Results 201 to 210 of about 721,729 (294)

Recurrent Intestinal Angioedema with Normal C1-Inhibitor: A Case Report. [PDF]

Medicina (Kaunas)
Jevtic D, Taylor A, Dumic I, Sviggum E, Nordstrom CW, Antic M.   +5 more
europepmc   +1 more source

Dynamic Reconstruction‐Engineered Heterointerfaces for Acidic Hydrogen Evolution at Ampere‐Level Current Density

Advanced Science, EarlyView.
A dynamic reconstruction strategy was utilized to construct PtCu/Cu3P heterostructures on the surface of self‐supporting Cu3P nanowires. The loose porosity in the restructured layer, together with a dynamic “dissolution‐redeposition” equilibrium during electrocatalysis, enables the electrode to maintain a low, stable overpotential for 240 h at ampere ...
Kaixi Wang, Yunshan Zheng, Chengzong Yuan, Kwun Nam Hui   +3 more
wiley   +1 more source

Global frequency, diagnosis, and treatment of hereditary angioedema with normal C1 inhibitor. [PDF]

J Allergy Clin Immunol Glob
Magerl M, Riedl MA, Arruda LK, Bauer A, Berardi A, Bernstein JA, Bouillet L, Buckland M, Buttgereit T, Cohn DM, Craig T, Criado RF, Du-Thanh A, Fain O, Gonçalo M, Greve J, Grumach AS, Guilarte M, Katelaris C, Kinaciyan T, Latysheva EA, Lleonart R, Llosa OC, Mansour E, Grivcheva-Panovska V, Parisi C, Rosario Filho NA, Santos AS, Staubach P, Valerieva A, Rodrigues Valle SO, Danese S, Ulloa J, Audhya PK, Maurer M.   +34 more
europepmc   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

One-year real-life outcomes of lanadelumab therapy in Romanian patients with hereditary angioedema due to C1-inhibitor deficiency. [PDF]

Front Allergy
Bara NA, Nădășan V, Deleanu D.
europepmc   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

Abstracts of the 14th C1-inhibitor Deficiency and Angioedema Workshop. [PDF]

Allergy Asthma Clin Immunol
europepmc   +1 more source

AI‐Assisted Digital Single‐Molecule Activity Tracker for Decoupling Intrinsic Heterogeneity from Photo‐Oxidative Damage in High‐Photon‐Flux Enzymology

Advanced Science, EarlyView.
Employing a digital single‐molecule activity tracker (dSMAT), this research demonstrates that high‐photon‐flux irradiation drives progressive oxidative scarring in polymerases. Unlike simple thermal denaturation, real‐time kinetic tracking dynamically visualizes enzymes degrading into multiple impaired subpopulations.
Anran Zheng, Qi Yang, Jinze Li, Fuqiang Ma, Xuefeng Wang, Zhen Guo, Chuanyu Li, Dongshu Li, Jia Yao, Zhiqi Zhang, Wei Zhang, Lianqun Zhou   +11 more
wiley   +1 more source

Hereditary angioedema due to C1-inhibitor deficiency: current therapeutic approaches. [PDF]

Curr Opin Allergy Clin Immunol
Costanzo G, Sambugaro G, Firinu D.
europepmc   +1 more source

Machine Learning‐Assisted Design and Performance Prediction of a Compact Dual‐Band Polarization‐Insensitive THz Metamaterial Absorber for Skin‐Cancer‐Related Refractive‐Index Sensing

Advanced Electronic Materials, EarlyView.
A compact QASRR‐based THz metamaterial absorber enables polarization‐insensitive dual‐band absorption and skin‐cancer‐related refractive‐index sensing through measurable resonance shifts. Field, surface‐current, and circuit analyses clarify the dual‐resonance mechanism, while StackNet‐assisted prediction accurately estimates the simulated absorption ...
Md. Murad Kabir Nipun, S. M. Rifatur Rana, Md. Golam Morshed, Imrose Jahan, F. A. Sabbir Ahamed, Md. Jahedul Islam   +5 more
wiley   +1 more source