Results 151 to 160 of about 98,834 (305)

C1 inhibitor deficiency: consensus document

We present a consensus document on the diagnosis and management of C1 inhibitor deficiency, a syndrome characterized clinically by recurrent episodes of angio-oedema.
Morrison L, Fay AC, Price M, Grattan C, Lock RJ, Davies G, Gompels MM, Bethune CA, Longhurst HJ, Price A, Abinun M, Watters D   +11 more
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Hereditary angioedema caused by C1-esterase inhibitor deficiency: a case report with literature-based analysis

, 2019
Hereditary angioedema (HAE) caused by C1-esterase inhibitor deficiency is an autosomal-dominant disease caused by a mutation in the C1-inhibitor gene. It is a rare disease that is often worsened during pregnancy and childbirth.
Athar, Sufia, Korichi, Noureddine, Siam, Yousra Shehada   +2 more
core   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Case Report: Early presentation of hereditary angioedema symptoms in a 2-year-old boy

Frontiers in Pediatrics
Hereditary angioedema (HAE) is a rare autosomal-dominant disease that is caused by a deficiency (type I) or dysfunction (type II) of the C1 inhibitor (C1-INH) due to a mutation in the SERPING1 gene, which codes for C1-INH.
Jurate Staikuniene-Kozonis, Jurate Staikuniene-Kozonis, Juste Staikunaite, Juste Staikunaite, Edita Gasiuniene, Justina Sematonyte   +5 more
doaj   +1 more source

Current treatment options for hereditary angioedema due to C1 inhibitor deficiency

, 2016
Introduction: Hereditary angioedema (HAE) usually results from C1 inhibitor (C1-INH) deficiency or dysfunction. It is a rare autosomal dominant disorder characterized by localized, non-pitting edema of the skin and submucosal tissues of the upper ...
A. Zanichelli, Maddalena Alessandra Wu, M. Cicardi, Andrea Zanichelli, Marta Mansi, Marco Cicardi, M. Mansi, M. A. Wu   +7 more
core   +1 more source

Hierarchical Ordering Induced Ultrahigh Cryogenic Strength and Strain Hardening in a Ni2CoFeV Medium‐Entropy Alloy

Advanced Science, EarlyView.
A tri‐phase Ni2CoFeV medium‐entropy alloy with fcc, κ, and L12 phases achieves exceptional cryogenic strength‐ductility synergy at 77 K. It delivers a yield strength of 1.4 GPa, an ultimate tensile strength of 2.07 GPa and a tensile ductility of 28%.
Lei Gu, Wei Jiang, Qingzhong Mao, Xiang Chen, Yonghao Zhao   +4 more
wiley   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

A Case of C1-İnhibitor Deficiency With Familial Mediterranean Fever

, 2009
C1 inhibitor (C1-INH) eksikliği ilk kez 1881 yılında tanımlanmıstır. Hastalığın pre- valansının 1/50000 olduğu tahmin edilmektedir. CI-INH eksikliği nadir görülmesine rağmen, birçok hastalığın seyri sırasında da gelisebilmektedir.
Peru, Harun, Elmacı, Ahmet Midhat, Akın, Fatih   +2 more
core   +1 more source

Acquired C1 inbibitor deficiency associated with SLE

, 2001
Acquired C1 inhibitor deficiency is a rare syndrome which usually presents with episodes of angioedema. The association of lupus erythematosus and angioneurotic edema has been previously reported but is usually related to hereditary C1 inhibitor ...
이원기, 이수곤, 송정식, 박용범, 강이화   +4 more
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