Results 11 to 20 of about 302,633 (300)

Probiotic Lacticaseibacillus rhamnosus GG Increased Longevity and Resistance Against Foodborne Pathogens in Caenorhabditis elegans by Regulating MicroRNA miR-34

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
In this study, we investigated the relation of probiotic activity of Lacticaseibacillus rhamnosus strain GG (LGG) and expression of microRNA to immune response and longevity in Caenorhabditis elegans host model. First, we evaluated the survival rate of C.
Bohyun Yun   +6 more
doaj   +1 more source

Caenorhabditis Elegans Exhibits Morphine Addiction-like Behavior via the Opioid-like Receptor NPR-17

open access: yesFrontiers in Pharmacology, 2022
Addiction has become a profound societal problem worldwide, and few effective treatments are available. The nematode Caenorhabditis elegans (C. elegans) is an excellent invertebrate model to study neurobiological disease states. C.
Soichiro Ide   +3 more
doaj   +1 more source

Gastrulation in C. elegans [PDF]

open access: yesWormBook, 2005
Gastrulation is the process by which the germ layers become positioned in an embryo. C. elegans gastrulation serves as a model for studying the molecular mechanisms of diverse cellular and developmental phenomena, including morphogenesis, cell polarization, cell-cell signaling, actomyosin contraction and cell-cell adhesion.
Jeremy, Nance   +2 more
openaire   +2 more sources

Lactic acid bacteria that activate immune gene expression in Caenorhabditis elegans can antagonise Campylobacter jejuni infection in nematodes, chickens and mice

open access: yesBMC Microbiology, 2021
Background Campylobacter jejuni is the major micro-bacillary pathogen responsible for human coloenteritis. Lactic acid bacteria (LAB) have been shown to protect against Campylobacter infection. However, LAB with a good ability to inhibit the growth of C.
Xing Jin   +8 more
doaj   +1 more source

Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin

open access: yesDisease Models & Mechanisms, 2018
Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely the onset of resistance to the ...
Francisco Javier García-Rodríguez   +10 more
doaj   +1 more source

The genome of Romanomermis culicivorax:revealing fundamental changes in the core developmental genetic toolkit in Nematoda [PDF]

open access: yes, 2013
Background: The genetics of development in the nematode Caenorhabditis elegans has been described in exquisite detail. The phylum Nematoda has two classes: Chromadorea (which includes C. elegans) and the Enoplea.
Altmüller, Janine   +15 more
core   +2 more sources

Homologous and unique G protein alpha subunits in the nematode Caenorhabditis elegans [PDF]

open access: yes, 1991
A cDNA corresponding to a known G protein alpha subunit, the alpha subunit of Go (Go alpha), was isolated and sequenced. The predicted amino acid sequence of C. elegans Go alpha is 80-87% identical to other Go alpha sequences.
Lochrie, Michael A.   +3 more
core   +1 more source

Autophagy in C. elegans [PDF]

open access: yesWormBook, 2009
Autophagy is a ubiquitous cellular process responsible for the bulk degradation of cytoplasmic components through an autophagosomal-lysosomal pathway. Genetic screens, primarily in S. cerevisiae, have identified numerous genes that are essential for autophagy. Many of these genes have orthologs in higher eukaryotes, including C.
Alicia, Meléndez, Beth, Levine
openaire   +2 more sources

WormBase 2007 [PDF]

open access: yes, 2008
WormBase (www.wormbase.org) is the major publicly available database of information about Caenorhabditis elegans, an important system for basic biological and biomedical research. Derived from the initial ACeDB database of C. elegans genetic and sequence
A. Petcherski   +51 more
core   +3 more sources

High-throughput isolation and mapping of C. elegans mutants susceptible to pathogen infection. [PDF]

open access: yesPLoS ONE, 2008
We present a novel strategy that uses high-throughput methods of isolating and mapping C. elegans mutants susceptible to pathogen infection. We show that C.
Laura E Fuhrman   +2 more
doaj   +1 more source

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