Results 81 to 90 of about 18,984,511 (231)

Perioperative Risks of Concurrent Pancreatic and Hepatic Resections for Neuroendocrine Tumors

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Pancreatic neuroendocrine tumors (pNETs) account for 1%–2% of pancreatic tumors, with an increasing incidence. The safety of concurrent pancreas‐liver resections remains uncertain. This study evaluated the national outcomes of concurrent pancreatectomy and liver‐directed surgery for pNETs. Methods ACS‐NSQIP (2019–2023)
Amir Ebadinejad, Ashrita Raghuram, Sophia Xiao, Ethan Angle, Hassan Aziz   +4 more
wiley   +1 more source

Investigational Treatment Agents for Recurrent Clostridioides difficile Infection (rCDI)

Journal of Experimental Pharmacology, 2020
Ravina Kullar,1 Mai-Chi N Tran,2,3 Ellie JC Goldstein4,5 1Expert Stewardship, Inc., Newport Beach, CA, USA; 2Pharmacy Department, Keck Medical Center of USC, Los Angeles, CA, USA; 3Clinica Juan Pablo Medical Group, Los Angeles, CA, USA; 4R.M.
Kullar R, Tran MCN, Goldstein EJC
doaj  

Transoral Robotic Surgery in Head and Neck Oncology: A Scoping Review of Evidence, Technological Advancements, and Future Trajectories

Journal of Surgical Oncology, EarlyView.
ABSTRACT Robotic surgery has transformed head and neck cancer (HNC) treatment. This scoping review synthesizes evidence on transoral robotic surgery (TORS), focusing on applications, limitations, and future directions. Following PRISMA‐ScR guidelines, this review used the PCC framework (Population: HNC patients; Concept: technological advancements ...
Anna Luíza Damaceno Araújo, Karthik N. Rao, Juan P. Rodrigo, Vincent Vander Poorten, Orlando Guntinas‐Lichius, Alfio Ferlito, Luiz Paulo Kowalski   +6 more
wiley   +1 more source

Clostridioides difficile colonization is not mediated by bile salts and utilizes Stickland fermentation of proline in an in vitro model

mSphere
Treatment with antibiotics is a major risk factor for Clostridioides difficile infection, likely due to depletion of the gastrointestinal microbiota. Two microbiota-mediated mechanisms thought to limit C.
Xiaoyun Huang, April E. Johnson, Joshua N. Brehm, Thi Van Thanh Do, Thomas A. Auchtung, Hugh C. McCullough, Armando I. Lerma, Sigmund J. Haidacher, Kathleen M. Hoch, Thomas D. Horvath, Joseph A. Sorg, Anthony M. Haag, Jennifer M. Auchtung   +12 more
doaj   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Long‐term outcomes of haploidentical hematopoietic stem cell transplantation with antithymocyte globulin–based myeloablative conditioning in pediatric refractory or relapsed non‐Hodgkin lymphoma

Pediatric Investigation, EarlyView.
Single‐center retrospective data showed that ATG‐based myeloablative haploidentical hematopoietic stem cell transplantation provides durable remission and favorable long‐term survival in children with refractory/relapsed non‐Hodgkin lymphoma, achieving high engraftment rates, low relapse incidence, and acceptable toxicity.
Chenguang Jia, Jie Zheng, Meng Yuan, Hongbo He, Yibo Fan, Bin Wang, Guanghua Zhu, Jun Yang, Yanhui Luo, Lixiao Cai, Pan Zhang, Yanlong Duan, Maoquan Qin   +12 more
wiley   +1 more source

Catechins and Their Effect on the Gut Microbiome in Health and Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika, Bindu Sadanandan, Honnamachanahalli Ramachandraiah Tejashree, Maitreyi Darbha, Kirti Gupta, Srinivas Reneeka   +5 more
wiley   +1 more source

Proteomics as a tool for the characterisation of nosocomial pathogens [PDF]

, 2010
The aim of the present investigation was to develop and assess the potential of various proteomic approaches for the characterisation of two major nosocomial pathogens, S. aureus and C. difficile and to further investigate the intraspecies diversity of C.
Rajakaruna, LK
core  

Few Annotations, High Accuracy: Transfer Learning and Data Augmentation Improve Passive Acoustic Monitoring of the Vulnerable African Manatee

Remote Sensing in Ecology and Conservation, EarlyView.
Can deep learning reliably detect a threatened species in passive acoustic monitoring with few annotations? Across 52 sites and 600 recording days, we compared two deep learning recognizers with the traditional machine learning Kaleidoscope for detecting African manatee vocalizations.
Lucas Dubus, Auguste Verdier, Nina Giotto, Grace Mbemba, Gabriel Michelin, Baptiste Mulot, Stéphanie Manel, David Mouillot   +7 more
wiley   +1 more source

Lactobacillus delbrueckii ssp. bulgaricus B-30892 can inhibit cytotoxic effects and adhesion of pathogenic Clostridium difficile to Caco-2 cells

Gut Pathogens, 2009
Background Probiotic microorganisms are receiving increasing interest for use in the prevention, treatment, or dietary management of certain diseases, including antibiotic-associated diarrhea (AAD).
Banerjee Pratik, Merkel Glenn J, Bhunia Arun K   +2 more
doaj   +1 more source