Enhanced Single‐Particle Upconversion Imaging via Energy Migration Boosting
Advanced Science, EarlyView.A core‐shell‐shell Yb3⁺/Er3⁺ UCNP architecture is engineered to balance energy migration and back energy transfer, yielding more than a tenfold enhancement in single‐particle brightness. Leveraging these optimized probes, it achieves long‐term, high‐resolution single‐particle tracking in live neurons, uncovering coordinated transport mechanisms of ...
Yanxin Zhang +7 more
wiley +1 more source
Multi-lectin Affinity Chromatography and Quantitative Proteomic Analysis Reveal Differential Glycoform Levels between Prostate Cancer and Benign Prostatic Hyperplasia Sera. [PDF]
, 2018 Currently prostate-specific antigen is used for prostate cancer (PCa) screening, however it lacks the necessary specificity for differentiating PCa from other diseases of the prostate such as benign prostatic hyperplasia (BPH), presenting a clinical need
Adusumilli, Ravali +6 more
core +2 more sources
MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis
Advanced Science, EarlyView.This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang +18 more
wiley +1 more source
Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex
Advanced Science, EarlyView.The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano +11 more
wiley +1 more source
Characterization of a Novel Member of the Macrophage Mannose Receptor Type C Lectin Family [PDF]
, 1996 Kai Wu, Jean Q. Yuan, Laurence A. Lasky
openalex +1 more source
Measuring cell adhesion forces with the atomic force microscope at the molecular level [PDF]
, 2002 In the past 25 years many techniques have been developed to characterize cell adhesion and to quantify adhesion forces. Atomic force microscopy (AFM) has been used to measure forces in the pico-newton range, an experimental technique known as force ...
Benoit, M., Gaub, H. E.
core +1 more source
Aggregate, EarlyView.To overcome poor molecular recognition in dilute solutions of tetraphenylethylene‐embedded cyclo[6]arenes, three macrocycles with functionalized cavities featuring diazine groups as endo‐binding sites are synthesized. Their recognition affinity continuously improves with increasing hydrogen‐bond acceptance of diazine groups.
Nan Pan +6 more
wiley +1 more source
B cells in the bursa of Fabricius express a novel C-type lectin gene. [PDF]
, 1997 Ryo Goitsuka, C H Chen, M D Cooper
openalex +1 more source
Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts
American Journal of Hematology, EarlyView.ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent +27 more
wiley +1 more source
Cancer Management and Research, 2012 Sergiy V Kushchayev,1 Tejas Sankar,1 Laura L Eggink,4,5 Yevgeniya S Kushchayeva,5 Philip C Wiener,1,5 J Kenneth Hoober,5,6 Jennifer Eschbacher,3 Ruolan Liu,2 Fu-Dong Shi,2 Mohammed G Abdelwahab,4 Adrienne C Scheck,4 Mark C Preul11Neurosurgery Research ...
Kushchayev SV +11 more
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