Results 81 to 90 of about 119,784 (210)

Nine year follow-up of a rare case of angioedema due to acquired C1-inhibitor deficiency with late onset and good response to attenuated androgen

Allergy, Asthma & Clinical Immunology, 2018
Background Angioedema due to acquired deficiency of C1-inhibitor (C1-INH-AAE) is a rare disease sharing some clinical and laboratory similarities with hereditary angioedema, but with late onset and no positive family history. The underlining cause may be
Polliana Mihaela Leru, Vlad Florin Anton, Horia Bumbea   +2 more
doaj   +1 more source

Vasculopathy: a possible factor affecting hereditary angioedema

Bleeding, Thrombosis and Vascular Biology
Hereditary angioedema (HAE) is a rare genetic disorder that causes swelling of tissues in the hands, feet, limbs, face, intestinal tract, or airway. The SERPING1 gene, encoding the C1-INH, determines the wide range of clinical symptoms associated with ...
Anna Laura Colia, Alessandra Ranaldi, Rosa Santacroce, Giovanna D'Andrea, Angela Bruna Maffione, Maurizio Margaglione, Maria D'Apolito   +6 more
doaj   +1 more source

The differential ability of human IgG1 and IgG4 to activate complement is determined by the COOH-terminal sequence of the CH2 domain. [PDF]

, 1991
Using domain switch chimeric antibodies, we confirm the important role of CH2 in complement activation. In addition, we demonstrate that the structures responsible for the differential ability of human IgG1 and IgG4 to activate complement are located at ...
Canfield, SM, Morrison, SL, Tao, MH
core  

International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1-Inhibitor deficiency [PDF]

, 2016
BACKGROUND: The consensus documents published to date on hereditary angioedema with C1-inhibitor deficiency (C1-INH-HAE) have focused on adult patients. Many of the previous recommendations have not been adapted to pediatric patients.
Agostoni, Agostoni, Agostoni, Altorjai, Andrew, Assadi, Aygoren-Pursun, Aygoren-Pursun, Bautista-Llacer, Bennett, Berkun, Betschel, Bork, Bork, Bork, Bork, Bork, Bouillet, Bouillet, Bouillet, Bowen, Bowen, Bowen, Bygum, Caballero, Caballero, Caballero, Caballero, Castelli, Chagas, Church, Cicardi, Cicardi, Cicardi, Cicardi, Cicardi, Craig, Craig, Craig, Craig, Craig, Csuka, Cugno, Czaller, Dinkel, Doherty, Ebo, El-Hachem, Fabiani, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Farkas, Foix-L'Helias, Fouche, Gomez-Traseira, Gompels, Grumach, Grumach, Hogasen, Hubiche, Janardhanan, Kalmar, Kaplan, Kelemen, Kim, Kreuz, Kruger, Levy, Li, Lindecken, Longhurst, Lumry, MacGinnitie, Magerl, Martinez-Saguer, Martinez-Saguer, Martinez-Saguer, Martinez-Saguer, McCollough, Nanda, Nielsen, Nurnberger, O'Bier, Ohsawa, Pappalardo, Pappalardo, Pedrosa, Petraroli, Prior, Pritzker, Quintana, Rasmussen, Ren, Riedl, Riedl, Roach, Roche, Sanchez, Sanhueza, Shah, Speletas, Strawczynski, Tuong, Veszeli, Visy, Wahn, Wang, Wasserman, Wilson, Zanichelli, Zanichelli, Zilberberg, Zotter, Zotter, Zuraw, Zuraw, Zuraw   +122 more
core   +3 more sources

Mechanism and therapy of hereditary angioedema typ III and role of the contact system in inflammatory diseases [PDF]

, 2014
Combinations of proinflammatory and procoagulant reactions are associated with a variety of disorders affecting the cardiovascular system. Vascular leakage contributes to the pathology of conditions such as, sepsis, allergy and anaphylactic reactions ...
Björkqvist, Jenny
core   +1 more source

Personalized biological treatment with lanadelumab in a patient with recurrent attacks of hereditary angioedema

Alergologia Polska
Hereditary angioedema (HAE) is an autosomal dominantly inherited disease caused by deficiency of C1 esterase inhibitor protein type 1 (about 85% of patients with HAE-C1-INH) or type 2 oedema (about 15% of patients with HAE-C1-INH) by C1 inhibitor ...
Artur Gęsicki, Maciej F. Kozlowski, Karolina Żurawska, Weronika Ossowska, Jakub Sikora, Szymon Dyguś, Iwona Poziomkowska-Gęsicka   +6 more
doaj   +1 more source

The physician and hereditary angioedema friend or foe: 62-year diagnostic delay and iatrogenic procedures

Allergy, Asthma & Clinical Immunology, 2018
Background Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is a rare autosomal dominant disease characterized by episodes of acute subcutaneous swelling, and/or recurrent severe abdominal pain.
Anna Valerieva, Marco Cicardi, James Baraniuk, Maria Staevska   +3 more
doaj   +1 more source

Molecular Genetics of C1 Inhibitor

Immunobiology, 1998
More than 100 different C1 inhibitor gene mutations have been described in hereditary angioedema (HAE) patients. Sixty-nine mutations have been reported in patients with the quantitative C1 inhibitor defect (type 1 HAE) in two recent large-scale studies. These changes were found distributed over all exons and exon/intron boundaries.
openaire   +2 more sources

Herediter anjioödemde kısa dönem danazol profilaksisi ile implant tedavisi: Vaka raporu

Selcuk Dental Journal, 2019
Herediter anjio ödem (HAÖ), C1 esteraz inhibitör proteininin konjenital eksikliğine bağlı olarak meydana gelen, nadir gözlenen, otozomal dominant bir hastalıktır. HAÖ atakları, spontan veya bir travmaya bağlı olarak, ekstremitelerde, yüzde, göğüste, hava
Zeynep Burçin Gönen, Fatma Doğruel, Canay Yılmaz Asan, Leylagül Kaynar, Mustafa Çetin   +4 more
doaj   +1 more source

Consensus statement on the diagnosis, management, and treatment of angioedema mediated by Bradykinin. Part. II: treatment, follow-up, and special situations [PDF]

, 2011
Background: There are no previous Spanish guidelines or consensus statements on bradykinin-induced angioedema. Aim: To draft a consensus statement on the management and treatment of angioedema mediated by bradykinin in light of currently available ...
Baeza, M. L., Caballero, T., Cabañas, R., Campos, A., Cimbollek, S., González-Quevedo, T., Guilarte, M., Gómez-Traseira, C., Jurado-Palomo, J., Larco, J. I., López-Serrano, M. C., López-Trascasa, Margarita, Marcos, C., Muñoz- Caro, J. M., Pedrosa, M., Prior, N., Rubio, M., Sala-Cunill, A.   +17 more
core   +1 more source