Results 191 to 200 of about 3,095,271 (376)

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

C1 inhibitor and prolylcarboxypeptidase modulate prekallikrein activation on endothelial cells. [PDF]

J Allergy Clin Immunol, 2023
Merkulova AA, Abdalian S, Silbak S, Pinheiro A, Schmaier AH.   +4 more
europepmc   +1 more source

Recombinant human C1 esterase inhibitor (Conestat alfa) for prophylaxis to prevent attacks in adult and adolescent patients with hereditary angioedema

, 2018
Anna Valerieva, Sonia Caccia, Marco Cicardi   +2 more
openalex   +2 more sources

In pursuit of excellence: an integrated care pathway for C1 inhibitor deficiency [PDF]

, 2013
A L Manson, Amy Price, John Dempster, P Clinton-Tarestad, C Greening, R Enti, Sean Hill, Sofia Grigoriadou, Matthew Buckland, Hilary Longhurst   +9 more
openalex   +1 more source

Long term follow-up of complement parameters to improve the management of acquired angioedema due to C1-inhibitor deficiency

, 2022
Zsófia Pólai, Zsuzsanna Balla, Lilian Varga, Szabolcs Benedek, Henriette Farkas   +4 more
openalex   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

Investigating Mitochondrial Viscosity in Ferroptosis‐Mediated Drug‐Induced Liver Injury using a Double‐Targeted Strategy

Advanced Science, EarlyView.
Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou, Yan Wang, Bing Huang, Hosoowi Lee, Mei Yan, Juyoung Yoon   +5 more
wiley   +1 more source

Recombinant human C1-esterase inhibitor for the prevention of acute hereditary angioedema attacks: a case report [PDF]

, 2018
Arthur B. Vegh, N. Park, T. Cantwell
openalex   +1 more source

All‐Round Talent: Unique Zinc Guanidine Catalyst Performs Efficiently in Synthesis and Chemical Recycling of (Bio)Polyesters

Advanced Science, EarlyView.
A new zinc hybrid guanidine catalyst [Zn{(R,R)TMGNMe2(1,2)ch}2](OTf)2 (C1) shows very high catalytic activity in the polymerization of cyclic esters and in the depolymerization of these polyesters. Using C1 in the ring‐opening polymerization of lactide and caprolactone under industrially relevant conditions, astonishing rate constants of the same order
Tabea Becker, Koki Takeuchi, Carolin Süßmuth, Frederico Boekhoff, Martin A. Schäfer, Shunsuke Kato, Alexander Hoffmann, Takashi Hayashi, Sonja Herres‐Pawlis   +8 more
wiley   +1 more source

Upregulation of C1-inhibitor in pancreatic cancer [PDF]

, 2019
Kurt Osther, Karolina Förnvik, Emma Liljedahl, Leif G. Salford, Henrietta Nittby Redebrandt   +4 more
openalex   +1 more source