Results 11 to 20 of about 115,349 (202)

Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]

International Journal of Molecular Sciences, 2012
C-type lectin receptors and their adaptor molecules are involved in the recognition of glycosylated self-antigens and pathogens. However, little is known about the species- and organ-specific expression profiles of these molecules. We therefore determined the mRNA expression levels of Dectin-1, MR1, MR2, DC-SIGN, Syk, Card-9, Bcl-10, Malt-1, Src, Dec ...
Lech, Maciej, Susanti, Heni Eka, Römmele, Christoph, Gröbmayr, Regina, Günthner, Roman, Anders, Hans-Joachim   +5 more
openaire   +5 more sources

Computational and experimental prediction of human C-type lectin receptor druggability

Frontiers in Immunology, 2014
Mammalian C-type lectin receptors are involved in many aspects of immune cell regulation such as pathogen recognition, clearance of apoptotic bodies and lymphocyte homing.
Jonas eAretz, Jonas eAretz, Eike-Christian eWamhoff, Eike-Christian eWamhoff, Jonas eHanske, Jonas eHanske, Dario eHeymann, Christoph eRademacher, Christoph eRademacher   +8 more
doaj   +2 more sources

C-type lectin receptors and RIG-I-like receptors: new points on the oncogenomics map

Cancer Management and Research, 2012
Anton G Kutikhin, Arseniy E YuzhalinDepartment of Epidemiology, Kemerovo State Medical Academy, Kemerovo, Russian FederationAbstract: The group of pattern recognition receptors includes families of Toll-like receptors, NOD-like receptors, C-type lectin ...
Yuzhalin AE, Kutikhin AG
doaj   +1 more source

Snake C-Type Lectin-Like Proteins and Platelet Receptors

Pathophysiology of Haemostasis and Thrombosis, 2005
Snake venoms are complex mixtures of biologically active proteins and peptides. Many affect haemostasis by activating or inhibiting coagulant factors or platelets, or by disrupting endothelium. Snake venom components are classified into various families, such as serine proteases, metalloproteinases, C-type lectin-like proteins, disintegrins and ...
Clemetson KJ, Lu Q, Clemetson JM
openaire   +4 more sources

Phylogenetic Analysis of C Type Lectin from Toxocara canis Infective Larvae and Comparison with the C Type Lectin Family in the Immune System of Mouse and Human

Iranian Journal of Parasitology, 2018
Background: C type lectin (CTL) family is a type of calcium-dependent proteins found in vertebrates and invertebrates. The objective of this study was to perform a comparative analysis and phylogenetic inferring for understanding the similarities and ...
Fazeleh ETEBAR, Seyed Hossein HOSSEINI, Fatemeh JALOUSIAN, Mohammad Mehdi RANJBAR   +3 more
doaj   +1 more source

C-Type Lectin Receptors in Asthma [PDF]

Frontiers in Immunology, 2018
Asthma is a heterogeneous disease that affects approximately 300 million people worldwide, largely in developed countries. The etiology of the disease is poorly understood, but is likely to involve specific innate and adaptive responses to inhaled microbial components that are found in allergens.
Sabelo Hadebe, Sabelo Hadebe, Frank Brombacher, Frank Brombacher, Gordon D. Brown, Gordon D. Brown   +5 more
openaire   +4 more sources

C-type Lectin Receptors for Tumor Eradication: Future Directions [PDF]

Cancers, 2011
Dendritic cells are key regulators in directing immune responses and therefore are under extensive research for the induction of anti-tumor responses. DCs express a large array of receptors by which they scan their surroundings for recognition and uptake of pathogens.
Streng-Ouwehand, Ingeborg, Unger, Wendy W J, Van Kooyk, Yvette   +2 more
openaire   +4 more sources

Targeting C-Type Lectin Receptors for Cancer Immunity [PDF]

Frontiers in Immunology, 2015
C-type lectin receptors (CLRs) are a large family of soluble and trans-membrane pattern recognition receptors that are widely and primarily expressed on myeloid cells. CLRs are important for cell-cell communication and host defense against pathogens through the recognition of specific carbohydrate structures. Similar to a family of Toll-like receptors,
Huimin eYan, Huimin eYan, Tomomori eKamiya, Tomomori eKamiya, Papawee eSuabjakyong, Papawee eSuabjakyong, Noriko M Tsuji   +6 more
openaire   +3 more sources

Comparative transcriptomics reveals the immune dynamics during the molting cycle of swimming crab Portunus trituberculatus

Frontiers in Immunology, 2022
Molting is one of the most important biological processes of crustacean species, and a number of molecular mechanisms facilitate this complex procedure. However, the understanding of the immune mechanisms underlying crustacean molting cycle remains very ...
Meimei Liu, Meimei Liu, Hongwei Ni, Xiaokang Zhang, Qiufeng Sun, Xugan Wu, Jie He   +6 more
doaj   +1 more source

Archaeal glycerolipids are recognized by C-type lectin receptor Mincle

, 2022
Recently, various metabolites derived from host microbes have been reported to modulate the immune system, with potential involvement in health or diseases. Archaea, prokaryotic organisms, are present in the human body, but their connection with the host
Shiori , Oka, Emi , Ito, Norihito , Arichi, Shinsuke, Inuki, Miyuki , Watanabe, Ami , Takeyama, Sho , Yamasaki, Takuro , Matsuoka, Hiroaki , Ohno   +8 more
core   +1 more source