Results 241 to 250 of about 3,095,271 (376)

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source

Recurrent Intestinal Angioedema with Normal C1-Inhibitor: A Case Report. [PDF]

Medicina (Kaunas)
Jevtic D, Taylor A, Dumic I, Sviggum E, Nordstrom CW, Antic M.   +5 more
europepmc   +1 more source

The Role of Bradykinin Receptors in Hereditary Angioedema Due to C1-Inhibitor Deficiency. [PDF]

Int J Mol Sci, 2022
Dyga W, Obtulowicz A, Mikolajczyk T, Bogdali A, Dubiela P, Obtulowicz K.   +5 more
europepmc   +1 more source

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

Advanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han, Qin Yuan, Zhu Wu, Yaohui Fang, Hong Qian, Jiale Zhu, Yuchen Zhang, Ke Deng, Liangliang Su, Haibo Xu, Haotian Shu, Yiming Gong, Qiaoqiao Xu, Guizhen Du, Di Wu, Yun Fan, Chuncheng Lu   +16 more
wiley   +1 more source

One-year real-life outcomes of lanadelumab therapy in Romanian patients with hereditary angioedema due to C1-inhibitor deficiency. [PDF]

Front Allergy
Bara NA, Nădășan V, Deleanu D.
europepmc   +1 more source

PSY27 A Cost-Effectiveness Comparison of Icatibant and C1-Esterase Inhibitor Concentrate for the Symptomatic Treatment of Acute Attacks of Types I and II Hereditary Angioedema in the UK Setting [PDF]

, 2012
MATTHEW HELBERT, Feng Pang, M. Alvarez-Reyes, I. Pearson, Sorrel Wolowacz, Lavanya Diwakar   +5 more
openalex   +1 more source

C1-Inhibitor Treatment Decreases Renal Injury in an Established Brain-Dead Rat Model

Transplantation, 2017
Felix Poppelaars, Neeltina M. Jager, J. Kotimaa, H. Leuvenink, M. Daha, C. van Kooten, M. Seelen, J. Damman   +7 more
semanticscholar   +1 more source

Broadband All‐Optical Memtransistor Based on Organic Cocrystals for Noise‐Robust Motion Recognition

Advanced Science, EarlyView.
This work presents an all‐optical synaptic transistor using DTT‐TCNQ organic charge transfer cocrystals, achieving broadband bidirectional modulation (395–808 nm) with highly linear synaptic plasticity (nonlinearity coefficients αp = 0.00191, αd = 0.00305).
Zhaohui Cai, Yuxiao Fang, Wenjie Du, Zhengjun Liu, Yingli Shi, Jiahua Luo, Rui Wu, Lixing Kang, Chun Zhao   +8 more
wiley   +1 more source

Global frequency, diagnosis, and treatment of hereditary angioedema with normal C1 inhibitor. [PDF]

J Allergy Clin Immunol Glob
Magerl M, Riedl MA, Arruda LK, Bauer A, Berardi A, Bernstein JA, Bouillet L, Buckland M, Buttgereit T, Cohn DM, Craig T, Criado RF, Du-Thanh A, Fain O, Gonçalo M, Greve J, Grumach AS, Guilarte M, Katelaris C, Kinaciyan T, Latysheva EA, Lleonart R, Llosa OC, Mansour E, Grivcheva-Panovska V, Parisi C, Rosario Filho NA, Santos AS, Staubach P, Valerieva A, Rodrigues Valle SO, Danese S, Ulloa J, Audhya PK, Maurer M.   +34 more
europepmc   +1 more source

Pregnancy in Patients With Hereditary Angioedema and Normal C1 Inhibitor. [PDF]

Front Allergy, 2022
Gabriel N, Marcelino F, Ferriani MPL, Arruda LK, Campos RA, Gonçalves RF, Chong-Neto H, Rosario Filho N, Valle SOR, Pesquero JB, Grumach AS.   +10 more
europepmc   +1 more source