Results 31 to 40 of about 168,647 (296)

The Third Dimension of Reading the Sugar Code by Lectins [PDF]

open access: yes, 2013
Coding of biological information is not confined to nucleic acids and proteins. Endowed with the highest level of structural versatility among biomolecules, the glycan chains of cellular glycoconjugates are well-suited to generate molecular messages ...
André, Sabine   +2 more
core   +3 more sources

DCIR suppresses osteoclastic proliferation and resorption by downregulating M-CSF and RANKL signaling

open access: yesFrontiers in Immunology, 2023
Dendritic cell immunoreceptor (DCIR) is an inhibitory C-type lectin receptor that acts as a negative regulator in the immune system and bone metabolism.
Tomonori Kaifu   +5 more
doaj   +1 more source

Characterization of the receptors for mycobacterial cord factor in Guinea pig. [PDF]

open access: yesPLoS ONE, 2014
Guinea pig is a widely used animal for research and development of tuberculosis vaccines, since its pathological disease process is similar to that present in humans.
Kenji Toyonaga   +2 more
doaj   +1 more source

From structural to functional glycomics: core substitutions as molecular switches for shape and lectin affinity of N-glycans [PDF]

open access: yes, 2009
Glycan epitopes of cellular glycoconjugates act as versatile biochemical signals (sugar coding). Here, we test the hypothesis that the common N-glycan modifications by core fucosylation and introduction of the bisecting N-acetylglucosamine moiety have ...
André, Sabine   +4 more
core   +1 more source

BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells. [PDF]

open access: yesPLoS Biology, 2007
Dendritic cells are equipped with lectin receptors to sense the extracellular environment and modulate cellular responses. Human plasmacytoid dendritic cells (pDCs) uniquely express blood dendritic cell antigen 2 (BDCA2) protein, a C-type lectin lacking ...
Wei Cao   +7 more
doaj   +1 more source

Structurally Robust and Functionally Highly Versatile—C-Type Lectin (-Related) Proteins in Snake Venoms

open access: yesToxins, 2019
Snake venoms contain an astounding variety of different proteins. Among them are numerous C-type lectin family members, which are grouped into classical Ca2+- and sugar-binding lectins and the non-sugar-binding snake venom C-type lectin-related proteins (
Johannes A. Eble
doaj   +1 more source

Investigation of asialoglycoprotein receptor glycosylation by lectin affinity methods [PDF]

open access: yesJournal of the Serbian Chemical Society, 2002
The asialoglycoprotein receptor belongs to the family of calcium-dependent (C-type) animal lectins. The purified receptor is a glycoprotein in which 10 % of the dry weight consists of sialic acid, galactose, N-acetylglucosamine and mannose.
MARGITA CUPERLOVIC   +3 more
doaj  

Dendritic Cell Activating Receptor 1 (DCAR1) Associates With FcεRIγ and Is Expressed by Myeloid Cell Subsets in the Rat

open access: yesFrontiers in Immunology, 2019
Dendritic cell activating receptor-1 (DCAR1) is a cell-surface receptor encoded by the Antigen Presenting Lectin-like gene Complex (APLEC). We generated a mouse monoclonal antibody against rat DCAR1, and used this to characterize receptor expression and ...
Michael R. Daws   +6 more
doaj   +1 more source

Antifungal immunity mediated by C-type lectin receptors may be a novel target in immunotherapy for urothelial bladder cancer

open access: yesFrontiers in Immunology, 2022
Immunotherapies, such as immune-checkpoint blockade and adoptive T-cell therapy, offer novel treatment options with good efficacy for patients with urothelial bladder cancer.
Tianhang Li   +10 more
doaj   +1 more source

Protein-carbohydrate interactions during fertilization [PDF]

open access: yes, 1998
Interaction between gametes during fertilization is at least in part regulated by carbohydrate moieties of the zona pellucida (ZP) and carbohydrate binding proteins of the sperm surface. This review focuses on the protein-carbohydrate interactions during
Kolle, S., Plendl, J., Sinowatz, Fred
core   +1 more source

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