Results 191 to 200 of about 69,600 (248)

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

An atypical venus fly trap domain receptor regulates motility and phagocytosis in the protozoan parasite Entamoeba histolytica. [PDF]

PLoS Pathog
Nugraha RYB, Jeelani G, Santos HJ, Nozaki T.   +3 more
europepmc   +1 more source

Gait analysis for functional evaluation in a surgical hindlimb suspension model of muscle atrophy

The Journal of Physiology, EarlyView.
Abstract figure legend Gait analysis reveals neuromuscular dysfunction following hindlimb suspension and partial recovery after reloading. Schematic overview of the experimental design and principal findings. Mice underwent 14 days of hindlimb suspension (HLS), resulting in muscle atrophy marked by reduced fiber size, satellite cell loss, and decreased
Yanping Xu, Zhentao Zhang, Peng Chen, Natalie Kellon, Ashley He, Usman Alizai, Sunjoon Lee, Keerthika Sathish, Zhiyu Yan, Xinyu Zhou, Laura Kutz, Diamantis I. Tsilimigras, Timothy M. Pawlik, Hua Zhu   +13 more
wiley   +1 more source

Emergence, function, and therapeutic strategies to target the PD-1/PD-L1 immune checkpoint during pathogenic fungal infections. [PDF]

Virulence
Zheng X, He X, Song Z, Chen W, Liu F.
europepmc   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

Single-cell transcriptomics of Pacific white shrimp (<i>Litopenaeus vannamei</i>) hepatopancreas reveal immune and metabolic responses to AHPND-causing <i>Vibrio parahaemolyticus</i>. [PDF]

Front Immunol
Aldersey JE, Abernathy JW, Lange MD, García JC, Shoemaker CA, Beck BH.   +5 more
europepmc   +1 more source

Skeletal muscle adaptation to muscle activity and hypoxia: Differential structural and metabolic remodelling

The Journal of Physiology, EarlyView.
Abstract figure legend There has been controversy about the structural (capillary) response of skeletal muscle to altered O2 status, involving decreased supply (hypoxia) or increased demand (activity). Here we demonstrate that seven days of activation of skeletal muscle by indirect electrical stimulation led to significant expansion of the capillary ...
David Hauton, Roger W.P. Kissane, James McCullagh, Stuart Egginton   +3 more
wiley   +1 more source

Autosomal Dominant Erythrocytosis Caused by Non‐Renal Erythropoietin (EPO) Due to EPO c.‐136 G>A Germline Mutation

American Journal of Hematology, Volume 101, Issue 4, Page 784-793, April 2026.
A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova, Dusan Hrckulak, Veronika Zimolova, Felipe R. Lorenzo, Jihyun Song, Katerina Vecerkova, Olga Babosova, Linda Berkova, Vladimir Korinek, Steve Elliott, Josef T. Prchal   +10 more
wiley   +1 more source

Mannose Derivatives as Anti-Infective Agents. [PDF]

Int J Mol Sci
Ribić R.
europepmc   +1 more source

The role of T cells in sepsis of distinct infectious aetiologies

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu, Bijun Zhu, Wanxin Duan, Ruixiang Kang, Xiangdong Wang, Liyang Li   +5 more
wiley   +1 more source