Results 191 to 200 of about 66,518 (227)

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Restoration of C-type natriuretic peptide and glial fibrillary acidic protein expression in fear centers and intrinsic cardiac ganglia by theta frequency sound during chronic stress in mice

Sana Ahmed, Meha Fatima Aftab, Nazia Ahmed, Imran M. Yusuf, M. Sameer Qureshi   +4 more
openalex   +1 more source

Cystatin C–based CKD‐EPI Equations and N‐Terminal Pro‐B‐Type Natriuretic Peptide for Predicting Outcomes in Acutely Decompensated Heart Failure [PDF]

, 2015
Pedro J. Flores‐Blanco, Sergio Manzano‐Fernández, Juan Ignacio Pérez‐Calvo, Francisco J. Pastor‐Pérez, Francisco José Ruiz-Ruiz, Francisco Javier Carrasco-Sánchez, José Luís Morales‐Rull, Domingo A. Pascual‐Figal, Luis Galisteo‐Almeda, James L. Januzzi   +9 more
openalex   +1 more source

Comparative effectiveness of pharmacotherapy for heart failure with preserved ejection fraction: A systematic review and network meta‐analysis

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aim Heart failure with preserved ejection fraction (HFpEF) presents a therapeutic challenge, characterised by a paucity of validated treatments. Emerging data suggest that targeting adiposity is central to HFpEF pathogenesis. We conducted an updated network meta‐analysis to compare the efficacy of emerging and established HFpEF therapies ...
Szu‐Han Chen, Yu‐Wen Tseng, Chi‐Jung Huang, Shu‐Mei Yang, Marat Fudim, Shao‐Yuan Chuang, Shih‐Hsien Sung, Hao‐Min Cheng   +7 more
wiley   +1 more source

Effects of sotagliflozin on markers of volume status and sodium handling in patients with type 1 diabetes: A biomarker analysis of the inTandem3 clinical trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Sotagliflozin, an inhibitor of sodium‐glucose co‐transporter (SGLT)‐1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was assessed on markers of neurohormone activation and volume homeostasis in patients with type 1 diabetes (T1D).
Massimo Nardone, Erik Moedt, Hiddo J. L. Heerspink, Michael J. Davies, Manon Girard, David Z. I. Cherney, Marcel H. A. Muskiet   +6 more
wiley   +1 more source

Sacubitril/Valsartan Attenuates Inflammation and Fibrosis Associated With Decreased Integrin α8 and Inhibits Hepatocarcinogenesis in a Rat Model of Metabolic Dysfunction‐Associated Steatohepatitis

Hepatology Research, EarlyView.
Sacubitril/Valsartan (Sac/Val) alleviates fibrosis and inflammation in metabolic dysfunction‐associated steatohepatitis (MASH). Its anti‐fibrotic effect is linked to the suppression of Integrin alpha 8 (Itga8), a protein crucial for hepatic stellate cell (HSC) activation and collagen production.
Hayato Kawamura, Aya Naiki‐Ito, Xiaochen Kuang, Akihiro Murakami, Masayuki Komura, Takanori Suzuki, Hiroyuki Kato, Yuko Nagayasu, Kentaro Matsuura, Kei Fujiwara, Hiromi Kataoka, Satoru Takahashi   +11 more
wiley   +1 more source

ASB20123: A novel C-type natriuretic peptide derivative for treatment of growth failure and dwarfism

, 2019
Naomi Morozumi, Takafumi Yotsumoto, Akira Yamaki, Kazunori Yoshikiyo, Sayaka Yoshida, Ryuichi Nakamura, Toshimasa Jindo, Mayumi Furuya, Hiroaki Maeda, Yoshiharu Minamitake, Kenji Kangawa   +10 more
openalex   +2 more sources

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

International Journal of Dermatology, EarlyView.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska, Isha Gandhi, Robert Adler, Deena Fayyad, Perya Bhagchandani, Shabnam Afzal, Waleed Adawi, Shivani Patel, Shawn G. Kwatra   +8 more
wiley   +1 more source

Cost‐Utility Analysis of Left Bundle Branch Area Versus Biventricular Pacing for Cardiac Resynchronization Therapy: A Multicenter, Prospective, Quasi‐Experimental Study

Journal of Cardiovascular Electrophysiology, EarlyView.
Cost‐utility of LBBAP CRT versus BVP CRT. ABSTRACT Introduction Cardiac resynchronization therapy (CRT) is a well‐established treatment for patients with heart failure (HF). Recently, left bundle branch area pacing (LBBAP) has emerged as a more physiological alternative to biventricular pacing (BVP) for CRT.
José M. Sánchez‐Moreno, Leticia García‐Mochón, Manuel Molina‐Lerma, Guillermo Gutiérrez‐Ballesteros, Manuel Frutos‐López, Ricardo Pavón‐Jiménez, M. C. Olvera‐Porcel, Juan Jiménez‐Jáimez, Miguel Álvarez   +8 more
wiley   +1 more source

C-type natriuretic peptide co-ordinates cardiac structure and function. [PDF]

Eur Heart J, 2020
Moyes AJ, Chu SM, Aubdool AA, Dukinfield MS, Margulies KB, Bedi KC, Hodivala-Dilke K, Baliga RS, Hobbs AJ.   +8 more
europepmc   +1 more source