Results 21 to 30 of about 66,518 (227)

Auto/Paracrine C-Type Natriuretic Peptide/Cyclic GMP Signaling Prevents Endothelial Dysfunction. [PDF]

Int J Mol Sci
Werner F, Naruke T, Sülzenbrück L, Schäfer S, Rösch M, Völker K, Krebes L, Abeßer M, Möllmann D, Baba HA, Schweda F, Zernecke A, Kuhn M.   +12 more
europepmc   +3 more sources

Molecular Mechanism of Blood Pressure Regulation through the Atrial Natriuretic Peptide

Biology, 2022
Natriuretic peptides, including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), have cardioprotective effects and regulate blood pressure in mammals.
Takeshi Tokudome, Kentaro Otani
doaj   +1 more source

AC-NP: a novel chimeric peptide with natriuretic and vasorelaxing actions. [PDF]

PLoS ONE, 2011
The aim of this study was to evaluate the cardiovascular and renal activities of a newly designed natriuretic peptide (NP). Here, we engineered a novel 28-amino acid chimeric peptide, termed AC-NP that combined the 17-amino acid ring of C type ...
Bao-Ying Chen, Jian-Kang Chen, Miao-Zhang Zhu, Dong-Liang Zhang, Jie-Shen Sun, Jian-Ming Pei, Hua-Song Feng, Xiao-Xing Zhu, Jian Jin, Jun Yu   +9 more
doaj   +1 more source

Roles of Natriuretic Peptides and the Significance of Neprilysin in Cardiovascular Diseases

Biology, 2022
Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) activate the guanylyl cyclase A receptor (GC-A), which synthesizes the second messenger cGMP in a wide variety of tissues and cells.
Hitoshi Nakagawa, Yoshihiko Saito
doaj   +1 more source

Factors influencing left ventricular ejection fraction in patients with coronary microvascular disease and obstructive coronary artery disease

BMC Research Notes, 2020
Objective The aim of our research was to evaluate the relationship involving left ventricular ejection fraction, low density lipoprotein, B-type natriuretic peptide, Troponin I and coronary flow reserve, and to determine the predictors of left ...
Henry Anselmo Mayala, Magesa Mafuru, Abdalah Mkangala, Mark Mayala, Pedro Pallangyo, Dickson Minja, Mohamed Janabi, Wang Zhao-hui   +7 more
doaj   +1 more source

Natriuretic peptides: Diagnostic and therapeutic use

Indian Journal of Endocrinology and Metabolism, 2011
Natriuretic peptides (NPs) are hormones which are mainly secreted from heart and have important natriuretic and kaliuretic properties. There are four different groups NPs identified till date [atrial natriuretic peptide (ANP), B-type natriuretic peptide (
Kaushik Pandit, Pradip Mukhopadhyay, Sujoy Ghosh, Subhankar Chowdhury   +3 more
doaj   +1 more source

CNP, the Third Natriuretic Peptide: Its Biology and Significance to the Cardiovascular System

Biology, 2022
The natriuretic peptide family consists of three biologically active peptides: ANP, BNP, and CNP. CNP is more widely expressed than the other two peptides, with significant levels in the central nervous system, osteochondral system, and vascular system ...
Yasuaki Nakagawa, Toshio Nishikimi
doaj   +1 more source

Framingham and American College of Cardiology/American Heart Association Pooled Cohort Equations, High‐Sensitivity Troponin T, and N‐Terminal Pro–Brain‐Type Natriuretic Peptide for Predicting Atherosclerotic Cardiovascular Events Across the Spectrum of Kidney Dysfunction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Contemporary guidelines recommend using atherosclerotic cardiovascular disease screening tools to guide primary prevention. The performance of these scores is not well known in patients with moderate to advanced chronic kidney disease ...
Benjamin Lidgard, Leila R. Zelnick, Alan Go, Kevin D. O’Brien, Nisha Bansal   +4 more
doaj   +1 more source

The oocyte cumulus complex regulates mouse sperm migration in the oviduct

Communications Biology, 2022
Oocyte-dependent and cumulus cell-derived transforming growth factor-β promotes natriuretic peptide type C expression in mouse ampullary epithelial cells, which promotes sperm migration into the ampulla for fertilization.
Zhijuan Wang, Hongwei Wei, Zhanying Wu, Xiaodan Zhang, Yanli Sun, Longwei Gao, Wenqing Zhang, You-Qiang Su, Meijia Zhang   +8 more
doaj   +1 more source

Dexamethasone stimulates expression of C-type Natriuretic Peptide in chondrocytes

BMC Musculoskeletal Disorders, 2006
Background Growth of endochondral bones is regulated through the activity of cartilaginous growth plates. Disruption of the physiological patterns of chondrocyte proliferation and differentiation – such as in endocrine disorders or in many different ...
Beier Frank, Baybayan Laurie, Agoston Hanga   +2 more
doaj   +1 more source