Results 41 to 50 of about 117,459 (333)

Regulation of C1 Inhibitor Synthesis

Immunobiology, 1998
The primary biologic roles of C1 inhibitor (C1-INH) are the regulation of activation of the classical complement pathway and of the contact system of kinin formation. Heterozygosity for deficiency or dysfunction of C1-INH results in hereditary angioedema (HAE).
Kamyar Zahedi, Anne E. Prada, Alvin E. Davis   +2 more
openaire   +2 more sources

C1-Inhibitor and Transplantation

Immunobiology, 2002
Excessive activation of the protein cascade systems has been associated with post-transplantation inflammatory disorders. There is increasing evidence that complement not only significantly contributes to ischemia/reperfusion injury upon cold storage of the organ but also, although to a different degree, to allograft rejection. Complement activation is
openaire   +3 more sources

Acquired Form of Angioedema of the Head and Neck Related to a Deficiency in C1-Inhibitor: A Case Report with a Review of the Literature

Case Reports in Otolaryngology, 2012
Angioedema related to a deficiency in the C1-inhibitor protein is characterized by its lack of response to therapies including antihistamine, steroids, and epinephrine. In the case of laryngeal edema, mortality rate is approximately 30 percent. The first
Bassel Hallak, Propser Konu, Florian Lang, Christian Simon, Philippe Monnier   +4 more
doaj   +1 more source

A danazolkezelés hatása C1-inhibitor-hiány okozta hereditaer angiooedemás gyermekek növekedésére [PDF]

, 2017
Absztrakt: Bevezetés: Az attenuált androgéneket gyakran alkalmazzák C1-inhibitor-hiányos hereditaer angiooedema akut epizódjainak megelőzésére. Praepubertason túli alkalmazásuk az epifízisfugák
Farkas, Henriette, Kőhalmi, Kinga Viktória, Luczay, Andrea, Varga, Lilian, Veszeli, Nóra   +4 more
core   +2 more sources

Recombinant and Plasma-Purified Human C1 Inhibitor for the Treatment of Hereditary Angioedema

World Allergy Organization Journal, 2010
Background Agents for prophylaxis of hereditary angioedema (HAE) have been available in the United States for several decades, but their usefulness is limited by side effects and they cannot be used at all in some patients.
Michael M Frank, MD
doaj   +1 more source

International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1-Inhibitor deficiency [PDF]

, 2016
BACKGROUND: The consensus documents published to date on hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) have focused on adult patients. Many of the previous recommendations have not been adapted to pediatric patients.
Agostoni, Agostoni, Agostoni, Altorjai, Andrew, Assadi, Aygoren-Pursun, Aygoren-Pursun, Bautista-Llacer, Bennett, Berkun, Betschel, Bork, Bork, Bork, Bork, Bork, Bouillet, Bouillet, Bouillet, Bowen, Bowen, Bowen, Bygum, Caballero, Caballero, Caballero, Caballero, Castelli, Chagas, Church, Cicardi, Cicardi, Cicardi, Cicardi, Cicardi, Craig, Craig, Craig, Craig, Craig, Csuka, Cugno, Czaller, Dinkel, Doherty, Ebo, El-Hachem, Fabiani, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Foix-L'Helias, Fouche, Gomez-Traseira, Gompels, Grumach, Grumach, Hogasen, Hubiche, Janardhanan, Kalmar, Kaplan, Kelemen, Kim, Kreuz, Kruger, Levy, Li, Lindecken, Longhurst, Lumry, MacGinnitie, Magerl, Martinez-Saguer, Martinez-Saguer, Martinez-Saguer, Martinez-Saguer, McCollough, Nanda, Nielsen, Nurnberger, O'Bier, Ohsawa, Pappalardo, Pappalardo, Pedrosa, Petraroli, Prior, Pritzker, Quintana, Rasmussen, Ren, Riedl, Riedl, Roach, Roche, Sanchez, Sanhueza, Shah, Speletas, Strawczynski, Tuong, Veszeli, Visy, Wahn, Wang, Wasserman, Wilson, Zanichelli, Zanichelli, Zilberberg, Zotter, Zotter, Zuraw, Zuraw, Zuraw   +122 more
core   +3 more sources

Characterization of carbohydrate chains of C1‐inhibitor and of desialylated C1‐inhibitor

FEBS Letters, 1992
Carbohydrate chains of C1‐inhibitor were identified with a binding assay using different lectins. Lectins from Sambucus nigra (SNA) and Maackia amurensis (MAA) that are specific for sialic acids bound to C1‐inhibitor. Lectin from Datura strantonium (DSA) reacted also with the inhibitor indicating complex and hybrid sugar structures.
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Possible role of extracellularly released phagocytic proteinases in the coagulation disorder during liver transplantation [PDF]

, 1991
Orthotopic liver transplantation is frequently associated with a complex coagulation disorder, influencing the outcome of the procedure. In this respect, disseminated intravascular coagulation (DIC) had been suggested to be of causative importance for ...
Blumhardt, G., Himmelreich, G., Jochum, Marianne, Machleidt, W., Neuhaus, P., Riess, H., Roissaint, R.   +6 more
core  

Fulminant systemic capillary leak syndrome due to C1 inhibitor deficiency complicating acute dermatomyositis: a case report [PDF]

, 2014
INTRODUCTION: Dermatomyositis is a chronic inflammatory disorder characterized by muscular and dermatologic symptoms with variable internal organ involvement.
Andreas Brunauer, Daniel Neureiter, Hermann Salmhofer, Ilse Gradwohl-Matis, Martin W Dünser, Romana Illig   +5 more
core   +1 more source