Results 101 to 110 of about 38,504 (297)

Diazine Endo‐Functionalized Tetraphenylethylene‐Based Cyclo[6]arenes for Molecular Recognition in Both Solution and Aggregate States

Aggregate, EarlyView.
To overcome poor molecular recognition in dilute solutions of tetraphenylethylene‐embedded cyclo[6]arenes, three macrocycles with functionalized cavities featuring diazine groups as endo‐binding sites are synthesized. Their recognition affinity continuously improves with increasing hydrogen‐bond acceptance of diazine groups.
Nan Pan, Shuhong Liu, Weichen Tan, Linbin Yao, Jialin Xie, Kelong Zhu, Chunman Jia   +6 more
wiley   +1 more source

Mechanistic insights into the role of C-type lectin receptor/CARD9 signaling in human antifungal immunity

Frontiers in Cellular and Infection Microbiology, 2016
Human CARD9 deficiency is an autosomal recessive primary immunodeficiency disorder caused by biallelic mutations in the gene CARD9, which encodes a signaling protein that is found downstream of many C-type lectin receptors (CLRs).
Rebecca A. Drummond, Michail S. Lionakis
doaj   +1 more source

Identification of 35 C-Type Lectins in the Oriental Armyworm, Mythimna separata (Walker). [PDF]

Insects, 2021
Li H, Liu FF, Fu LQ, Liu Z, Zhang WT, Wang Q, Rao XJ.   +6 more
europepmc   +1 more source

Characterization of a Novel Member of the Macrophage Mannose Receptor Type C Lectin Family [PDF]

, 1996
Kai Wu, Jean Q. Yuan, Laurence A. Lasky
openalex   +1 more source

Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts

American Journal of Hematology, EarlyView.
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent, Johann Wojta, Petri T. Kovanen, Olivier Hermine, Falko Fend, Karl Sotlar, Hildegard Greinix, Klaus Geissler, Karin Hartmann, Juliana Schwaab, Marco Herling, Laura Boccuni, Lukas Kazianka, Max Vincent John, Wolfgang R. Sperr, Carina Zierfuss, Alexandar Tzankov, Christian Sillaber, Milen Minkov, Gregor Hoermann, Matthew Collin, Hans‐Peter Horny, Torsten Haferlach, Maria Sibilia, Julien Haroche, Paul La Rosée, Alberto Orfao, Michel Arock   +27 more
wiley   +1 more source

A positive feedback loop between two C-type lectins originated from gene duplication and relish promotes the expression of antimicrobial peptides in Procambarus clarkii. [PDF]

Front Immunol, 2022
Dai X, Sun M, Nie X, Zhao Y, Xu H, Han Z, Gao T, Huang X, Ren Q.   +8 more
europepmc   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2

Nature Communications, 2019
Dengue virus (DENV) promotes leukocyte-platelet interactions that contribute to pathogenesis. Here, the authors report a role for C-type lectins CLEC2 and CLEC5A in platelet activation and NET formation and show that blockade of CLEC5A and TLR2 ...
Pei-Shan Sung, Tur-Fu Huang, Shie-Liang Hsieh   +2 more
doaj   +1 more source

Mammalian Cell Surface Display as a Novel Method for Developing Engineered Lectins with Novel Characteristics

Biomolecules, 2015
Leguminous lectins have a conserved carbohydrate recognition site comprising four loops (A–D). Here, we randomly mutated the sequence and length of loops C and D of peanut agglutinin (PNA) and expressed the proteins on the surface of mouse green ...
Keisuke Soga, Hirohito Abo, Sheng-Ying Qin, Takuya Kyoutou, Keiko Hiemori, Hiroaki Tateno, Naoki Matsumoto, Jun Hirabayashi, Kazuo Yamamoto   +8 more
doaj   +1 more source

Carbohydrates from Pseudomonas aeruginosa biofilms interact with immune C-type lectins and interfere with their receptor function. [PDF]

NPJ Biofilms Microbiomes, 2021
Singh S, Almuhanna Y, Alshahrani MY, Lowman DW, Rice PJ, Gell C, Ma Z, Graves B, Jackson D, Lee K, Juarez R, Koranteng J, Muntaka S, Daniel A Mitchell, da Silva AC, Hussain F, Yilmaz G, Mastrotto F, Irie Y, Williams P, Williams DL, Cámara M, Martinez-Pomares L.   +22 more
europepmc   +1 more source