Results 1 to 10 of about 66,518 (227)

C-Type Natriuretic Peptide Regulates the Expression and Secretion of Antibacterial Peptide S100A7 in Goat Mammary Gland Through PKG/JNK/c-Jun Signaling Pathway [PDF]

Frontiers in Veterinary Science, 2022
During infection, the infected tissue secretes a variety of endogenous peptides to resist further invasion of pathogens. Among these endogenous peptides, the natriuretic peptides and the antimicrobial peptides attracted the most attention.
Mingzhen Fan, Mingzhen Fan, Yuyang Miao, Yuyang Miao, Yutong Yan, Yutong Yan, Kunyuan Zhu, Kunyuan Zhu, Xiaoe Zhao, Xiaoe Zhao, Menghao Pan, Menghao Pan, Baohua Ma, Baohua Ma, Qiang Wei, Qiang Wei   +15 more
doaj   +4 more sources

Pro-C-Type Natriuretic Peptide in Women With Angina Pectoris and No Obstructive Coronary Artery Disease [PDF]

JACC: Advances
Background: Circulating C-type natriuretic peptides (CNPs) predict adverse outcome in women presenting with ST-elevation myocardial infarction. Objectives: The purpose of this study was to determine the prognostic impact of a high proCNP concentration in
Peter D. Mark, MD, PhD, Jakob Schroder, MD, Andreas K. Jensen, MD, Timothy C.R. Prickett, PhD, Eva Prescott, MD, DMSc, Jens P. Goetze, MD, DMSc   +5 more
doaj   +3 more sources

C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity [PDF]

Frontiers in Molecular Neuroscience, 2022
C-type natriuretic peptide (CNP) is highly expressed in the central nervous system (CNS) and key to neuronal development; however, a broader role for CNP in the CNS remains unclear.
Cristina Perez-Ternero, Patrick N. Pallier, Jordi L. Tremoleda, Alessio Delogu, Cathy Fernandes, Cathy Fernandes, Adina T. Michael-Titus, Adrian J. Hobbs   +7 more
doaj   +3 more sources

Perspectives on C‐Type Natriuretic Peptide in Cardiometabolic Disease [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Although CNP (C‐type natriuretic peptide) was first identified in brain tissue, its systemic expression and release is mainly located to the endothelial lining of the vasculature.
Jens P. Goetze, Hiromu Yanagisawa, Hideyuki Kinoshita, John Burnett, Michael Nyberg, Toshio Nishikimi   +5 more
doaj   +2 more sources

Physiological and Pathophysiological Effects of C-Type Natriuretic Peptide on the Heart [PDF]

Biology, 2022
C-type natriuretic peptide (CNP) is the third member of the natriuretic peptide family. Unlike other members, i.e., atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), which are cardiac hormones secreted from the atrium and ventricle of
Akihiro Yasoda
doaj   +2 more sources

Do N-Terminal Pro-C-Type Natriuretic Peptide Levels Relate to Severity of Preeclampsia? [PDF]

International Journal of Hypertension, 2020
Aim. To compare the plasma N-terminal pro-C-type natriuretic peptide concentrations of normotensive pregnant women, patients with mild preeclampsia, and patients with severe preeclampsia. Methods.
Dogan Vatansever, Pınar Vatansever, Burak Giray, A. Aktug Ertekin, Serpil Bilsel   +4 more
doaj   +2 more sources

C-type natriuretic peptide (CNP) in the paraventricular nucleus-mediated renal sympatho-inhibition [PDF]

Frontiers in Physiology, 2023
Volume reflex produces sympatho-inhibition that is mediated by the hypothalamic paraventricular nucleus (PVN). However, the mechanisms for the sympatho-inhibitory role of the PVN and the neurochemical factors involved remain to be identified.
Hong Zheng, Tapan A. Patel, Xuefei Liu, Kaushik P. Patel   +3 more
doaj   +2 more sources

C-type natriuretic peptide moderates titin-based cardiomyocyte stiffness [PDF]

JCI Insight, 2020
Heart failure is often accompanied by titin-dependent myocardial stiffness. Phosphorylation of titin by cGMP-dependent protein kinase I (PKGI) increases cardiomyocyte distensibility.
Konstanze Michel, Melissa Herwig, Franziska Werner, Katarina Špiranec Spes, Marco Abeßer, Kai Schuh, Swati Dabral, Andreas Mügge, Hideo A. Baba, Boris V. Skryabin, Nazha Hamdani, Michaela Kuhn   +11 more
doaj   +2 more sources

C-type natriuretic peptide regulates lipid metabolism through a NPRB-PPAR pathway in the intramuscular and subcutaneous adipocytes in chickens [PDF]

Scientific Reports
Natriuretic peptides (NPs) have an important role in lipid metabolism in skeletal muscle and adipose tissue in animals. C-type natriuretic peptide (CNP) is an important NP, but the molecular mechanisms that underlie its activity are not completely ...
Huayun Huang, Longzhou Liu, Zhong Liang, Qianbao Wang, Chunmiao Li, Zhengyang Huang, Zhenhua Zhao, Wei Han   +7 more
doaj   +2 more sources

C‐type natriuretic peptide promotes human granulosa cell growth and estradiol production: Implications for early follicle development [PDF]

Reproductive Medicine and Biology
Purpose To investigate the effects of C‐type natriuretic peptide (CNP) on human granulosa cell growth and elucidate its regulatory mechanisms. Methods A human non‐luteinizing granulosa cell line (HGrC) developed from small antral follicles was used to ...
Yorino Sato, Kazuhiro Kawamura
doaj   +2 more sources