Physiological and Pathophysiological Effects of C-Type Natriuretic Peptide on the Heart [PDF]
Biology, 2022 C-type natriuretic peptide (CNP) is the third member of the natriuretic peptide family. Unlike other members, i.e., atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), which are cardiac hormones secreted from the atrium and ventricle of
Akihiro Yasoda
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C-type natriuretic peptide moderates titin-based cardiomyocyte stiffness [PDF]
JCI Insight, 2020 Heart failure is often accompanied by titin-dependent myocardial stiffness. Phosphorylation of titin by cGMP-dependent protein kinase I (PKGI) increases cardiomyocyte distensibility.
Konstanze Michel +11 more
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Dexamethasone stimulates expression of C-type Natriuretic Peptide in chondrocytes [PDF]
BMC Musculoskeletal Disorders, 2006 Background Growth of endochondral bones is regulated through the activity of cartilaginous growth plates. Disruption of the physiological patterns of chondrocyte proliferation and differentiation – such as in endocrine disorders or in many different ...
Beier Frank +2 more
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C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity [PDF]
Frontiers in Molecular Neuroscience, 2022 C-type natriuretic peptide (CNP) is highly expressed in the central nervous system (CNS) and key to neuronal development; however, a broader role for CNP in the CNS remains unclear.
Cristina Perez-Ternero +7 more
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C-Type Natriuretic Peptide Regulates the Expression and Secretion of Antibacterial Peptide S100A7 in Goat Mammary Gland Through PKG/JNK/c-Jun Signaling Pathway [PDF]
Frontiers in Veterinary Science, 2022 During infection, the infected tissue secretes a variety of endogenous peptides to resist further invasion of pathogens. Among these endogenous peptides, the natriuretic peptides and the antimicrobial peptides attracted the most attention.
Mingzhen Fan +15 more
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C-type natriuretic peptide (CNP) in the paraventricular nucleus-mediated renal sympatho-inhibition [PDF]
Frontiers in Physiology, 2023 Volume reflex produces sympatho-inhibition that is mediated by the hypothalamic paraventricular nucleus (PVN). However, the mechanisms for the sympatho-inhibitory role of the PVN and the neurochemical factors involved remain to be identified.
Hong Zheng +3 more
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Do N-Terminal Pro-C-Type Natriuretic Peptide Levels Relate to Severity of Preeclampsia? [PDF]
International Journal of Hypertension, 2020 Aim. To compare the plasma N-terminal pro-C-type natriuretic peptide concentrations of normotensive pregnant women, patients with mild preeclampsia, and patients with severe preeclampsia. Methods.
Dogan Vatansever +4 more
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Pro-C-Type Natriuretic Peptide in Women With Angina Pectoris and No Obstructive Coronary Artery Disease [PDF]
JACC: AdvancesBackground: Circulating C-type natriuretic peptides (CNPs) predict adverse outcome in women presenting with ST-elevation myocardial infarction. Objectives: The purpose of this study was to determine the prognostic impact of a high proCNP concentration in
Peter D. Mark, MD, PhD +5 more
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C-type natriuretic peptide: the heart's guardian angel. [PDF]
Eur Heart J, 2020 Abstract
Sangaralingham SJ, Chen Y, Burnett JC.
europepmc +3 more sources
The role of C-type natriuretic peptide in cardiovascular medicine [PDF]
European Heart Journal, 2001 0195-668X/01/120997+11 $35.00/0 conventional drug therapy, in order to reduce plasma aminoterminal BNP levels, resulted in reduced total cardiovascular events when compared to therapy directed by clinical acumen. Much less is known about C-type natriuretic peptide (CNP) which was first isolated from porcine brain in 1990. It is now known that CNP has a
Paul R. Kalra
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