Results 41 to 50 of about 119,784 (210)
Modulation of C1-Inhibitor and Plasma Kallikrein Activities by Type IV Collagen
International Journal of Biomaterials, 2012 The contact system of coagulation can be activated when in contact with biomaterials. As collagen is being tested in novel biomaterials in this study, we have investigated how type IV collagen affects plasma kallikrein and C1-inhibitor.
Sriram Ravindran +2 more
doaj +1 more source
C1 inhibitor deficiency: consensus document [PDF]
Clinical and Experimental Immunology, 2005 SummaryWe present a consensus document on the diagnosis and management of C1 inhibitor deficiency, a syndrome characterized clinically by recurrent episodes of angio-oedema. In hereditary angio-oedema, a rare autosomal dominant condition, C1 inhibitor function is reduced due to impaired transcription or production of non-functional protein.
M M, Gompels +11 more
openaire +2 more sources
Possible role of extracellularly released phagocytic proteinases in the coagulation disorder during liver transplantation [PDF]
, 1991 Orthotopic liver transplantation is frequently associated with a complex coagulation disorder, influencing the outcome of the procedure. In this respect, disseminated intravascular coagulation (DIC) had been suggested to be of causative importance for ...
Blumhardt, G. +6 more
core
Delving into Vertebrate Serpins for Understanding their Evolution [PDF]
, 2009 The superfamily of serine proteinase inhibitors (serpins) is involved in an array of fundamental biological processes such as blood coagulation, cell differentiation, cell migration, complement activation, embryo implantation, fibrinolysis, angiogenesis,
Abhishek Kumar
core +2 more sources
Serial change of C1 inhibitor in patients with sepsis: a prospective observational study
Journal of Intensive Care, 2018 Background C1 inhibitor (C1-INH), which belongs to the superfamily of serine protease inhibitors, regulates the complement system and also the plasma kallikrein-kinin, fibrinolytic, and coagulation systems.
Tomoya Hirose +7 more
doaj +1 more source
Orphanet Journal of Rare Diseases, 2022 Hereditary angioedema (HAE) is a rare autosomal dominant genetic disease characterized by repetitive subcutaneous or submucosal angioedema, activation of the kinin system, and increased vascular permeability.
Yinshi Guo +6 more
doaj +1 more source
Oxidative stress markers in patients with hereditary angioedema
Archives of Medical Science, 2018 Introduction Hereditary angioedema due to C1-INH deficiency (C1-INH-HAE) or with normal C1-INH is characterized by recurrent swellings due to uncontrolled production of vasoactive mediators, among which bradykinin (BK) is crucial. Through the binding and
Stefano R. Del Giacco +8 more
doaj +1 more source
Polymorphisms in the bradykinin B2 receptor gene and childhood asthma [PDF]
, 2001 Bradykinin has been suggested as one of the key mediators of bronchial asthma. Polymorphisms with a potential functional relevance have been described in the B2 bradykinin receptor gene.
Braun, A. +5 more
core +1 more source
C1 Inhibitor Deficiency and Angioedema of the Small Intestine Masquerading as Crohn’s Disease
Canadian Journal of Gastroenterology, 2000 A case of C1 inhibitor deficiency presenting as localized edema of the small intestine is described. A 16-year-old, previously healthy woman presented with recurrent attacks of abdominal pain and vomiting following minor abdominal trauma.
Kelly W Burak, Gary R May
doaj +1 more source
Proteolytic Cleavage of Various Human Serum Proteinase Inhibitors by Candida albicans Aspartic Proteinase [PDF]
, 2008 The secreted Candida albicans aspartic proteinase (SAP) is presumed to be one of the putative Candida virulence factors, while serum proteinase inhibitors depend on host defense mechanisms.
Mine Hiroko, Tsushima Hirofumi
core +1 more source