Results 131 to 140 of about 161,532 (260)

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

B7 Family Molecule VSIG4 Regulates Pulmonary Anti-Influenza Immune Responses via C-Type Lectin Signal Pathway. [PDF]

Vaccines (Basel)
Zhu J, Lu D, Zhang L, He Z, Ma T, Sun Y, Yu W, Yang X, Tu Y, Fang Y, Li D, Zheng R, Li T, Zhao J, Wang H.   +14 more
europepmc   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Non-receptor tyrosine kinase c-Abl downstream of C-type lectin receptors regulates innate antifungal immunity through c-Cbl/MAPK pathway. [PDF]

Infect Immun
Ma S-J, Xie K-F, Duan J-L, Wang X-L, Yang Y-H, Wang Y.   +5 more
europepmc   +1 more source

C-type lectin receptors

Japanese Journal of Thrombosis and Hemostasis, 2015
openaire   +2 more sources

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Phylogenetic and structural insights into the origin of C-type lectin Mincle in vertebrates. [PDF]

Immunogenetics
Ito T, Guenther C, Ishikawa E, Yabuki T, Nagae M, Nakatani Y, Yamasaki S.   +6 more
europepmc   +1 more source

TGFβ‐Mediated Overexpression of Podoplanin Serves as a Potential Diagnostic Biomarker in Acute Promyelocytic Leukemia

Molecular Carcinogenesis, EarlyView.
ABSTRACT Early diagnosis of acute promyelocytic leukemia (APL), driven by PML‐RARA oncoprotein, is vital for survival, as delays can cause fatal coagulopathy without prompt therapeutic intervention of all‐trans retinoic acid and arsenic trioxide. Although APL is diagnosed using microscopy, immunophenotyping, and FISH/PCR for PML‐RARA, morphological ...
Akash Maity, Rohit Kumar, Madhavi Dutta, Ansit Mishra, Jitendra Gawde, Jagruti Patil, Darshana Kadam, Sumeet Mirgh, Anant Gokarn, Hasmukh Jain, Lingaraj Nayak, Bhausaheb Bagal, Sachin Punatar, Manju Sengar, Navin Khattry, P. G. Subramanian, Prashant Tembhare, Syed K. Hasan   +17 more
wiley   +1 more source

Amniotic fluid glycoproteins as potential ligands for macrophage galactose-type C-type lectin and their possible implications for immunoregulation during pregnancy. [PDF]

Sci Rep
Szczykutowicz J, Zimmer M, Orczyk-Pawiłowicz M.   +2 more
europepmc   +1 more source

Nanomedicine Targeting Macrophage Immunometabolism in Atherosclerosis: Mechanisms and Therapeutic Prospects

Organ Medicine, EarlyView.
ABSTRACT Atherosclerosis, a chronic inflammatory–metabolic disorder, remains a leading cause of cardiovascular morbidity worldwide. This review explores the emerging paradigm of nanomedicine‐based targeting of macrophage immunometabolic reprogramming as a potentially transformative strategy for atherosclerosis treatment.
Zhenyu Liu, Wenfan Yang, Na Wang, Ya Wu
wiley   +1 more source