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C-Type Lectin Family: Overview [PDF]

open access: possible, 2014
Members of the C-type lectin family of glycan-binding receptors in animals contain modular carbohydrate recognition domains (CRDs) that form a subset of a larger structural class of protein modules designated C-type lectin-like domains. Two broad categories of C-type CRDs bind either mannose and related sugars or galactose and related sugars at the Ca ...
Maureen E. Taylor, Kurt Drickamer
openaire   +1 more source

Emerging Groups of C-Type Lectins [PDF]

open access: possible, 2012
Layilin, a ~55-kDa lectin, is a widely expressed integral membrane hyaluronan receptor, originally identified as a binding partner of talin located in membrane ruffles. It is recruited to membrane ruffles in cells induced to migrate in in vitro wounding experiments and in peripheral ruffles in spreading cells.
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A Family of C-Type Lectins in Manduca sexta

2001
Insects have a rapid and effective immune system against microbial infections (Gillespie et al., 1997) that shares common characteristics with the innate immune system of vertebrates. It also consists of humoral and cellular responses. In the cellular responses such as phagocytosis, nodule formation and encapsulation, hemocytes play important roles. In
Xiao-Qiang Yu, Michael R. Kanost
openaire   +3 more sources

Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation

Signal Transduction and Targeted Therapy, 2022
Lin Zhu, Shoudeng Chen, Xiu-Wu Bian
exaly  

Classification of C‐Type Lectins and Recognition of Pathogens

Microbiology and Immunology
ABSTRACTC‐type lectins are calcium‐dependent glycan‐binding proteins that play key roles in the innate immune response by recognizing pathogens. Soluble C‐type lectins agglutinate and neutralize pathogens, activate the complement system, and promote pathogen clearance via opsonization.
openaire   +2 more sources

Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin

Nature Immunology, 2021
Santiago P Méndez-Huergo   +2 more
exaly  

Signalling through C-type lectin receptors: shaping immune responses

Nature Reviews Immunology, 2009
Teunis B H Geijtenbeek
exaly  

C-type lectin receptors on dendritic cells and langerhans cells

Nature Reviews Immunology, 2002
Carl Figdor
exaly  

C-type lectin receptors in the control of T helper cell differentiation

Nature Reviews Immunology, 2016
Teunis B H Geijtenbeek
exaly  

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