Results 191 to 200 of about 237,325 (347)

Toward a Genetic Signature of Resistance to Activity‐Based Anorexia in Striatal Projecting Cortical Neurons

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Converging evidence from neuroimaging studies and genome‐wide association study (GWAS) suggests the involvement of prefrontal cortex (PFC) and striatum dysfunction in the pathophysiology of anorexia nervosa (AN). However, identifying the causal role of circuit‐specific genes in the development of the AN‐like phenotype remains ...
K. Huang   +7 more
wiley   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely   +14 more
wiley   +1 more source

Early diagnostic value of novel biomarkers for breast cancer therapy‐related cardiac dysfunction

open access: yesESC Heart Failure, EarlyView.
Our meta‐analysis revealed significant post‐treatment increases in GDF‐15, CRP, MPO, and PLGF levels (Gal‐3 unchanged) among breast cancer patients. Only elevated MPO levels were significantly associated with an increased risk of cancer therapy‐related cardiac dysfunction (CTRCD).
Zhengwei Wang   +4 more
wiley   +1 more source

Galectin‐3 and kidney function in type 2 diabetes treated with dapagliflozin: Analysis from DECLARE‐TIMI 58

open access: yesESC Heart Failure, EarlyView.
Abstract Background Galectin‐3 (Gal‐3) is a circulating biomarker of fibrosis, with higher levels being associated with an increased risk of progression of heart failure and kidney disease. Patients with type 2 diabetes mellitus (T2DM) are at increased risk of both.
Paul M. Haller   +12 more
wiley   +1 more source

The transcriptional profile of iron deficiency in patients with heart failure: Heme‐sparing and reduced immune processes

open access: yesEuropean Journal of Heart Failure, EarlyView.
The analysis workflow, findings and potential clinical consequences of iron deficiency in heart failure (HF). From 881 patients with worsening HF, whole blood transcriptome was analysed using the Affymetrix Human Transcriptome Array (HTA) 2.0. Subjects were stratified according to their transferrin saturation (TSAT) levels as iron‐deficient (TSAT <20%)
Niels Grote Beverborg   +17 more
wiley   +1 more source

Marine Algae‐Derived Bioactives: A Sustainable Resource for the Food and Agriculture Industries

open access: yesFood Frontiers, EarlyView.
Algae are widely used in food and agriculture due to their bioactive compounds and are an eco‐friendly natural preservative and low carbon farming method. However, the problems regarding safety and acceptance still remain as tools like nanotechnology make improvements.
Sara Chadorshabi   +3 more
wiley   +1 more source

Emerging Frontiers in Food Allergy Treatment: Progress, Challenges, and Prospects

open access: yesFood Frontiers, EarlyView.
Food allergy is a rising global health concern with limited treatment options beyond allergen avoidance and emergency care. This review explores the evolving therapeutic landscape, highlighting advances in allergen immunotherapy, biologics such as monoclonal antibodies, and emerging vaccine‐based approaches.
Ayesha Zahid   +3 more
wiley   +1 more source

Integrated scFv identification and CAR T cell generation for AML targeting in vivo

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu   +13 more
wiley   +1 more source

Molecular cloning and characterization of a C-type lectin from Ancylostoma ceylanicum: Evidence for a role in hookworm reproductive physiology [PDF]

open access: green, 2006
Allison C. Brown   +7 more
openalex   +1 more source

Promucetin, a new C-type lectin-like protein modulates coagulation by activating platelets via GPIb. [PDF]

open access: yesJ Venom Anim Toxins Incl Trop Dis
Yu XQ, Zhang QY, Zhou ST, Lu QY, Sun QY.
europepmc   +1 more source

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