Results 81 to 90 of about 721,729 (294)

Anti-C1-Inhibitor Autoantibody Detection by ELISA

, 2021
Enzyme-linked immunosorbent assay (ELISA) is a quantitative analytical method used to measure the concentration of molecules in biological fluids through antigen-antibody reactions.
Debora Parolin, Suffritti, Chiara, Cicardi, Marco, Berra, Silvia, Chiara Suffritti, Silvia Berra, Caccia, Sonia, Sonia Caccia, Parolin, Debora, Marco Cicardi   +9 more
core   +1 more source

Digitizing the Filtration Interface: A Smart, Modular Janus Wood Platform for Self‐Reporting Oil/Water Remediation

Advanced Functional Materials, EarlyView.
This work developed a smart Janus wood membrane integrating asymmetric wettability with built‐in electrical sensing for oil‐water separation. The membrane achieved > 99.5% separation efficiency and high flux by leveraging wood's natural anisotropic pore structure.
Kaiwen Chen, Cheng Hao, Wenjuan Zhao, Haonan Zhang, Yujing Tan, Fengze Sun, Xuewen Han, Hui Peng, Tianyi Zhan, Jianxiong Lyu, Ning Yan   +10 more
wiley   +1 more source

The effect of C1-esterase inhibitor on systemic inflammation in trauma patients with a femur fracture - The CAESAR study: study protocol for a randomized controlled trial

Trials, 2011
Background Systemic inflammation in response to a femur fracture and the additional fixation is associated with inflammatory complications, such as acute respiratory distress syndrome and multiple organ dysfunction syndrome.
Strengers Paul FW, Koenderman Anky HL, van Wessem Karlijn JP, Visser Tjaakje, Heeres Marjolein, Koenderman Leo, Leenen Luke PH   +6 more
doaj   +1 more source

WAO guideline for the management of hereditary angioedema

, 2012
Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers.
Ruby Pawankar, Richard Lockey, Magerl, Markus, Bowen, Tom, Lumry, William, Pawankar, Ruby, Craig, Timothy P., Craig, Timothy, Emel Aygören Pürsün, Anete Grumach, Bork, Konrad, Ritchie, Bruce, Katelaris, Constance H. (R12307), Bruce Zuraw, Alexander Nast, Farkas, Henrietta, Farkas, Henriette, Longhurst, Hilary, Martinez-Saguer, Immaculada, Nast, Alexander, Marcus Maurer, Henriette Farkas, Markus Magerl, Lockey, Richard, William Lumry, Tom Bowen, Zuraw, Bruce, Boysen, Henrik B., Martinez Saguer, Inmaculada, Konrad Bork, Grumach, Anete, Katelaris, Constance H., Hilary Longhurst, Aygören-Pürsün, Emel, Maurer, Marcus, Immaculada Martinez-Saguer, Bruce Ritchie, Henrik Boysen, Constance H. Katelaris, Timothy Craig   +39 more
core   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Structural and Functional Aspects of C1-Inhibitor

Immunobiology, 2002
C1-Inh is a serpin that inhibits serine proteases from the complement and the coagulation pathway. C1-Inh consists of a serpin domain and a unique N-terminal domain and is heavily glycosylated. Non-functional mutants of C1-Inh can give insight into the inhibitory mechanism of C1-Inh.
Bos, I.G.A., Hack, C.E., Abrahams, J.P.
openaire   +4 more sources

Inhibition of plasma kallikrein by C1-inhibitor: role of endothelial cells and the amino-terminal domain of C1-inhibitor.

, 2004
Activation of plasma prekallikein and generation of bradykinin are responsible for the angioedema attacks observed with C1-inhibitor deficiency. Heterozygous individuals with
Schapira, M., Ravindran, S., Welch, R.A., Grys, T.E., Patston, P.A.   +4 more
core   +1 more source

The hereditary angioedema burden of illness study in Europe (HAE-BOIS-Europe) : background and methodology [PDF]

, 2012
Background: Hereditary angioedema (HAE) is a rare but serious disease marked by swelling attacks in the extremities, face, trunk, airway, or abdominal areas that can be spontaneous or the result of trauma and other triggers.
Beusterien, Kathleen, Caballero, Teresa, Boysen, Henrik, Boysen, Henrik B., Musingarimi, Patience, Emel Aygören-Pürsün, Kathleen Beusterien, Gholizadeh, Shadi, Bygum, Anette, Wait, Suzanne, Patience Musingarimi, Aygören-Pürsün, Emel, Teresa Caballero, Suzanne Wait, Henrik Boysen, Anette Bygum, Shadi Gholizadeh, Bygum, Anette; id_orcid   +17 more
core   +1 more source

Functional Precision Oncology Approach Using Nanoliter Droplet Array for Drug Sensitivity Testing in Lung Cancer

Advanced Healthcare Materials, EarlyView.
A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian, Vicky L. Schiling, Thomas Muley, Michael Allgäuer, Florian Eichhorn, Michael Meister, Marc A. Schneider, Anna A. Popova   +7 more
wiley   +1 more source

Insights into the Purification of C1-esterase Inhibitor from Human Plasma

Plasmatology
Hereditary angioedema (HAE) is a rare but often life-threatening genetic disorder caused by either lack of or dysfunctional C1-esterase inhibitor (C1-I3NH). C1-INH is a high-cost therapy for HAE.
Sachin Verma, Sheetal Dolia, Savan Makadia, Narendra Kumar   +3 more
doaj   +1 more source