based on micrometric oil‐in‐water droplets. The ratiometric fluorescence output offers quantitative information on the evolution of pH during phagosome maturation. ABSTRACT We present a modular biomimetic fluorescent sensing platform designed to precisely interrogate the ...
Sophie Michelis, Héloïse Uhl, Florence Niedergang, Jacques Fattaccioli, Blaise Dumat, Jean‐Maurice Mallet   +5 more
wiley   +1 more source

Interplay between bacteria and pulmonary immune system in respiratory infections

hLife
The local immune system of the lungs is essential for the defense against pathogens, and respiratory bacterial infections remain a major cause of mortality in patients with lower respiratory tract diseases.
Jiaqi Li, Letong Yang, Xiwen Qin, Min Zhao, Shuo Wang   +4 more
doaj   +1 more source

Innate Immunity against Cryptococcus, from Recognition to Elimination

Journal of Fungi, 2018
Cryptococcus species, the etiological agents of cryptococcosis, are encapsulated fungal yeasts that predominantly cause disease in immunocompromised individuals, and are responsible for 15% of AIDS-related deaths worldwide.
Althea Campuzano, Floyd L. Wormley
doaj   +1 more source

Oogenesis and germinal bed morphology of the brown anole (A. sagrei)

Developmental Dynamics, EarlyView.
Abstract Background The brown anole is a model species of the genus Anolis, a squamate (encompassing lizards and snakes) group widely studied in evolutionary, behavioral, and developmental biology. Full genome annotation, the establishment of gene editing techniques, and comprehensive description of reproductive tract morphology and embryogenesis in ...
Bonnie K. Kircher, Antonia Weberling, Erin J. Vance, Natalia A. Shylo, Katherine Starr, Zoe B. Griffin, Hannah Wilson, Melainia McClain, Florian Hollfelder, Suzannah A. Williams, Thomas J. Sanger, Richard R. Behringer, Paul A. Trainor   +12 more
wiley   +1 more source

Innate Immune Effectors in Mycobacterial Infection

Clinical and Developmental Immunology, 2011
Tuberculosis, which is caused by infection with Mycobacterium tuberculosis (Mtb), remains one of the major bacterial infections worldwide. Host defense against Mtb is mediated by a combination of innate and adaptive immune responses. In the last 15 years,
Hiroyuki Saiga, Yosuke Shimada, Kiyoshi Takeda   +2 more
doaj   +1 more source